Search Results - "Ruberto, A."

Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles by Eaton, John K., Furst, Laura, Ruberto, Richard A., Moosmayer, Dieter, Hilpmann, André, Ryan, Matthew J., Zimmermann, Katja, Cai, Luke L., Niehues, Michael, Badock, Volker, Kramm, Anneke, Chen, Sixun, Hillig, Roman C., Clemons, Paul A., Gradl, Stefan, Montagnon, Claire, Lazarski, Kiel E., Christian, Sven, Bajrami, Besnik, Neuhaus, Roland, Eheim, Ashley L., Viswanathan, Vasanthi S., Schreiber, Stuart L.

“…We recently described glutathione peroxidase 4 (GPX4) as a promising target for killing therapy-resistant cancer cells via ferroptosis. The onset of therapy…”
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Microbial associations for bioremediation. What does “microbial consortia” mean? by Massot, Francisco, Bernard, Nathalie, Alvarez, Lucas M. Martinez, Martorell, María M., Mac Cormack, Walter P., Ruberto, Lucas A. M.

“…Microbial associations arise as useful tools in several biotechnological processes. Among them, bioremediation of contaminated environments usually takes…”
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Single-cell RNA sequencing reveals developmental heterogeneity among Plasmodium berghei sporozoites by Ruberto, Anthony A., Bourke, Caitlin, Merienne, Nicolas, Obadia, Thomas, Amino, Rogerio, Mueller, Ivo

“…In the malaria-causing parasite’s life cycle, Plasmodium sporozoites must travel from the midgut of a mosquito to the salivary glands before they can infect a…”
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Structural and functional comparison of SARS-CoV-2-spike receptor binding domain produced in Pichia pastoris and mammalian cells by Arbeitman, Claudia R., Auge, Gabriela, Blaustein, Matías, Bredeston, Luis, Corapi, Enrique S., Craig, Patricio O., Cossio, Leandro A., Dain, Liliana, D’Alessio, Cecilia, Elias, Fernanda, Fernández, Natalia B., Gándola, Yamila B., Gasulla, Javier, Gorojovsky, Natalia, Gudesblat, Gustavo E., Herrera, María G., Ibañez, Lorena I., Idrovo, Tommy, Rando, Matías Iglesias, Kamenetzky, Laura, Nadra, Alejandro D., Noseda, Diego G., Paván, Carlos H., Pavan, María F., Pignataro, María F., Roman, Ernesto, Ruberto, Lucas A. M., Rubinstein, Natalia, Santos, Javier, Velazquez, Francisco, Zelada, Alicia M.

“…The yeast Pichia pastoris is a cost-effective and easily scalable system for recombinant protein production. In this work we compared the conformation of the…”
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Single-cell RNA sequencing of Plasmodium vivax sporozoites reveals stage- and species-specific transcriptomic signatures by Ruberto, Anthony A., Bourke, Caitlin, Vantaux, Amélie, Maher, Steven P., Jex, Aaron, Witkowski, Benoit, Snounou, Georges, Mueller, Ivo

“…BACKGROUNDPlasmodium vivax sporozoites reside in the salivary glands of a mosquito before infecting a human host and causing malaria. Previous…”
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KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism by Ruberto, Anthony A, Gréchez-Cassiau, Aline, Guérin, Sophie, Martin, Luc, Revel, Johana S, Mehiri, Mohamed, Subramaniam, Malayannan, Delaunay, Franck, Teboul, Michèle

“…The mammalian circadian timing system and metabolism are highly interconnected, and disruption of this coupling is associated with negative health outcomes…”
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Single-cell RNA profiling of Plasmodium vivax-infected hepatocytes reveals parasite- and host- specific transcriptomic signatures and therapeutic targets by Ruberto, Anthony A., Maher, Steven P., Vantaux, Amélie, Joyner, Chester J., Bourke, Caitlin, Balan, Balu, Jex, Aaron, Mueller, Ivo, Witkowski, Benoit, Kyle, Dennis E.

“…The resilience of Plasmodium vivax , the most widely-distributed malaria-causing parasite in humans, is attributed to its ability to produce dormant liver…”
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Metagenomic strategies identify diverse integron‐integrase and antibiotic resistance genes in the Antarctic environment by Antelo, Verónica, Giménez, Matías, Azziz, Gastón, Valdespino‐Castillo, Patricia, Falcón, Luisa I., Ruberto, Lucas A. M., Mac Cormack, Walter P., Mazel, Didier, Batista, Silvia

“…The objective of this study is to identify and analyze integrons and antibiotic resistance genes (ARGs) in samples collected from diverse sites in terrestrial…”
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Development of a Cost-Effective Process for the Heterologous Production of SARS-CoV-2 Spike Receptor Binding Domain Using Pichia pastoris in Stirred-Tank Bioreactor by Noseda, Diego G., D’Alessio, Cecilia, Santos, Javier, Idrovo-Hidalgo, Tommy, Pignataro, Florencia, Wetzler, Diana E., Gentili, Hernán, Nadra, Alejandro D., Roman, Ernesto, Paván, Carlos, Ruberto, Lucas A. M.

“…SARS-CoV-2 was identified as the pathogenic agent causing the COVID-19 pandemic. Among the proteins codified by this virus, the Spike protein is one of the…”
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Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently by Eaton, John K, Ruberto, Richard A, Kramm, Anneke, Viswanathan, Vasanthi S, Schreiber, Stuart L

“…GPX4 represents a promising yet difficult-to-drug therapeutic target for the treatment of, among others, drug-resistant cancers. Although most GPX4 inhibitors…”
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Unraveling the intricacies of host-pathogen interaction through single-cell genomics by Gioacchino, Emanuele, Vandelannoote, Koen, Ruberto, Anthony A., Popovici, Jean, Cantaert, Tineke

“…Single-cell genomics provide researchers with tools to assess host-pathogen interactions at a resolution previously inaccessible. Transcriptome analysis,…”
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Antarctic wastewater: A local source of microplastic pollution by Bernard, Nathalie, Ruberto, Lucas A.M., Oberhaensli, François, Vodopivez, Cristian, Metian, Marc, Alonso-Hernandez, Carlos M.

“…Microplastic (MP) particles can be found all around the planet, even in Antarctica where they can be locally originated or transported by marine currents and…”
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Disparities in Telemedicine Utilization During COVID-19 Pandemic by Richard A. Ruberto, BA, Eric A. Schweppe, BS, Rifat Ahmed, MS, Hasani W. Swindell, MD, Christopher A. Cordero, MHA, Nathan S. Lanham, MD, Charles M. Jobin, MD

“…Background:. The coronavirus-19 (COVID-19) pandemic has prompted a shift in health-care provision toward implementation of telemedicine. This study…”
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MCD diet-induced steatohepatitis generates a diurnal rhythm of associated biomarkers and worsens liver injury in Klf10 deficient mice by Leclère, Pierre S., Rousseau, Déborah, Patouraux, Stéphanie, Guérin, Sophie, Bonnafous, Stéphanie, Gréchez-Cassiau, Aline, Ruberto, Anthony A., Luci, Carmelo, Subramaniam, Malayannan, Tran, Albert, Delaunay, Franck, Gual, Philippe, Teboul, Michèle

“…A large number of hepatic functions are regulated by the circadian clock and recent evidence suggests that clock disruption could be a risk factor for liver…”
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Purification and properties of glycerol-3-phosphate dehydrogenase from the liver of the hibernating ground squirrel, Urocitellus richardsonii by Ruberto, Anthony A., Childers, Christine L., Storey, Kenneth B.

“…Cytosolic glycerol-3-phosphate dehydrogenase (G3PDH, EC 1.1.1.8) is an important branch point enzyme connecting lipid metabolism and carbohydrate metabolism…”
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Sheptide A: an antimalarial cyclic pentapeptide from a fungal strain in the Herpotrichiellaceae by Shepherd, Robert A., Earp, Cody E., Cank, Kristof B., Raja, Huzefa A., Burdette, Joanna, Maher, Steven P., Marin, Adriana A., Ruberto, Anthony A., Mai, Sarah Lee, Darveaux, Blaise A., Kyle, Dennis E., Pearce, Cedric J., Oberlies, Nicholas H.

“…As part of ongoing efforts to isolate biologically active fungal metabolites, a cyclic pentapeptide, sheptide A ( 1 ), was discovered from strain MSX53339 (…”
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Studies toward the comprehension of fungal-macroalgae interaction in cold marine regions from a biotechnological perspective by Martorell, M.M., Lannert, M., Matula, C.V., Quartino, M.L., de Figueroa, L.I.C., Cormack, WP Mac, Ruberto, L.A.M.

“…In marine ecosystems, macroalgae are the habitat for several microorganisms, fungi being among them. In the Antarctic benthic coastal ecosystem, macroalgae…”
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Covalent coupling of Spike’s receptor binding domain to a multimeric carrier produces a high immune response against SARS-CoV-2 by Berguer, Paula M., Blaustein, Matías, Bredeston, Luis M., Craig, Patricio O., D’Alessio, Cecilia, Elias, Fernanda, Farré, Paola C., Fernández, Natalia B., Gentili, Hernán G., Gándola, Yamila B., Gasulla, Javier, Gudesblat, Gustavo E., Herrera, María G., Ibañez, Lorena I., Idrovo-Hidalgo, Tommy, Nadra, Alejandro D., Noseda, Diego G., Paván, Carlos H., Pavan, María F., Pignataro, María F., Roman, Ernesto A., Ruberto, Lucas A. M., Rubinstein, Natalia, Sanchez, María V., Santos, Javier, Wetzler, Diana E., Zelada, Alicia M.

“…The receptor binding domain (RBD) of the Spike protein from SARS-CoV-2 is a promising candidate to develop effective COVID-19 vaccines since it can induce…”
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Disparities in Telemedicine Utilization During COVID-19 Pandemic: Analysis of Demographic Data from a Large Academic Orthopaedic Practice by Ruberto, Richard A., Schweppe, Eric A., Ahmed, Rifat, Swindell, Hasani W., Cordero, Christopher A., Lanham, Nathan S., Jobin, Charles M.

“…The coronavirus-19 (COVID-19) pandemic has prompted a shift in health-care provision toward implementation of telemedicine. This study investigated demographic…”
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Author Correction: Covalent coupling of Spike’s receptor binding domain to a multimeric carrier produces a high immune response against SARS-CoV-2 by Berguer, Paula M., Blaustein, Matías, Bredeston, Luis M., Craig, Patricio O., D’Alessio, Cecilia, Elias, Fernanda, Farré, Paola C., Fernández, Natalia B., Gentili, Hernán G., Gándola, Yamila B., Gasulla, Javier, Gudesblat, Gustavo E., Herrera, María G., Ibañez, Lorena I., Idrovo-Hidalgo, Tommy, Nadra, Alejandro D., Noseda, Diego G., Paván, Carlos H., Pavan, María F., Pignataro, María F., Roman, Ernesto A., Ruberto, Lucas A. M., Rubinstein, Natalia, Sanchez, María V., Santos, Javier, Wetzler, Diana E., Zelada, Alicia M.

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