Search Results - "Rubin, T"

Extraintestinal Manifestations of Inflammatory Bowel Disease: Current Concepts, Treatment, and Implications for Disease Management by Rogler, Gerhard, Singh, Abha, Kavanaugh, Arthur, Rubin, David T.

“…Inflammatory bowel diseases (IBDs) are systemic diseases that manifest not only in the gut and gastrointestinal tract, but also in the extraintestinal organs…”
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ACG Clinical Guideline: Ulcerative Colitis in Adults by Rubin, David T, Ananthakrishnan, Ashwin N, Siegel, Corey A, Sauer, Bryan G, Long, Millie D

“…Ulcerative colitis (UC) is an idiopathic inflammatory disorder. These guidelines indicate the preferred approach to the management of adults with UC and…”
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AGA Clinical Practice Update on Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: Expert Commentary by Rubin, David T., Feuerstein, Joseph D., Wang, Andrew Y., Cohen, Russell D.

“…The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update was to rapidly review the emerging evidence and provide…”
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Fecal microbiota transplantation as therapy for inflammatory bowel disease: A systematic review and meta-analysis by Colman, Ruben J., Rubin, David T.

“…A correction notice has been published, see: https://doi.org/10.1093/ecco-jcc/jjac104 Fecal microbiota transplantation (FMT) has gained interest as a novel…”
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Mechanical regulation of signaling pathways in bone by Thompson, William R., Rubin, Clinton T., Rubin, Janet

“…A wide range of cell types depend on mechanically induced signals to enable appropriate physiological responses. The skeleton is particularly dependent on…”
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The Cost of Inflammatory Bowel Disease: An Initiative From the Crohn’s & Colitis Foundation by Park, K T, Ehrlich, Orna G, Allen, John I, Meadows, Perry, Szigethy, Eva M, Henrichsen, Kim, Kim, Sandra C, Lawton, Rachel C, Murphy, Sean M, Regueiro, Miguel, Rubin, David T, Engel-Nitz, Nicole M, Heller, Caren A

“…This study quantifies the wide-ranging health care costs affecting patients living with IBD, including the annualized direct and indirect costs of care for…”
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Consequences of irradiation on bone and marrow phenotypes, and its relation to disruption of hematopoietic precursors by Green, Danielle E, Rubin, Clinton T

“…Abstract The rising levels of radiation exposure, specifically for medical treatments and accidental exposures, have added great concern for the long term…”
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Inclusion of Under-represented Racial and Ethnic Minorities in Randomized Clinical Trials for Inflammatory Bowel Disease by Cohen, Nathaniel A., Silfen, Alexa, Rubin, David T.

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Indicators of suboptimal biologic therapy over time in patients with ulcerative colitis and Crohn's disease in the United States by Patel, Haridarshan, Lissoos, Trevor, Rubin, David T

“…This study assessed the occurrence of indicators for suboptimal biologic therapy among ulcerative colitis (UC) and Crohn's disease (CD) patients over time in…”
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Mechanical signals as anabolic agents in bone by Rubin, Clinton T, Ozcivici, Engin, Luu, Yen Kim, Adler, Ben, Qin, Yi-Xian, Rubin, Janet, Judex, Stefan

“…A reduction in mechanical loading of the skeleton resulting from aging or a sedentary lifestyle can confer an increased risk of fracture through reductions in…”
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Exercise Decreases Marrow Adipose Tissue Through ß‐Oxidation in Obese Running Mice by Styner, Maya, Pagnotti, Gabriel M, McGrath, Cody, Wu, Xin, Sen, Buer, Uzer, Gunes, Xie, Zhihui, Zong, Xiaopeng, Styner, Martin A, Rubin, Clinton T, Rubin, Janet

“…ABSTRACT The relationship between marrow adipose tissue (MAT) and bone health is poorly understood. We used running exercise to ask whether obesity‐associated…”
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Hippocampal gene expression changes underlying stress sensitization and recovery by Gray, J D, Rubin, T G, Hunter, R G, McEwen, B S

“…Chronic and acute stressors have been linked to changes in hippocampal function and anxiety-like behaviors. Both produce changes in gene expression, but the…”
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Mechanical Stimulation of Mesenchymal Stem Cell Proliferation and Differentiation Promotes Osteogenesis While Preventing Dietary‐Induced Obesity by Luu, Yen Kim, Capilla, Encarnacion, Rosen, Clifford J, Gilsanz, Vicente, Pessin, Jeffrey E, Judex, Stefan, Rubin, Clinton T

“…Mesenchymal stem cells (MSCs) are defined by their ability to self‐renew and differentiate into the cells that form mesodermal tissues such as bone and fat…”
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Low-level vibrations retain bone marrow's osteogenic potential and augment recovery of trabecular bone during reambulation by Ozcivici, Engin, Luu, Yen K, Rubin, Clinton T, Judex, Stefan

“…Mechanical disuse will bias bone marrow stromal cells towards adipogenesis, ultimately compromising the regenerative capacity of the stem cell pool and…”
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Cell Mechanosensitivity to Extremely Low‐Magnitude Signals Is Enabled by a LINCed Nucleus by Uzer, Gunes, Thompson, William R., Sen, Buer, Xie, Zhihui, Yen, Sherwin S., Miller, Sean, Bas, Guniz, Styner, Maya, Rubin, Clinton T., Judex, Stefan, Burridge, Keith, Rubin, Janet

“…A cell's ability to recognize and adapt to the physical environment is central to its survival and function, but how mechanical cues are perceived and…”
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miR-193a-3p is a Key Tumor Suppressor in Ulcerative Colitis-Associated Colon Cancer and Promotes Carcinogenesis through Upregulation of IL17RD by Pekow, Joel, Meckel, Katherine, Dougherty, Urszula, Huang, Yong, Chen, Xindi, Almoghrabi, Anas, Mustafi, Reba, Ayaloglu-Butun, Fatma, Deng, Zifeng, Haider, Haider I, Hart, John, Rubin, David T, Kwon, John H, Bissonnette, Marc

“…Patients with ulcerative colitis are at increased risk for colorectal cancer, although mechanisms underlying neoplastic transformation are poorly understood…”
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Long-term Efficacy of Vedolizumab for Ulcerative Colitis by Loftus, Jr, Edward V, Colombel, Jean-Frédéric, Feagan, Brian G, Vermeire, Severine, Sandborn, William J, Sands, Bruce E, Danese, Silvio, D'Haens, Geert R, Kaser, Arthur, Panaccione, Remo, Rubin, David T, Shafran, Ira, McAuliffe, Megan, Kaviya, Arpeat, Sankoh, Serap, Mody, Reema, Abhyankar, Brihad, Smyth, Michael

“…The GEMINI long-term safety [LTS] study is a continuing phase 3 trial investigating the safety and efficacy of vedolizumab, an α4β7 integrin antagonist for…”
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Long-term Efficacy of Vedolizumab for Crohn's Disease by Vermeire, Severine, Loftus, Jr, Edward V, Colombel, Jean-Frédéric, Feagan, Brian G, Sandborn, William J, Sands, Bruce E, Danese, Silvio, D'Haens, Geert R, Kaser, Arthur, Panaccione, Remo, Rubin, David T, Shafran, Ira, McAuliffe, Megan, Kaviya, Arpeat, Sankoh, Serap, Mody, Reema, Abhyankar, Brihad, Smyth, Michael

“…Vedolizumab is a gut-selective α4β7 integrin antagonist therapy for ulcerative colitis and Crohn's disease. The GEMINI long-term safety [LTS] trial is an…”
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Barbiturates and pyrazolopyridines for the treatment of postpartum depression-repurposing of two drug classes by Horwitz, Alexander B, Rubin, Robert T

“…Zulresso (brexanolone) is an aqueous formulation of the neurosteroid, allopregnanolone, and the only FDA-approved medication for the treatment of postpartum…”
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Assessment of the relationship between quality of sleep and disease activity in inflammatory bowel disease patients by Ali, Tauseef, Madhoun, Mohammad F, Orr, William C, Rubin, David T

“…Poor sleep quality is associated with adverse health consequences. Sleep disturbances can impact the immune function and process of inflammation. The…”
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