Search Results - "Ruane O'Hora, Therese"

The peptide neuromedin U (NMU) is elevated in NYHA II and III heart failure by Healy, Vincent, O'Hora, Therese Ruane, Markos, Farouk

“…Aims Currently, there is no reliable biomarker to detect pre‐heart failure in humans. An early risk signal is an elevated left atrial pressure (LAP) and…”
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What is the mechanism of flow-mediated arterial dilatation by Markos, Farouk, Ruane O'Hora, Therese, Noble, Mark IM

“…Summary The present review attempts to explain the controversies concerning the mechanism of shear stress‐mediated arterial dilatation, commonly called…”
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Small and intermediate Ca2+-sensitive K+ channels do not play a role in vascular conductance during resting blood flow in the anaesthetised pig by Ruane-O’Hora, Therese, Markos, Farouk

“…Flow-induced dilation in resistance arteries is mediated by endothelium-dependent hyperpolarisation via small and intermediate conducting Ca 2+ sensitive K +…”
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The vascular glycocalyx is not a mechanosensor in conduit arteries in the anesthetized pig by Ruane-O'Hora, Therese, Ahmeda, Ahmad, Markos, Farouk

“…The role of the glycocalyx as the endothelial sensor of an increase in blood flow was assessed in the iliac artery in vivo. Acetylcholine-induced flow mediated…”
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Effect of clazosentan, a selective endothelin A receptor antagonist, and tezosentan, a dual endothelin A/B antagonist, on pulsatile shear stress induced constriction of the iliac in the anaesthetized pig by Ruane-O'Hora, Therese, Rae, Mark George, Markos, Farouk

“…Summary 1. The effects of changes in mean and pulsatile shear stress on the diameter of the iliac of the anaesthetized pig were investigated in the presence of…”
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Platelets Do Not Alter Flow-Mediated Dilation or Arterial Conduction in vivo by Ruane-O'Hora, Therese, Markos, Farouk

“…The aim of this study was to investigate whether platelets contribute to shear stress and vascular conductance in the iliac vascular bed in vivo. Flow-mediated…”
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A novel lipid-based solid dispersion for enhancing oral bioavailability of Lycopene – In vivo evaluation using a pig model by Faisal, Waleed, Ruane-O’Hora, Therese, O’Driscoll, Caitriona M., Griffin, Brendan T.

“…Lycopene is a potent anti-oxidant, which has been widely reported for its potential benefits at reducing the risks of certain types of cancer e.g. prostate…”
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Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments by O’Shea, Joseph P., Faisal, Waleed, Ruane-O’Hora, Therese, Devine, Ken J., Kostewicz, Edmund S., O’Driscoll, Caitriona M., Griffin, Brendan T.

“…[Display omitted] Novel formulations that overcome the solubility limitations of poorly water soluble drugs (PWSD) are becoming ever more critical to a drug…”
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Small and intermediate Ca 2+ -sensitive K + channels do not play a role in vascular conductance during resting blood flow in the anaesthetised pig by Ruane-O'Hora, Therese, Markos, Farouk

“…Flow-induced dilation in resistance arteries is mediated by endothelium-dependent hyperpolarisation via small and intermediate conducting Ca sensitive K…”
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Intraluminal hyperglycaemia causes conduit and resistance artery dilatation and inhibits vascular autoregulation in the anaesthetised pig by Ruane-O'Hora, Therese, Shortt, Christine M, Edge, Deirdre, Markos, Farouk, Noble, Mark I M

“…The effect of intraluminal hyperglycaemia was investigated in the iliac artery of 11 anaesthetised pigs. Following isolation of a test segment, hyperglycaemic…”
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The effect of alphaxalone-alphadolone, propofol, and pentobarbitone anaesthesia on the β-endorphin and ACTH response to haemorrhage in the pig by Ruane-O'Hora, Therese, Hall, W J, Markos, F

“…In the literature there appears to be variability in reported levels of certain hormones during haemorrhage, specifically adrenocorticotrophic hormone (ACTH)…”
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Effect of clazosentan, a selective endothelin A receptor antagonist, and tezosentan, a dual endothelin A/B antagonist, on pulsatile shear stress induced constriction of the iliac in the anaesthetized pig: Endothelin antagonists and shear stress by Ruane-O’Hora, Therese, Rae, Mark George, Markos, Farouk

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