Search Results - "Ruan, Chang Geng"

Bifunctional effect of the inflammatory cytokine tumor necrosis factor α on megakaryopoiesis and platelet production by Chu, Tiantian, Hu, Shuhong, Qi, Jiaqian, Li, Xueqian, Zhang, Xiang, Tang, Yaqiong, Yang, Meng, Xu, Yang, Ruan, Chang‐Geng, Han, Yue, Wu, De‐Pei

“…Background and Objectives Platelets are affected by many factors, such as infectious or aseptic inflammation, and different inflammatory states may induce…”
Get full text

Clinical significance of FLT3-ITD/CEBPA mutations and minimal residual disease in cytogenetically normal acute myeloid leukemia after hematopoietic stem cell transplantation by Wang, Hong, Li, Xue-Qian, Chu, Tian-Tian, Han, Shi-Yu, Qi, Jia-Qian, Tang, Ya-Qiong, Qiu, Hui-Ying, Fu, Cheng-Cheng, Tang, Xiao-Wen, Ruan, Chang-Geng, Wu, De-Pei, Han, Yue

“…Purpose Genetic changes have prognostic significance in cytogenetically normal acute myeloid leukemia (CN-AML). We set out to evaluate the prognostic of 6 gene…”
Get full text

Incidence, risk factors, and clinical significance of Epstein–Barr virus reactivation in myelodysplastic syndrome after allogeneic haematopoietic stem cell transplantation by Wang, Hong, Zhang, Tong-Tong, Qi, Jia-Qian, Chu, Tian-Tian, Miao, Miao, Qiu, Hui-Ying, Fu, Cheng-Cheng, Tang, Xiao-Wen, Ruan, Chang-Geng, Wu, De-Pei, Han, Yue

“…Epstein–Barr virus (EBV) reactivation is a life-threatening complication after allogeneic haematopoietic stem cell transplantation (allo-HSCT). In this study,…”
Get full text

Pyrosequencing quantified methylation level of miR-124 predicts shorter survival for patients with myelodysplastic syndrome by Wang, Hong, Zhang, Tong-Tong, Jin, Song, Liu, Hong, Zhang, Xiang, Ruan, Chang-Geng, Wu, De-Pei, Han, Yue, Wang, Xiao-Qin

“…Aberrant CpG island methylation has been increasingly recognized as a common event in myelodysplastic syndrome (MDS). To date, most of the previous studies of…”
Get full text

Efficacy of immunomodulatory therapy with all- trans retinoid acid in adult patients with chronic immune thrombocytopenia by Dai, Lan, Zhang, Ri, Wang, Zhaoyue, He, Yang, Bai, Xia, Zhu, Mingqing, Yu, Ziqiang, Ruan, Chang-geng

“…Abstract Introduction Immune thrombocytopenia (ITP) is a common hematologic disorder characterized by isolated thrombocytopenia. In adults, ITP is more likely…”
Get full text

Haploidentical allogeneic hematopoietic stem cell transplantation for thymoma-associated severe aplastic anemia: a case report by Lu, Cong, He, Guang-sheng, Jin, Song, Zhang, Xu-hui, Hu, Xiao-hui, Wu, De-pei, Sun, Ai-ning, Ruan, Chang-geng

Get more information

Significance of plasma von Willebrand factor level and von Willebrand factor-cleaving protease activity in patients with chronic renal diseases by Lu, Guo-yuan, Shen, Lei, Wang, Zhao-yue, Guo, Xiao-fang, Bai, Xia, Su, Jian, Ruan, Chang-geng

“…Background von Willebrand factor （vWF） mediates the initial capture of platelets to vascular subendothelium and is essential for platelet aggregation under…”
Get full text

Evaluation and clinical application of a new method for detecting ADAMTS13 activity by Wang, An-You, Dong, Ning-Zheng, Ma, Zhen-Ni, Zhang, Jing-Yu, Su, Jian, Ruan, Chang-Geng

“…Background A severe deficiency of ADAMTS13 activity contributes to the pathogenesis of thrombotic thrombocytopenic purpura （TTP）. Measuring the activity of…”
Get full text

Detection of autoantibodies against platelet glycoproteins in patients with immune thrombocytopenic purpura by flow cytometric immunobead array by He, Yang, Zhao, Yun-xiao, Zhu, Ming-qing, Wu, Qingyu, Ruan, Chang-geng

“…The goal of this study is to develop a flow cytometric immunobead array (FCIA) assay to detect platelet autoantibodies commonly present in bleeding patients…”
Get full text

Cathepsin L stimulates autophagy and inhibits apoptosis of ox-LDL-induced endothelial cells: Potential role in atherosclerosis by WEI, DANG-HENG, JIA, XIAO-YING, LIU, YANG-HUI, GUO, FENG-XIA, TANG, ZHI-HAN, LI, XIAO-HONG, WANG, ZUO, LIU, LU-SHAN, WANG, GUI-XUE, JIAN, ZHI-SHENG, RUAN, CHANG-GENG

“…The activation of endothelial cells by oxidized low-density lipoprotein (ox-LDL) with subsequent increases in endothelial permeability occurs in the early…”
Get full text

Anti-human VWF monoclonal antibody SZ-123 prevents arterial thrombus formation by inhibiting VWF–collagen and VWF–platelet interactions in Rhesus monkeys by Zhao, Yi-ming, Jiang, Miao, Ji, Shun-dong, He, Yang, Shen, Fei, Li, Xue-mei, Ruan, Chang-geng

“…(A) Closed conformation of A1-A2-A3. (B) Unfolded conformation of A1-A2-A3 induced by high shear. (C). SZ-123 inhibits interaction between VWF A3 and collagen,…”
Get full text

Effect of apolipoprotein A-I on ATP binding cassette transporter A1 degradation and cholesterol efflux in THP-1 macrophage-derived foam cells by Tang, Chao-Ke, Tang, Guo-Hua, Yi, Guang-Hui, Wang, Zuo, Liu, Lu-Shan, Wan, Shuang, Yuan, Zhong-Hua, He, Xiu-Sheng, Yang, Jun-Hao, Ruan, Chang-Geng, Yang, Yong-Zong

“…Cholesterol-loaded macrophage foam cells are a central component of atherosclerotic lesions. ATP binding cassette transporter A1 (ABCA1), the defective…”
Get full text

Clinical, pathological, and genetic analysis of ten patients with MYH9-related disease by Sun, Xiong-hua, Wang, Zhao-yue, Yang, Hai-yan, Cao, Li-juan, Su, Jian, Yu, Zi-qiang, Bai, Xia, Ruan, Chang-geng

“…MYH9-related disease (MYH9-RD) is an autosomal dominant disorder caused by mutations in the MYH9 gene. It is characterized by a triad of giant platelets,…”
Get more information

FLT3-ITD and CEBPA Mutations Predict Prognosis in Acute Myelogenous Leukemia Irrespective of Hematopoietic Stem Cell Transplantation by Wang, Hong, Chu, Tian-Tian, Han, Shi-Yu, Qi, Jia-Qian, Tang, Ya-Qiong, Qiu, Hui-Ying, Fu, Cheng-Cheng, Tang, Xiao-Wen, Ruan, Chang-Geng, Wu, De-Pei, Han, Yue

“…•Adverse karyotype, CEBPAmut, and FLT3-ITDmut were correlated with prognosis in acute myelogenous leukemia (AML).•Hematopoietic stem cell transplantation…”
Get full text

Recombinant Human Thrombopoietin Promotes Platelet Engraftment and Improves Prognosis of Patients with Myelodysplastic Syndromes and Aplastic Anemia after Allogeneic Hematopoietic Stem Cell Transplantation by Wang, Hong, Huang, Man, Zhao, Ying, Qi, Jia-Qian, Chen, Chun, Tang, Ya-Qiong, Qiu, Hui-Ying, Fu, Cheng-Cheng, Tang, Xiao-Wen, Wu, De-Pei, Ruan, Chang-Geng, Han, Yue

“…Highlights • Recombinant human thrombopoietin (rhTPO) promotes platelet engraftment in patients after allogeneic hematopoietic stem cell transplantation; • The…”
Get full text

Establishment of Double Antibody Sandwich ELISA for the Determination of Human Soluble VE-Cadherin in Human Plasma and Its Application by Ding, Jie, He, Yang, Yang, Jian-Feng, Zuo, Bin, Yang, Bing-Hua, Ruan, Chang-Geng

“…To establish double antibody sandwich enzyme-linked immunosorbent assay (ELISA) for the determination of human soluble VE-cadherin in human plasma and to…”
Get more information

Development of Hybridoma Cell Lines Secreting Monoclonal Antibodies against ADAMTS13 by Ling, Jing, Ma, Zhen-Ni, Yin, Jie, Shen, Fei, Xie, Li-Qian, Zhao, Yun-Xiao, Ruan, Chang-Geng

“…To establish the hybridoma cell lines secreting anti-ADAMTS13-T7 monoclonal antibodies (MA6) and to construct the MAb directed against different domains of…”
Get more information

Identification of Monoclonal Antibodies against von Willebrand Factor Cleaving Protease (ADAMTS13) and Their Function by Ma, Zhen-Ni, Ling, Jing, Shen, Fei, Xie, Li-Qian, Yin, Jie, Su, Jian, Ruan, Chang-Geng

“…To construct and identify the monoclonal antibodies against von willebrand factor cleaving protease(ADAMTS13), and to study their biological function. BALB/c…”
Get more information

THE ENHANCED GREEN FLUORESCENT PROTEIN AS A MARKER FOR HUMAN TUMOR CELLS LABELLED BY RETROVIRAL TRANSDUCTION by Fu, Jian-xin, Wang, Wei, Bai, Xia, Lu, Da-ru, Ruan, Chang-geng, Chen, Zi-xing

“…Objective: To investigate the feasibility of marking the human tumor cells with enhanced green fluorescent protein (EGFP) in vitro. Methods: The retroviral…”
Get full text

Influence of HSCT Preconditioning on ADAMTS-13 Activity and vWF level and Its Clinical Significance by Wang, Jie, Han, Yue, Hu, Lu-Ping, Wu, De-Pei, Ruan, Chang-Geng

“…To explore the influence of precondintioning on ADAMTS-13 activity and vWF level, and its clinical significance by measuring the alterations of ADAMTS-13…”
Get more information