Search Results - "Rubin, G. M."
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Evaluation of two, commercial, multi-dye, nucleic acid amplification technology tests, for HBV/HCV/HIV-1/HIV-2 and B19V/HAV, for screening blood and plasma for further manufacture
Published in Vox sanguinis (01-01-2013)“…Background The cobas® TaqScreen MPX Test, version 2.0, a multiplex, multi‐dye nucleic acid amplification technology (NAT) test from Roche was evaluated by two…”
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Analysis of genetic mosaics in developing and adult Drosophila tissues
Published in Development (Cambridge) (01-04-1993)“…We have constructed a series of strains to facilitate the generation and analysis of clones of genetically distinct cells in developing and adult tissues of…”
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exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster. The Adh region
Published in Genetics (Austin) (01-09-1999)“…A contiguous sequence of nearly 3 Mb from the genome of Drosophila melanogaster has been sequenced from a series of overlapping P1 and BAC clones. This region…”
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An expectation maximization algorithm for training hidden substitution models
Published in Journal of molecular biology (12-04-2002)“…We derive an expectation maximization algorithm for maximum-likelihood training of substitution rate matrices from multiple sequence alignments. The algorithm…”
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Expression of baculovirus P35 prevents cell death in Drosophila
Published in Development (Cambridge) (01-08-1994)“…The baculovirus P35 protein functions to prevent apoptotic death of infected cells. We have expressed P35 in the developing embryo and eye of the fly…”
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Determination of neuronal cell fate : lessons from the R7 neuron of Drosophila
Published in Annual review of neuroscience (01-01-1994)“…(DBO)…”
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KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis
Published in Science (American Association for the Advancement of Science) (30-08-1996)“…During neurogenesis in Drosophila both neurons and nonneuronal cells are produced from a population of initially equivalent cells. The kuzbanian (kuz) gene…”
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A Misexpression Screen Identifies Genes That Can Modulate RAS1 Pathway Signaling in Drosophila melanogaster
Published in Genetics (Austin) (01-11-2000)“…Differentiation of the R7 photoreceptor cell is dependent on the Sevenless receptor tyrosine kinase, which activates the RAS1/mitogen-activated protein kinase…”
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The TGF beta homolog dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina
Published in Cell (03-12-1993)“…Development of the Drosophila retina occurs asynchronously; differentiation, its front marked by the morphogenetic furrow, progresses across the eye disc…”
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Gene Disruptions Using P Transposable Elements: An Integral Component of the Drosophila Genome Project
Published in Proceedings of the National Academy of Sciences - PNAS (21-11-1995)“…Biologists require genetic as well as molecular tools to decipher genomic information and ultimately to understand gene function. The Berkeley Drosophila…”
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dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila
Published in Development (Cambridge) (01-12-1994)“…Neural specification and differentiation in the Drosophila eye sweep across the unpatterned epithelial monolayer of the eye imaginal disc following a…”
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14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila
Published in Genes & development (01-05-1997)“…We have isolated mutations in the gene encoding a Drosophila 14-3-3 epsilon protein as suppressors of the rough eye phenotype caused by the ectopic expression…”
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KSR modulates signal propagation within the MAPK cascade
Published in Genes & development (01-11-1996)“…Kinase suppressor of Ras (KSR) is a recently identified component of Ras-dependent signaling pathways. In this report, we show that murine KSR1 (mKSR1)…”
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The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins
Published in Cell (06-05-1994)“…We have identified a Drosophila gene, peanut (pnut), that is related in sequence to the CDC3, CDC10, CDC11, and CDC12 genes of S. cerevisiae. These genes are…”
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A new brain dopamine‐deficient Drosophila and its pharmacological and genetic rescue
Published in Genes, brain and behavior (01-03-2017)“…Dopamine (DA) is a neurotransmitter with conserved behavioral roles between invertebrate and vertebrate animals. In addition to its neural functions, in…”
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Isolation and expression of scabrous, a gene regulating neurogenesis in Drosophila
Published in Genes & development (01-11-1990)“…Mutations in the Drosophila scabrous (sca) gene affect eye and bristle development, leading to irregular spacing of ommatidia and bristle duplications in the…”
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Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase
Published in Cell (15-11-1991)“…We have conducted a genetic screen for mutations that decrease the effectiveness of signaling by a protein tyrosine kinase, the product of the Drosophila…”
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Drosophila and human RecQ5 exist in different isoforms generated by alternative splicing
Published in Nucleic acids research (15-09-1999)“…Members of the RecQ helicase superfamily have been implicated in DNA repair, recombination and replication. Although the genome of the budding yeast…”
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A Genetic Screen for Modifiers of a Kinase Suppressor of Ras-Dependent Rough Eye Phenotype in Drosophila
Published in Genetics (Austin) (01-11-2000)“…kinase suppressor of Ras (ksr) encodes a putative protein kinase that by genetic criteria appears to function downstream of RAS in multiple receptor tyrosine…”
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A screen for genes that function downstream of Ras1 during Drosophila eye development
Published in Genetics (Austin) (01-05-1996)“…Cell-fate specification of the R7 photoreceptor cell is controlled by the sevenless receptor tyrosine kinase (SevRTK) and Ras1, the Drosophila homologue of…”
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