Search Results - "Ruan, Yuxia"
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Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia
Published in Nature communications (14-01-2019)“…Under hypoxia, most of glucose is converted to secretory lactate, which leads to the overuse of glutamine-carbon. However, under such a condition how glutamine…”
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Trends and efficacy of omitting axillary lymph node dissection in early‐stage male breast cancer with limited nodal involvement: A population‐based cohort study
Published in Cancer medicine (Malden, MA) (01-10-2024)“…Background The effectiveness of sentinel lymph node biopsy (SLNB) versus axillary lymph node dissection (ALND) in managing early‐stage male breast cancer (MBC)…”
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3
Curcumin induced HepG2 cell apoptosis-associated mitochondrial membrane potential and intracellular free Ca²⁺ concentration
Published in European journal of pharmacology (01-01-2011)“…Curcumin is a phytochemicals which is able to inhibit carcinogenesis in a variety of cell lines. However little is known about its effect on the cell-surface…”
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4
NREP, transcriptionally upregulated by HIF-1α, aggravates breast cancer cell growth and metastasis by promoting glycolysis
Published in Cell death discovery (02-05-2024)“…Breast cancer (BC) poses a great threat to women’s health. Neuronal regeneration related protein (NREP) is a multifunctional protein that is involved in…”
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5
Assessment of the impact of residual tumors at different sites post-neoadjuvant chemotherapy on prognosis in breast cancer patients and development of a disease-free survival prediction model
Published in Therapeutic advances in medical oncology (01-01-2024)“…Residual disease after neoadjuvant chemotherapy (NAC) in breast cancer patients predicts worse outcomes than pathological complete response. Differing…”
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Identification of a novel glycolysis-related prognosis risk signature in triple-negative breast cancer
Published in Frontiers in oncology (18-05-2023)“…Triple-negative breast cancer (TNBC) is a particularly aggressive cluster of breast cancer characterized by significant molecular heterogeneity. Glycolysis is…”
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PKM2 promotes reductive glutamine metabolism
Published in Cancer biology & medicine (01-11-2018)“…Pyruvate kinases M (PKM), including the PKM1 and PKM2 isoforms, are critical factors in glucose metabolism. PKM2 promotes aerobic glycolysis, a phenomenon…”
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Curcumin induced nanoscale CD44 molecular redistribution and antigen–antibody interaction on HepG2 cell surface
Published in Analytica chimica acta (04-07-2011)“…[Display omitted] ► In this study, we investigate the changes of CD44 expression and distribution on HepG2 cells after curcumin treatment. ► We find curcumin…”
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Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth
Published in The Journal of experimental medicine (02-03-2020)“…Cancer cells often proliferate under hypoxia and reprogram their metabolism. However, how to find targets to effectively block the hypoxia-associated metabolic…”
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10
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells
Published in Molecular therapy (08-04-2020)“…Caspase-8, a well-characterized initiator of apoptosis, has also been found to play non-apoptotic roles in cells. In this study, we reveal that caspase-8 can…”
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11
Curcumin induced HepG2 cell apoptosis-associated mitochondrial membrane potential and intracellular free Ca(2+) concentration
Published in European journal of pharmacology (10-01-2011)“…Curcumin is a phytochemicals which is able to inhibit carcinogenesis in a variety of cell lines. However little is known about its effect on the cell-surface…”
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12
Effect of the HER-2/CEP17 ratio in IHC 2+/FISH-amplified breast cancer on pathological complete response to neoadjuvant pertuzumab and trastuzumab treatment-a retrospective cohort study
Published in Gland surgery (01-12-2022)“…Human epidermal growth factor receptor-2 (HER-2) protein expression level could serve as a predictor of pathological complete response (pCR) to neoadjuvant…”
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13
Curcumin induced HepG2 cell apoptosis-associated mitochondrial membrane potential and intracellular free Ca 2+ concentration
Published in European journal of pharmacology (2011)“…Curcumin is a phytochemicals which is able to inhibit carcinogenesis in a variety of cell lines. However little is known about its effect on the cell-surface…”
Get full text
Journal Article