Search Results - "Ruan, Merry Z C"

Clinical exome sequencing for inherited retinal degenerations at a tertiary care center by Ganapathi, Mythily, Thomas-Wilson, Amanda, Buchovecky, Christie, Dharmadhikari, Avinash, Barua, Subit, Lee, Winston, Ruan, Merry Z. C., Soucy, Megan, Ragi, Sara, Tanaka, Joy, Clark, Lorraine N., Naini, Ali B., Liao, Jun, Mansukhani, Mahesh, Tsang, Stephen, Jobanputra, Vaidehi

“…Inherited retinal degenerations are clinically and genetically heterogeneous diseases characterized by progressive deterioration of vision. This study aimed at…”
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Proteoglycan 4 expression protects against the development of osteoarthritis by Ruan, Merry Z C, Erez, Ayelet, Guse, Kilian, Dawson, Brian, Bertin, Terry, Chen, Yuqing, Jiang, Ming-Ming, Yustein, Jason, Gannon, Francis, Lee, Brendan H L

“…Osteoarthritis (OA) is a common degenerative condition that afflicts more than 70% of the population between 55 and 77 years of age. Although its prevalence is…”
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Quantitative imaging of murine osteoarthritic cartilage by phase‐contrast micro–computed tomography by Ruan, Merry Z. C., Dawson, Brian, Jiang, Ming‐Ming, Gannon, Francis, Heggeness, Michael, Lee, Brendan H. L.

“…Objective The mouse is an optimal model organism in which gene–environment interactions can be used to study the pathogenesis of osteoarthritis (OA). The gold…”
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Eye and Orbit Injuries Caused by Electric Scooters and Hoverboards in the United States by Ruan, Merry Z C, Meer, Elana, Kaur, Gurbani, Namiri, Nikan K, Ashraf, Davin C, Winn, Bryan J, Kersten, Robert, Vagefi, M Reza, Grob, Seanna

“…To evaluate eye and orbital injuries in non-powered scooter, electric-scooter (e-scooter), and hoverboard riders in the United States (US) between 2014 and…”
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Viral Delivery Systems for CRISPR by Xu, Christine L, Ruan, Merry Z C, Mahajan, Vinit B, Tsang, Stephen H

“…The frontiers of precision medicine have been revolutionized by the development of Clustered Regularly-Interspaced Short Palindromic Repeats (CRISPR)/Cas9 as…”
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Eyecare provider attitudes toward and adoption of telehealth during the COVID-19 pandemic by Liu, Yingna, Ruan, Merry Z C, Haq, Zeeshan, Hwang, David G

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Disease‐Modifying Osteoarthritis Treatment With Interleukin‐1 Receptor Antagonist Gene Therapy in Small and Large Animal Models by Nixon, Alan J., Grol, Matthew W., Lang, Hayley M., Ruan, Merry Z. C., Stone, Adrianne, Begum, Laila, Chen, Yuqing, Dawson, Brian, Gannon, Francis, Plutizki, Stanislav, Lee, Brendan H. L., Guse, Kilian

“…Objective Gene therapy holds great promise for the treatment of osteoarthritis (OA) because a single intraarticular injection can lead to long‐term expression…”
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Combinatorial Prg4 and Il-1ra Gene Therapy Protects Against Hyperalgesia and Cartilage Degeneration in Post-Traumatic Osteoarthritis by Stone, Adrianne, Grol, Matthew W, Ruan, Merry Z C, Dawson, Brian, Chen, Yuqing, Jiang, Ming-Ming, Song, I-Wen, Jayaram, Prathap, Cela, Racel, Gannon, Francis, Lee, Brendan H L

“…Osteoarthritis (OA) is a degenerative disease of synovial joints characterized by progressive loss of articular cartilage, subchondral bone remodeling, and…”
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Retina Vascular Structures near the Optic Disc and in the Macula in Primary Angle-Closure Suspects by Pan, Xiaohua, Ruan, Merry Z.C., Fan, Wudi, Cao, Kai, Feng, Hui, Hu, Zhongyin, Yang, Yue, Yan, Fancheng, Zhao, Mengya, Liu, Qian, Fu, Min, Xiang, Fei, Lee, Richard, Li, Shuning, Han, Ying

“…Abstract Introduction: The main aim of this article was to study the retinal peripapillary and macular vascular structures in eyes with primary angle-closure…”
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Treatment of osteoarthritis using a helper-dependent adenoviral vector retargeted to chondrocytes by Ruan, Merry Zc, Cerullo, Vincenzo, Cela, Racel, Clarke, Chris, Lundgren-Akerlund, Evy, Barry, Michael A, Lee, Brendan Hl

“…Osteoarthritis (OA) is a joint disease characterized by degeneration of the articular cartilage, subchondral bone remodeling, and secondary inflammation. It is…”
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Utility of en-face imaging in diagnosis of occult macular dystrophy with RP1L1 mutation: A case series by Ruan, Merry Zc, Hussnain, S Amal, Thomas, Amanda, Mansukhani, Mahesh, Tsang, Stephen, Yannuzzi, Lawrence

“…To report imaging findings at the level of ellipsoid zone (EZ) in two cases of occult macular dystrophy (OMD) with retinitis pigmentosa 1-like 1 (RP1L1)…”
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Evaluating precision medicine approaches for gene therapy in patient-specific cellular models of Bietti crystalline dystrophy by Li, Yao, Yang, Richard R, Li, Yong-Shi, Hsu, Chun-Wei, Jenny, Laura A, Kong, Yang, Ruan, Merry Zc, Sparrow, Janet R, Tsang, Stephen H

“…Patient-specific induced pluripotent stem cell-derived (iPSC-derived) cell lines allow for therapies to be tailored to individual patients, increasing…”
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Pain, motor and gait assessment of murine osteoarthritis in a cruciate ligament transection model by Ruan, M.Z.C, Patel, R.M, Dawson, B.C, Jiang, M.-M, Lee, B.H.L

“…Summary Objective The major complaint of Osteoarthritis (OA) patients is pain. However, due to the nature of clinical studies and the limitation of animal…”
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