Search Results - "Ruan, Lingfei"
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Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression
Published in Cell research (01-10-2019)“…Recently, increasing evidence has suggested the association between gut dysbiosis and Alzheimer’s disease (AD) progression, yet the role of gut microbiota in…”
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Amyloid deposition and inflammation in APPswe/PS1dE9 mouse model of Alzheimer's disease
Published in Current Alzheimer research (01-12-2009)“…Alzheimer's disease (AD) is characterized by amyloid plaques and neurofibrillary tangles associated with chronic inflammation. APPswe/PS1dE9 is an AD mouse…”
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Resveratrol differentially modulates inflammatory responses of microglia and astrocytes
Published in Journal of neuroinflammation (17-08-2010)“…Inflammatory responses in the CNS mediated by activated glial cells play an important role in host-defense but are also involved in the development of…”
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The green tea polyphenol (−)-epigallocatechin-3-gallate inhibits leukocyte activation by bacterial formylpeptide through the receptor FPR
Published in International immunopharmacology (01-08-2009)“…Although green tea polyphenol catechin is considered as a potential anti-inflammatory agent, its effect on bacterial component-induced inflammation has been…”
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RNA interference as a novel and powerful tool in immunopharmacological research
Published in International immunopharmacology (01-04-2007)“…RNA interference (RNAi), as an evolutionarily conserved mechanism for silencing gene expression, is realized through the actions of both small interference RNA…”
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Norepinephrine promotes microglia to uptake and degrade amyloid beta peptide through upregulation of mouse formyl peptide receptor 2 and induction of insulin-degrading enzyme
Published in The Journal of neuroscience (01-09-2010)“…Locus ceruleus (LC) is the main subcortical site of norepinephrine synthesis. In Alzheimer's disease (AD) patients and rodent models, degeneration of LC…”
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The immunopharmacological properties of transforming growth factor beta
Published in International immunopharmacology (01-12-2005)“…Transforming growth factor-β (TGF-β) family members are multifunctional molecules, which play pivotal roles in regulating cell proliferation, differentiation,…”
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Norepinephrine Promotes Microglia to Uptake and Degrade Amyloid b Peptide through Upregulation of Mouse Formyl Peptide Receptor 2 and Induction of Insulin-Degrading Enzyme
Published in The Journal of neuroscience (01-09-2010)“…Locus ceruleus (LC) is the main subcortical site of norepinephrine synthesis. In Alzheimer's disease (AD) patients and rodent models, degeneration of LC…”
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Norepinephrine promotes microglia to uptake and clearance of amyloid β peptide through upregulation of mFPR2 and induction of neprilysin
Published in Alzheimer's & dementia (01-07-2010)Get full text
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Chemoattractants and receptors in Alzheimer's disease
Published in Frontiers in bioscience (Scholar edition) (01-01-2010)“…Chemoattractants, including classical chemoattractants and chemokines, are mediators of leukocyte trafficking in physiological immunosurveillance as well as…”
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Biologically active peptides interacting with the G protein-coupled formylpeptide receptor
Published in Protein and peptide letters (2007)“…Leucocytes accumulate at sites of inflammation and microbial infection in response to locally produced chemotactic factors. N-formylpeptides produced by Gram…”
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Brief review: The immunopharmacological properties of transforming growth factor beta
Published in International immunopharmacology (01-12-2005)“…Transforming growth factor- beta (TGF- beta ) family members are multifunctional molecules, which play pivotal roles in regulating cell proliferation,…”
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