Search Results - "Rubinstein, Paul G."
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KSHV/HHV8-mediated hematologic diseases
Published in Blood (17-02-2022)“…Kaposi sarcoma (KS) herpesvirus (KSHV), also known as human herpesvirus 8, is the causal agent of KS but is also pathogenetically related to several…”
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Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells
Published in Blood (12-02-2015)“…Classical Hodgkin lymphoma (cHL) is characterized by sparsely distributed Hodgkin and Reed-Sternberg (HRS) cells amid reactive host background, complicating…”
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Long-term survival in AIDS-related primary central nervous system lymphoma
Published in Neuro-oncology (Charlottesville, Va.) (01-01-2017)“…The optimal therapeutic approach for patients with AIDS-related primary central nervous system lymphoma (AR-PCNSL) remains undefined. While its incidence…”
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Metagenomic analysis to identify novel infectious agents in systemic anaplastic large cell lymphoma
Published in Infectious agents and cancer (14-11-2021)“…Abstract Systemic anaplastic large cell lymphoma (ALCL) is a rare CD30-expressing T-cell non-Hodgkin lymphoma. Risk of systemic ALCL is highly increased among…”
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Malignancies in HIV/AIDS: from epidemiology to therapeutic challenges
Published in AIDS (London) (20-02-2014)“…The incidence of AIDS-defining cancers (ADCs) – Kaposi sarcoma, primary central nervous system lymphoma, non-Hodgkin lymphoma, and cervical cancer – although…”
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Hematopoietic stem cell transplantation and cellular therapy in persons living with HIV
Published in Current opinion in infectious diseases (01-08-2024)“…Summarize the latest research of both stem cell transplantation and cellular therapy and present the implications with respect to persons with HIV (PWH),…”
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Impact of Myc in HIV-associated non-Hodgkin lymphomas treated with EPOCH and outcomes with vorinostat (AMC-075 trial)
Published in Blood (10-09-2020)“…EPOCH (etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin) is a preferred regimen for HIV-non-Hodgkin lymphomas (HIV-NHLs), which are…”
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Assessment of the safety of nivolumab in people living with HIV with advanced cancer on antiretroviral therapy: the AIDS Malignancy Consortium 095 Study
Published in Cancer (15-03-2024)“…Background Although immunotherapy has emerged as a therapeutic strategy for many cancers, there are limited studies establishing the safety and efficacy in…”
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Brentuximab vedotin with AVD shows safety, in the absence of strong CYP3A4 inhibitors, in newly diagnosed HIV-associated Hodgkin lymphoma
Published in AIDS (London) (13-03-2018)“…OBJECTIVE:Brentuximab vedotin is a Food and Drug Administration approved anti-CD30 antibody drug conjugate potently active in Hodgkin lymphoma. Trials of…”
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Wilms' tumor 1 (WT1) antigen is overexpressed in Kaposi Sarcoma and is regulated by KSHV vFLIP
Published in PLoS pathogens (01-01-2024)“…In people living with HIV, Kaposi Sarcoma (KS), a vascular neoplasm caused by KS herpesvirus (KSHV/HHV-8), remains one of the most common malignancies…”
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Real-World Multicenter Study of PD-1 Blockade in HIV-Associated Classical Hodgkin Lymphoma Across the United States
Published in Clinical lymphoma, myeloma and leukemia (01-08-2024)“…Despite a higher risk of classical Hodgkin lymphoma (cHL) in people with HIV and the demonstrated safety and efficacy of PD-1 blockade in cHL, there are…”
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Brentuximab vedotin with AVD for stage II–IV HIV-related Hodgkin lymphoma (AMC 085): phase 2 results from an open-label, single arm, multicentre phase 1/2 trial
Published in The Lancet. Haematology (01-08-2023)“…Brentuximab vedotin in combination with doxorubicin, vinblastine, and dacarbazine (AVD) is approved in the upfront setting for advanced stage classical Hodgkin…”
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High-grade B-cell lymphoma, not otherwise specified: a multi-institutional retrospective study
Published in Blood advances (14-11-2023)“…•HGBL-NOS is a highly heterogeneous category; PFS (55% at 2 years) did not significantly differ between R-CHOP and intensified regimens.•A dual-expressor (MYC…”
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Initial Experience with the Use of Thrombopoetin Receptor Agonists in Patients with Refractory HIV-Associated Immune Thrombocytopenic Purpura: A Case Series
Published in Journal of the International Association of Providers of AIDS Care (01-05-2015)“…HIV-associated immune thrombocytopenic purpura (ITP) has decreased in incidence 10-fold since the advent of highly active antiretroviral therapy (HAART). For…”
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Initial Experience with the Use of Thrombopoetin Receptor Agonists in Patients with Refractory HIV-Associated Immune Thrombocytopenic Purpura
Published in Journal of the International Association of Providers of AIDS Care (01-05-2015)“…HIV-associated immune thrombocytopenic purpura (ITP) has decreased in incidence 10-fold since the advent of highly active antiretroviral therapy (HAART). For…”
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Delayed hemolysis after intravenous anti‐D immune globulin infusion in a patient with idiopathic thrombocytopenic purpura
Published in American journal of hematology (01-08-2008)Get full text
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Prevalence and outcomes of sepsis in HIV versus non-HIV patients with diffuse large B-cell lymphoma: A nationwide analysis
Published in Journal of clinical oncology (20-05-2021)“…Abstract only e19567 Background: With the advent combined anti-retroviral therapy (ART), the survival of people living with HIV has improved, thereby…”
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