Search Results - "Rubin, J. S."

Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility by Aprelikova, O, Palla, J, Hibler, B, Yu, X, Greer, Y E, Yi, M, Stephens, R, Maxwell, G L, Jazaeri, A, Risinger, J I, Rubin, J S, Niederhuber, J

“…The tumor microenvironment has an important role in cancer progression. Here we show that miR-148a is downregulated in 15 out of 16 samples (94%) of…”
Get full text

Automated spatial omics landscape analysis approach reveals novel tissue architectures in ulcerative colitis by Holman, Derek R., Rubin, Samuel J. S., Ferenc, Mariusz, Holman, Elizabeth A., Koron, Alexander N., Daniel, Robel, Boland, Brigid S., Nolan, Garry P., Chang, John T., Rogalla, Stephan

“…The utility of spatial omics in leveraging cellular interactions in normal and diseased states for precision medicine is hampered by a lack of strategies for…”
Get full text

Mass cytometry reveals systemic and local immune signatures that distinguish inflammatory bowel diseases by Rubin, Samuel J. S., Bai, Lawrence, Haileselassie, Yeneneh, Garay, Gotzone, Yun, Chohee, Becker, Laren, Streett, Sarah E., Sinha, Sidhartha R., Habtezion, Aida

“…Inflammatory bowel disease (IBD) includes Crohn’s disease and ulcerative colitis. Each disease is characterized by a diverse set of potential manifestations,…”
Get full text

An Update on Protein Kinases as Therapeutic Targets-Part I: Protein Kinase C Activation and Its Role in Cancer and Cardiovascular Diseases by Silnitsky, Shmuel, Rubin, Samuel J S, Zerihun, Mulate, Qvit, Nir

“…Protein kinases are one of the most significant drug targets in the human proteome, historically harnessed for the treatment of cancer, cardiovascular disease,…”
Get full text

An Update on Protein Kinases as Therapeutic Targets-Part II: Peptides as Allosteric Protein Kinase C Modulators Targeting Protein-Protein Interactions by Zerihun, Mulate, Rubin, Samuel J S, Silnitsky, Shmuel, Qvit, Nir

“…Human protein kinases are highly-sought-after drug targets, historically harnessed for treating cancer, cardiovascular disease, and an increasing number of…”
Get full text

B cell checkpoints in autoimmune rheumatic diseases by Rubin, Samuel J. S., Bloom, Michelle S., Robinson, William H.

“…B cells have important functions in the pathogenesis of autoimmune diseases, including autoimmune rheumatic diseases. In addition to producing autoantibodies,…”
Get full text

Reliability of OperaVOX against Multidimensional Voice Program (MDVP) by Mat Baki, M., Wood, G., Alston, M., Ratcliffe, P., Sandhu, G., Rubin, J.S., Birchall, M.A.

“…Objective To evaluate the agreement between OperaVOX and MDVP. Design Cross sectional reliability study. Setting University teaching hospital. Methods Fifty…”
Get full text

Looking to Future Applications of Large Language Models by Liu, Xichong, Rubin, Samuel J S, Rogalla, Stephan

Get full text

Metalloendopeptidase ADAM-like Decysin 1 (ADAMDEC1) in Colonic Subepithelial PDGFRα + Cells Is a New Marker for Inflammatory Bowel Disease by Ha, Se Eun, Jorgensen, Brian G, Wei, Lai, Jin, Byungchang, Kim, Min-Seob, Poudrier, Sandra M, Singh, Rajan, Bartlett, Allison, Zogg, Hannah, Kim, Sei, Baek, Gain, Kurahashi, Masaaki, Lee, Moon-Young, Kim, Yong-Sung, Choi, Suck-Chei, Sasse, Kent C, Rubin, Samuel J S, Gottfried-Blackmore, Andres, Becker, Laren, Habtezion, Aida, Sanders, Kenton M, Ro, Seungil

“…Metalloendopeptidase ADAM-Like Decysin 1 (ADAMDEC1) is an anti-inflammatory peptidase that is almost exclusively expressed in the gastrointestinal (GI) tract…”
Get full text

Clinical characteristics associated with COVID-19 severity in California by Rubin, Samuel J. S., Falkson, Samuel R., Degner, Nicholas R., Blish, Catherine

“…Given the rapidly progressing coronavirus disease 2019 (COVID-19) pandemic, this report on a US cohort of 54 COVID-19 patients from Stanford Hospital and data…”
Get full text

Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity by Fenton, Thomas M., Jørgensen, Peter B., Niss, Kristoffer, Rubin, Samuel J.S., Mörbe, Urs M., Riis, Lene B., Da Silva, Clément, Plumb, Adam, Vandamme, Julien, Jakobsen, Henrik L., Brunak, Søren, Habtezion, Aida, Nielsen, Ole H., Johansson-Lindbom, Bengt, Agace, William W.

“…The intestine contains some of the most diverse and complex immune compartments in the body. Here we describe a method for isolating human gut-associated…”
Get full text

The Tumor Immune Microenvironment in Pancreatic Ductal Adenocarcinoma: Neither Hot nor Cold by Rubin, Samuel J. S, Sojwal, Raoul S, Gubatan, John, Rogalla, Stephan

“…Pancreatic ductal adenocarcinoma (PDAC) is the most common pancreatic tumor and is associated with poor prognosis and treatment response. The tumor…”
Get full text

Comparing the diagnosis of laryngopharyngeal reflux between the reflux symptom index, clinical consultation and reflux finding score in a group of patients presenting to an ENT clinic with an interest in voice disorders: a pilot study in thirty-five patients by Watson, N.A., Kwame, I., Oakeshott, P., Reid, F., Rubin, J.S.

Get full text

Anti-Integrins for the Treatment of Inflammatory Bowel Disease: Current Evidence and Perspectives by Gubatan, John, Keyashian, Kian, Rubin, Samuel J S, Wang, Jenny, Buckman, Cyrus A, Sinha, Sidhartha

“…Leukocyte trafficking to the gastrointestinal tract is recognized to play a role in the pathogenesis of inflammatory bowel disease (IBD). Integrins are…”
Get full text

Safety of ACE-I and ARB medications in COVID-19: A retrospective cohort study of inpatients and outpatients in California by Rubin, Samuel J S, Falkson, Samuel R, Degner, Nicholas R, Blish, Catherine A

“…There is significant interest in the use of angiotensin converting enzyme inhibitors (ACE-I) and angiotensin II receptor blockers (ARB) in coronavirus disease…”
Get full text

Conversion of Protein Active Regions into Peptidomimetic Therapeutic Leads Using Backbone Cyclization and Cycloscan - How to Do it Yourself by Rubin, Samuel J S, Tal-Gan, Yftah, Gilon, Chaim, Qvit, Nir

“…Protein-protein Interactions (PPIs) are particularly important for controlling both physiologic and pathologic biological processes but are difficult to target…”
Get more information

Keratinocyte growth factor and hepatocyte growth factor/scatter factor are heparin-binding growth factors for alveolar type II cells in fibroblast-conditioned medium by PANOS, R. J, RUBIN, J. S, AARONSON, S. A, MASON, R. J

“…Epithelial-mesenchymal interactions mediate aspects of normal lung growth and development and are important in the restoration of normal alveolar architecture…”
Get full text

Growth factor/matrix-induced proliferation of human adult beta-cells by Hayek, A., Beattie, G. M., Cirulli, V., Lopez, A. D., Ricordi, C., Rubin, J. S.

“…Growth factor/matrix-induced proliferation of human adult beta-cells. A Hayek , G M Beattie , V Cirulli , A D Lopez , C Ricordi and J S Rubin Whittier…”
Get full text

Purification and Characterization of a Newly Identified Growth Factor Specific for Epithelial Cells by Rubin, Jeffrey S., Osada, Hiroyuki, Finch, Paul W., Taylor, William G., Rudikoff, Stuart, Aaronson, Stuart A.

“…A growth factor specific for epithelial cells was identified in conditioned medium of a human embryonic lung fibroblast cell line, The factor, provisionally…”
Get full text

Laryngeal Manual Therapy: A Preliminary Study to Examine its Treatment Effects in the Management of Muscle Tension Dysphonia by Mathieson, L, Hirani, S.P, Epstein, R, Baken, R.J, Wood, G, Rubin, J.S

“…Summary The objectives of this study were to determine appropriate acoustic and outcome measures for the evaluation of a method of laryngeal manual therapy…”
Get full text