Search Results - "Rubinstein, German"
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Time to Diagnosis in Cushing’s Syndrome: A Meta-Analysis Based on 5367 Patients
Published in The journal of clinical endocrinology and metabolism (01-03-2020)“…Abstract Context Signs and symptoms of Cushing’s syndrome (CS) overlap with common diseases, such as the metabolic syndrome, obesity, osteoporosis, and…”
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Long-Term Outcome of Primary Bilateral Macronodular Adrenocortical Hyperplasia After Unilateral Adrenalectomy
Published in The journal of clinical endocrinology and metabolism (01-07-2019)“…Abstract Context Unilateral adrenalectomy has been proposed in selected patients with primary bilateral macronodular adrenocortical hyperplasia (PBMAH), but…”
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The Effect of Biochemical Remission on Bone Metabolism in Cushing's Syndrome: A 2‐Year Follow‐Up Study
Published in Journal of bone and mineral research (01-09-2020)“…ABSTRACT Endogenous Cushing's syndrome (CS) is a rare cause of secondary osteoporosis. The long‐term consequences for bone metabolism after successful surgical…”
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Corticotroph tumor progression after bilateral adrenalectomy (Nelson’s syndrome): systematic review and expert consensus recommendations
Published in European journal of endocrinology (01-03-2021)“…Background Corticotroph tumor progression (CTP) leading to Nelson’s syndrome (NS) is a severe and difficult-to-treat complication subsequent to bilateral…”
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Toward a Diagnostic Score in Cushing's Syndrome
Published in Frontiers in endocrinology (Lausanne) (08-11-2019)“…Cushing's syndrome (CS) is a classical rare disease: it is often suspected in patients who do not have the disease; at the same time, it takes a mean of 3…”
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Metformin and Bone Metabolism in Endogenous Glucocorticoid Excess: An Exploratory Study
Published in Frontiers in endocrinology (Lausanne) (27-10-2021)“…Glucocorticoid excess exhibits multiple detrimental effects by its catabolic properties. Metformin was recently suggested to protect from adverse metabolic…”
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Steroid profiling using liquid chromatography mass spectrometry during adrenal vein sampling in patients with primary bilateral macronodular adrenocortical hyperplasia
Published in Frontiers in endocrinology (Lausanne) (06-12-2022)“…Adrenal vein sampling (AVS) is not a routine procedure in patients with primary bilateral macronodular adrenocortical hyperplasia (PBMAH), but has been used to…”
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Frequency of clinical signs in patients with Cushing's syndrome and mild autonomous cortisol secretion (MACS): Overlap is common
Published in European journal of endocrinology (30-09-2024)“…Cushing's syndrome (CS) can be difficult to diagnose. A timely diagnosis, however, is the cornerstone for targeted treatment, to reduce morbidity and…”
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Therapeutic options after surgical failure in Cushing's disease: A critical review
Published in Baillière's best practice & research. Clinical endocrinology & metabolism (01-04-2019)“…Cushing's disease (CD) is the most common etiology of Cushing's syndrome (CD) due to corticotroph pituitary adenoma, which are in most cases small (80–90%…”
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Whom Should We Screen for Cushing Syndrome? The Endocrine Society Practice Guideline Recommendations 2008 Revisited
Published in The journal of clinical endocrinology and metabolism (01-09-2022)“…Abstract Context Cushing syndrome (CS) is a rare and serious disease with high mortality. Patients are often diagnosed late in the course of the disease…”
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Diagnostic challenges in cyclic Cushing's syndrome: a systematic review
Published in The lancet. Diabetes & endocrinology (01-08-2023)“…Cyclic Cushing's syndrome is a subentity of Cushing's syndrome in which phases of biochemical hypercortisolism (peaks) are followed by spontaneous periods of…”
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Patients with low IGF-I after curative surgery for Cushing’s syndrome have an adverse long-term outcome of hypercortisolism-induced myopathy
Published in European journal of endocrinology (01-06-2021)“…Background Glucocorticoid excess leads to muscle atrophy and weakness in patients with endogenous Cushing’s syndrome. Insulin-like growth factor I (IGF-I) is…”
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Recurrence after pituitary surgery in adult Cushing’s disease: a systematic review on diagnosis and treatment
Published in Endocrine (01-11-2020)“…Purpose Recurrence after pituitary surgery in Cushing’s disease (CD) is a common problem ranging from 5% (minimum) to 50% (maximum) after initially successful…”
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Persisting Muscle Dysfunction in Cushing’s Syndrome Despite Biochemical Remission
Published in The journal of clinical endocrinology and metabolism (01-12-2020)“…Abstract Context Glucocorticoid-induced myopathy is a characteristic symptom of endogenous Cushing’s syndrome (CS). Its long-term outcome is largely unknown…”
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Biochemical Control in Cushing's syndrome: Outcomes of the treatment in a large single center cohort
Published in The journal of clinical endocrinology and metabolism (20-05-2024)“…Normalization of hypercortisolism is essential to reduce morbidity and mortality in patients with Cushing's syndrome (CS). The aim of this analysis was to…”
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Low-grade inflammation during the glucocorticoid withdrawal phase in patients with Cushing's syndrome
Published in European journal of endocrinology (05-04-2023)“…Endogenous Cushing's syndrome (CS) leads to profound immunosuppression. Successful surgery induces biochemical remission and reversal of immunosuppression,…”
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Glucocorticoid receptor polymorphism Bcl I with increased glucocorticoid sensitivity has a positive influence on quality of life in endogenous Cushing's syndrome in remission
Published in European journal of endocrinology (05-04-2023)“…Abstract Context Patients with endogenous Cushing's syndrome (CS) may suffer from a wide range of neuropsychiatric symptoms leading to impaired quality of life…”
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Prevalence and Outcome of Secondary Hypogonadism in Male Patients with Cushing's Syndrome and Mild Autonomous Cortisol Secretion
Published in European journal of endocrinology (05-08-2024)“…Secondary hypogonadism (SH) is common in men with Cushing's syndrome (CS), but its impact on comorbidities is largely unknown and longitudinal data are scarce…”
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Lack of sensitivity of diagnostic Cushing-scores in Germany: a multicenter validation
Published in European journal of endocrinology (10-01-2023)“…Endogenous Cushing's syndrome (CS) is a severe condition, often diagnosed at a late stage. To reduce mortality, early diagnosis plays an important role. Two…”
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Glucocorticoid receptor polymorphism BclI with increased glucocorticoid sensitivity has a positive influence on quality of life in endogenous Cushing's syndrome in remission
Published in European journal of endocrinology (05-04-2023)“…Patients with endogenous Cushing's syndrome (CS) may suffer from a wide range of neuropsychiatric symptoms leading to impaired quality of life (QoL)…”
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