Search Results - "Rütti, Sabine"

Low- and High-Density Lipoproteins Modulate Function, Apoptosis, and Proliferation of Primary Human and Murine Pancreatic β-Cells by Rütti, Sabine, Ehses, Jan A, Sibler, Rahel A, Prazak, Richard, Rohrer, Lucia, Georgopoulos, Spiros, Meier, Daniel T, Niclauss, Nadja, Berney, Thierry, Donath, Marc Y, von Eckardstein, Arnold

“…A low high-density lipoprotein (HDL) plasma concentration and the abundance of small dense low-density lipoproteins (LDL) are risk factors for developing type…”
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TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6 by Nackiewicz, Dominika, Dan, Meixia, He, Wei, Kim, Rosa, Salmi, Anisa, Rütti, Sabine, Westwell-Roper, Clara, Cunningham, Amanda, Speck, Madeleine, Schuster-Klein, Carole, Guardiola, Beatrice, Maedler, Kathrin, Ehses, Jan A.

“…Aims/hypothesis Inflammation contributes to pancreatic beta cell dysfunction in type 2 diabetes. Toll-like receptor (TLR)-2 and -4 ligands are increased…”
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Publisher Correction: Loss-of-function of the long non-coding RNA A830019P07Rik in mice does not affect insulin expression and secretion by Guay, Claudiane, Abdulkarim, Baroj, Tan, Jennifer Y., Dubuis, Gilles, Rütti, Sabine, Laybutt, David Ross, Widmann, Christian, Regazzi, Romano, Marques, Ana Claudia

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Expression, phosphorylation and function of the Rab-GTPase activating protein TBC1D1 in pancreatic beta-cells by Rütti, Sabine, Arous, Caroline, Nica, Alexandra C., Kanzaki, Makoto, Halban, Philippe A., Bouzakri, Karim

“…•TBC1D1 is expressed in human and rat beta-cells.•TBC1D1 is phosphorylated in response to glucose.•Knockdown of TBC1D1 resulted in increased basal and…”
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IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death by Rütti, Sabine, Howald, Cédric, Arous, Caroline, Dermitzakis, Emmanouil, Halban, Philippe A, Bouzakri, Karim

“…Abstract Objectives IL-13 is a cytokine classically produced by anti-inflammatory T-helper-2 lymphocytes; it is decreased in the circulation of type 2 diabetic…”
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Involvement of 4E-BP1 in the Protection Induced by HDLs on Pancreatic β-Cells by Pétremand, Jannick, Bulat, Natasa, Butty, Anne-Christine, Poussin, Carine, Rütti, Sabine, Au, Karin, Ghosh, Sujoy, Mooser, Vincent, Thorens, Bernard, Yang, Jiang-Yan, Widmann, Christian, Waeber, Gérard

“…High-density lipoproteins (HDLs) protect pancreatic β-cells against apoptosis. This property might relate to the increased risk to develop diabetes in patients…”
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Glucose-Dependent Insulinotropic Peptide Stimulates Glucagon-Like Peptide 1 Production by Pancreatic Islets via Interleukin 6, Produced by α Cells by Timper, Katharina, Dalmas, Elise, Dror, Erez, Rütti, Sabine, Thienel, Constanze, Sauter, Nadine S, Bouzakri, Karim, Bédat, Benoit, Pattou, Francois, Kerr-Conte, Julie, Böni-Schnetzler, Marianne, Donath, Marc Y

“…Background & Aims Glucose-dependent insulinotropic peptide (GIP) induces production of interleukin 6 (IL6) by adipocytes. IL6 increases production of…”
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Involvement of 4E-BP1 in the Protection Induced by HDLs on Pancreatic β-Cells by Pétremand, Jannick, Bulat, Natasa, Butty, Anne-Christine, Poussin, Carine, Rütti, Sabine, Au, Karin, Ghosh, Sujoy, Mooser, Vincent, Thorens, Bernard, Yang, Jiang-Yan, Widmann, Christian, Waeber, Gérard

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Circulating Follistatin Is Liver-Derived and Regulated by the Glucagon-to-Insulin Ratio by Hansen, Jakob S, Rutti, Sabine, Arous, Caroline, Clemmesen, Jens O, Secher, Niels H, Drescher, Andrea, Gonelle-Gispert, Carmen, Halban, Philippe A, Pedersen, Bente K, Weigert, Cora, Bouzakri, Karim, Plomgaard, Peter

“…Context: Follistatin is a plasma protein recently reported to increase under conditions with negative energy balance, such as exercise and fasting in humans…”
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Loss-of-function of the long non-coding RNA A830019P07Rik in mice does not affect insulin expression and secretion by Guay, Claudiane, Abdulkarim, Baroj, Tan, Jennifer Y., Dubuis, Gilles, Rütti, Sabine, Laybutt, David Ross, Widmann, Christian, Regazzi, Romano, Marques, Ana Claudia

“…Long non-coding RNAs (lncRNAs) contribute to diverse cellular functions and the dysregulation of their expression or function can contribute to diseases,…”
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In vitro proliferation of adult human beta-cells by Rutti, Sabine, Sauter, Nadine S, Bouzakri, Karim, Prazak, Richard, Halban, Philippe A, Donath, Marc Y

“…A decrease in functional beta-cell mass is a key feature of type 2 diabetes. Glucagon-like peptide 1 (GLP-1) analogues induce proliferation of rodent…”
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Are HDL receptors really located where we think they are in the liver? by Rütti, Sabine, Widmann, Christian

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Genetics and molecular biology: HDL plasticity and diversity of functions by Rütti, Sabine, Widmann, Christian

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Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα by Rutti, Sabine, Arous, Caroline, Schvartz, Domitille, Timper, Katharina, Sanchez, Jean-Charles, Dermitzakis, Emmanouil, Donath, Marc Y, Halban, Philippe A, Bouzakri, Karim

“…Abstract Objective We have previously shown the existence of a muscle–pancreas intercommunication axis in which CX3CL1 (fractalkine), a CX3C chemokine produced…”
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Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets by Lohmann, Christine, Schäfer, Nicola, von Lukowicz, Tobias, Sokrates Stein, M.A, Borén, Jan, Rütti, Sabine, Wahli, Walter, Donath, Marc Y, Lüscher, Thomas F, Matter, Christian M

“…Abstract Objective Atherosclerosis is a chronic inflammatory disease of major conduit arteries. Similarly, obesity and type 2 diabetes mellitus are associated…”
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Beta-Cell Function and Survival Are Modulated Differentially by Type I or Type II Muscle through Specific Myokines by MIZGIER, MARIA L., RUTTI, SABINE, PINGET, MICHEL, BOUZAKRI, KARIM

“…Type 2 diabetes has a complex pathophysiology implicating several organs as the adipose tissue the liver, the skeletal muscle and the pancreas. Tissue…”
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Angiogenin and Osteoprotegerin are type II muscle specific myokines protecting pancreatic beta-cells against proinflammatory cytokines by Rutti, Sabine, Dusaulcy, Rodolphe, Hansen, Jakob S., Howald, Cédric, Dermitzakis, Emmanouil T., Pedersen, Bente K., Pinget, Michel, Plomgaard, Peter, Bouzakri, Karim

“…Tissue cross-talk is emerging as a determinant way to coordinate the different organs implicated in glucose homeostasis. Among the inter-organ communication…”
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Large Granular Lymphocyte Expansion after Allogeneic Hematopoietic Stem Cell Transplant Is Associated with a Cytomegalovirus Reactivation and Shows an Indolent Outcome by Nann-Rütti, Sabine, Tzankov, Alexander, Cantoni, Nathan, Halter, Jörg, Heim, Dominik, Tsakiris, Dimitrios, Arber, Caroline, Buser, Andreas, Gratwohl, Alois, Tichelli, André, Rovó, Alicia

“…Expansions of CD3+ large granular lymphocytes (LGLs) after allogeneic hematopoietic stem cell transplantation (HSCT) have been described. We sought to evaluate…”
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