Search Results - "Ruani FERNANDO"

Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway by Fernando, Ruani N., Cotter, Laurent, Perrin-Tricaud, Claire, Berthelot, Jade, Bartolami, Sylvain, Pereira, Jorge A., Gonzalez, Sergio, Suter, Ueli, Tricaud, Nicolas

“…Fast nerve conduction relies on successive myelin segments that electrically isolate axons. Segment geometry—diameter and length—is critical for the…”
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In vivo introduction of transgenes into mouse sciatic nerve cells in situ using viral vectors by Gonzalez, Sergio, Fernando, Ruani N, Perrin-Tricaud, Claire, Tricaud, Nicolas

“…The myelin sheath is essential for the rapid and efficient propagation of action potentials. However, our understanding of the basic molecular mechanisms that…”
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Cell cycle restriction by histone H2AX limits proliferation of adult neural stem cells by Fernando, Ruani N., Eleuteri, Boris, Abdelhady, Shaimaa, Nussenzweig, Andre, Andäng, Michael, Ernfors, Patrik, Rakic, Pasko

“…Adult neural stem, cell proliferation is dynamic and has the potential for massive self-renewal yet undergoes limited cell division in vivo. Here, we report an…”
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In Vivo Introduction of Transgenes into Mouse Sciatic Nerve Cells Using Viral Vectors by Van Hameren, Gerben, Gonzalez, Sergio, Fernando, Ruani N, Perrin-Tricaud, Claire, Tricaud, Nicolas

“…Myelinated fibers are essential for the rapid and efficient propagation of nerve information throughout the body. These fibers result from an intimate…”
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Dopaminergic neurons of system xc–‐deficient mice are highly protected against 6‐hydroxydopamine‐induced toxicity by Massie, Ann, Schallier, Anneleen, Kim, Seong Woong, Fernando, Ruani, Kobayashi, Sho, Beck, Heike, Bundel, Dimitri De, Vermoesen, Katia, Bannai, Shiro, Smolders, Ilse, Conrad, Marcus, Plesnila, Nikolaus, Sato, Hideyo, Michotte, Yvette

“…ABSTRACT Malfunctioning of system xc–, responsible for exchanging intracellular glutamate for extracellular cystine, can cause oxidative stress and…”
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The insulin-regulated aminopeptidase IRAP is colocalised with GLUT4 in the mouse hippocampus - potential role in modulation of glucose uptake in neurones? by Fernando, Ruani N., Albiston, Anthony L., Chai, Siew Y.

“…It is proposed that insulin‐regulated aminopeptidase (IRAP) is the site of action of two peptides, angiotensin IV and LVV‐hemorphin 7, which have facilitatory…”
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Blocking mitochondrial calcium release in Schwann cells prevents demyelinating neuropathies by Gonzalez, Sergio, Berthelot, Jade, Jiner, Jennifer, Perrin-Tricaud, Claire, Fernando, Ruani, Chrast, Roman, Lenaers, Guy, Tricaud, Nicolas

“…Schwann cells produce myelin sheath around peripheral nerve axons. Myelination is critical for rapid propagation of action potentials, as illustrated by the…”
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Identification and development of specific inhibitors for insulin‐regulated aminopeptidase as a new class of cognitive enhancers by Albiston, Anthony L, Diwakarla, Shanti, Fernando, Ruani N, Mountford, Simon J, Yeatman, Holly R, Morgan, Broden, Pham, Vi, Holien, Jessica K, Parker, Michael W, Thompson, Philip E, Chai, Siew Yeen

“…Two structurally distinct peptides, angiotensin IV and LVV‐haemorphin 7, both competitive high‐affinity inhibitors of insulin‐regulated aminopeptidase (IRAP),…”
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Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase by Albiston, Anthony L, Morton, Craig J, Ng, Hooi Ling, Pham, Vi, Yeatman, Holly R, Ye, Siying, Fernando, Ruani N, De Bundel, Dimitri, Ascher, David B, Mendelsohn, Frederick A.O, Parker, Michael W, Chai, Siew Yeen

“…Approximately one-quarter of people over the age of 65 are estimated to suffer some form of cognitive impairment, underscoring the need for effective…”
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Localization of cholesterol, amyloid and glia in Alzheimer’s disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and immunofluorescence imaging by Solé-Domènech, Santiago, Sjövall, Peter, Vukojević, Vladana, Fernando, Ruani, Codita, Alina, Salve, Sachin, Bogdanović, Nenad, Mohammed, Abdul H., Hammarström, Per, Nilsson, K. Peter R., LaFerla, Frank M., Jacob, Stefan, Berggren, Per-Olof, Giménez-Llort, Lydia, Schalling, Martin, Terenius, Lars, Johansson, Björn

“…The spatial distributions of lipids, amyloid-beta deposits, markers of neurons and glial cells were imaged, at submicrometer lateral resolution, in brain…”
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Interaction of the Akt Substrate, AS160, with the Glucose Transporter 4 Vesicle Marker Protein, Insulin-Regulated Aminopeptidase by Peck, Grantley R, Ye, Siying, Pham, Vi, Fernando, Ruani N, Macaulay, S. Lance, Chai, Siew Yeen, Albiston, Anthony L

“…Insulin-regulated aminopeptidase (IRAP), a marker of glucose transporter 4 (GLUT4) storage vesicles (GSVs), is the only protein known to traffic with GLUT4. In…”
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Gene knockout of insulin-regulated aminopeptidase: Loss of the specific binding site for angiotensin IV and age-related deficit in spatial memory by Albiston, Anthony L., Fernando, Ruani N., Yeatman, Holly R., Burns, Peta, Ng, Leelee, Daswani, Dina, Diwakarla, Shanti, Pham, Vi, Chai, Siew Yeen

“…The AT 4 ligands, angiotensin IV and LVV-hemorphin 7, elicit robust effects on facilitating memory by binding to a specific site in the brain historically…”
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Distribution and cellular localization of insulin-regulated aminopeptidase in the rat central nervous system by Fernando, Ruani N., Larm, Jari, Albiston, Anthony L., Chai, Siew Yeen

“…Central infusions of angiotensin IV enhance spatial learning, memory retention and retrieval, neurotransmitter release, and long‐term potentiation via…”
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Distinct distribution of GLUT4 and insulin regulated aminopeptidase in the mouse kidney by Albiston, Anthony L., Yeatman, Holly R., Pham, Vi, Fuller, Stephanie J., Diwakarla, Shanti, Fernando, Ruani N., Chai, Siew Yeen

“…The physiological importance of the insulin responsive glucose transporter GLUT4 in adipocytes and muscle in maintaining glucose homeostasis is well…”
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Sub‐cellular localization of insulin‐regulated membrane aminopeptidase, IRAP to vesicles in neurons by Fernando, Ruani N., Luff, Susan E., Albiston, Anthony L., Chai, Siew Yeen

“…Angiotensin IV and LVV‐hemorphin 7 promote robust enhancing effects on learning and memory. These peptides are also competitive inhibitors of the…”
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“Watching the Detectives” report of the general assembly of the EU project DETECTIVE Brussels, 24–25 November 2015 by Fernando, Ruani N., Chaudhari, Umesh, Escher, Sylvia E., Hengstler, Jan G., Hescheler, Jürgen, Jennings, Paul, Keun, Hector C., Kleinjans, Jos C. S., Kolde, Raivo, Kollipara, Laxmikanth, Kopp-Schneider, Annette, Limonciel, Alice, Nemade, Harshal, Nguemo, Filomain, Peterson, Hedi, Prieto, Pilar, Rodrigues, Robim M., Sachinidis, Agapios, Schäfer, Christoph, Sickmann, Albert, Spitkovsky, Dimitry, Stöber, Regina, van Breda, Simone G. J., van de Water, Bob, Vivier, Manon, Zahedi, René P., Vinken, Mathieu, Rogiers, Vera

“…SEURAT-1 is a joint research initiative between the European Commission and Cosmetics Europe aiming to develop in vitro- and in silico - based methods to…”
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Sub-cellular localization of insulin-regulated membrane aminopeptidase, IRAP to vesicles in neurons by FERNANDO, Ruani N, LUFF, Susan E, ALBISTON, Anthony L, SIEW YEEN CHAI

“…Angiotensin IV and LVV-hemorphin 7 promote robust enhancing effects on learning and memory. These peptides are also competitive inhibitors of the…”
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Alzheimer's, Angiotensin IV and an Aminopeptidase by Albiston, Anthony Lloyd, Fernando, Ruani, Ye, Siying, Peck, Grantley Ross, Chai, Siew Yeen

“…The angiotensin AT4 receptor was originally defined as the specific, high affinity binding site for the hexapeptide angiotensin IV (Ang IV). Subsequently, the…”
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Alzheimer's, Angiotensin IV and an Aminopeptidase by Anthony Lloyd ALBISTON, Ruani FERNANDO, Siying YE, Grantley Ross PECK, Siew Yeen CHAI

“…The angiotensin AT4 receptor was originally defined as the specific, high affinity binding site for the hexapeptide angiotensin IV (Ang IV). Subsequently, the…”
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Human skin stem cell-derived hepatic cells as in vitro drug discovery model for insulin-driven de novo lipogenesis by Buyl, Karolien, Vrints, Martine, Fernando, Ruani, Desmae, Terry, Van Eeckhoutte, Thomas, Jans, Mia, Van Der Schueren, Jan, Boeckmans, Joost, Rodrigues, Robim M., De Boe, Veerle, Rogiers, Vera, De Kock, Joery, Beirinckx, Filip, Vanhaecke, Tamara

“…Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is characterized by intrahepatic…”
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