Search Results - "Ruan, Jichen"
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Regulation of STAT5 phosphorylation and interaction with SHP1 by lnc-AC004893, a long non-coding RNA overexpressed in myeloproliferative neoplasms
Published in Hematology (Luxembourg) (01-12-2024)“…Constitutive activation of Janus kinase 2 (JAK2)/signal transducer and activator of transcription (STAT) signaling pathway is central to the pathogenesis of…”
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LMO family gene polymorphisms and Wilms tumor susceptibility in Chinese children: a five-center case-control study
Published in BMC cancer (27-06-2024)“…Wilms tumor is the most prevalent embryonal kidney malignancy in children worldwide. Previous genome-wide association study (GWAS) identified that LIM domain…”
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Association Between LIN28A Gene Polymorphisms and Glioma Susceptibility in Chinese Children
Published in Cancer control (2021)“…Gliomas are the most prevalent brain tumors among children and adolescents. The occurrence and development of various malignant tumors is closely related with…”
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Association of RAN and RANBP2 Gene Polymorphisms With Glioma Susceptibility in Chinese Children
Published in Cancer reports (01-07-2024)“…ABSTRACT Background Glioma is the most prevalent pediatric central nervous system malignancy. RAN, member RAS oncogene family (RAN), is a key signaling…”
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Association of m1A modification gene polymorphisms with glioma risk in Chinese children
Published in MedComm - Oncology (01-09-2023)“…Glioma is a highly heterogeneous malignancy with a high mortality rate and poor prognosis. m1A methylation modifications are associated with gliomagenesis…”
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Association of RNA m[sup.7]G Modification Gene Polymorphisms with Pediatric Glioma Risk
Published in BioMed research international (24-01-2023)Get full text
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Association of RNA m 7 G Modification Gene Polymorphisms with Pediatric Glioma Risk
Published in BioMed research international (2023)“…Glioma stemming from glial cells of the central nervous system (CNS) is one of the leading causes of cancer death in childhood. The genetic predisposition of…”
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Association of RNA m7G Modification Gene Polymorphisms with Pediatric Glioma Risk
Published in BioMed research international (01-01-2023)“…Glioma stemming from glial cells of the central nervous system (CNS) is one of the leading causes of cancer death in childhood. The genetic predisposition of…”
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Genetic variations in NER pathway gene polymorphisms and Wilms tumor risk: A six-center case-control study in East China
Published in IUBMB life (16-10-2024)“…The nucleotide excision repair (NER) system is one of the main ways to protect organisms from DNA damage caused by endogenous and exogenous carcinogens. NER…”
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Bortezomib suppresses self‐renewal and leukemogenesis of leukemia stem cell by NF‐ĸB‐dependent inhibition of CDK6 in MLL‐rearranged myeloid leukemia
Published in Journal of cellular and molecular medicine (01-03-2021)“…Acute myeloid leukaemia (AML) with chromosomal rearrangements involving the H3K4 methyltransferase mixed‐lineage leukaemia (MLL) is an aggressive subtype with…”
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NCDN is a Potential Biomarker and Therapeutic Target for Glioblastoma
Published in Journal of Cancer (2024)“…Glioblastoma (GBM) is a type of central nervous system malignancy. In our study, we determined the effect of in GBM patients through The Cancer Genome Atlas…”
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Investigation of the Relationship between CMYC Gene Polymorphisms and Glioma Susceptibility in Chinese Children
Published in Cancer investigation (26-11-2021)“…Glioma is a common central nervous system tumors in children. CMYC has a range of functions that are disrupted in various tumor cells, and may contribute to…”
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XPG rs17655 G>C polymorphism associated with cancer risk: evidence from 60 studies
Published in Aging (Albany, NY.) (20-05-2018)“…Xeroderma pigmentosum group G (XPG), a key component in nucleotide excision repair pathway, functions to cut DNA lesions during DNA repair. Genetic variations…”
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WT1 protein is cleaved by caspase-3 in apoptotic leukemic cells
Published in Leukemia & lymphoma (02-01-2018)“…The aberrant overexpression of Wilms' tumor-1 gene (WT1) plays an important role in blast cell survival and resistance to chemotherapy in acute myeloid…”
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YTHDF3 gene polymorphisms increase Wilms tumor risk in Chinese girls
Published in Journal of Cancer (01-01-2024)“…Wilms tumor is a prevalent pediatric tumor influenced by various genetic factors. m A modification is a common nucleotide modification that plays a role in a…”
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Association of m 1 A modification gene polymorphisms with glioma risk in Chinese children
Published in MedComm - Oncology (01-09-2023)“…Abstract Glioma is a highly heterogeneous malignancy with a high mortality rate and poor prognosis. m 1 A methylation modifications are associated with…”
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KRAS gene polymorphisms are associated with the risk of glioma: a two-center case-control study
Published in Translational pediatrics (01-03-2021)“…Glioma, also known as neuroglioma, is the most common primary tumors of the central nervous system. Many previous studies have reported associations between…”
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WDR4 gene polymorphisms and Wilms tumor susceptibility in Chinese children: A five-center case-control study
Published in Journal of Cancer (01-01-2023)“…Wilms tumor is the most common embryonal renal malignancy in children. WDR4 is an indispensable noncatalytic subunit of the RNA N7-methylguanosine (m7G)…”
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MYCN gene polymorphisms and Wilms tumor susceptibility in Chinese children
Published in Journal of clinical laboratory analysis (01-11-2019)“…Background Wilms tumor, derived from embryonic cells, accounts for a large proportion of pediatric renal tumors. MYCN encoded by MYCN proto‐oncogene, a member…”
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The association of miR34b/c and TP53 gene polymorphisms with Wilms tumor risk in Chinese children
Published in Bioscience reports (28-02-2020)“…Wilms tumor is the most common pediatric malignancy in the kidney. The miR34b/c is a downstream target gene of the transcription factor p53. The important role…”
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