Search Results - "Rozov, Leonid A"

Asymmetric Synthesis of the Volatile Anesthetic 1,2,2,2-Tetrafluoroethyl Chlorofluoromethyl Ether Using a Stereospecific Decarboxylation of Unusual Stereochemical Outcome by Rozov, Leonid A, Rafalko, Patrice W, Evans, Suzanne M, Brockunier, Linda, Ramig, Keith

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Diisopropylethylamine mono(hydrogen fluoride) for nucleophilic fluorination of sensitive substrates: synthesis of sevoflurane by Kudzma, Linas V, Huang, Chialang G, Lessor, Ralph A, Rozov, Leonid A, Afrin, Syeda, Kallashi, Florida, McCutcheon, Conor, Ramig, Keith

“…Diisopropylethylamine mono(hydrogen fluoride) ( 8), which can be prepared by addition of two equivalents of diisopropylethylamine to the complex…”
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Preparation of the isoflurane enantiomers by Huang, Chialang G, Rozov, Leonid A, Halpern, Donald F, Vernice, Gerald G

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Acid fluorides and 1,1-difluoroethyl methyl ethers as new organic sources of fluoride for antimony pentachloride-catalyzed halogen-exchange reactions by Ramig, Keith, Kudzma, Linas V, Lessor, Ralph A, Rozov, Leonid A

“…1,1-Difluoroethyl methyl ethers such as the commercial veterinary anesthetic methoxyflurane (2,2-dichoro-1,1-difluoroethyl methyl ether, 6) decompose in the…”
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Asymmetric Synthesis of the Volatile Anesthetic 1,2,2,2-Tetrafluoroethyl Chlorofluoromethyl Ether Using a Stereospecific Decarboxylation of Unusual Stereochemical Outcome by Rozov, Leonid A, Rafalko, Patrice W, Evans, Suzanne M, Brockunier, Linda, Ramig, Keith

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Chiral interactions of the fluoroether anesthetics desflurane, isoflurane, enflurane, and analogues with modified cyclodextrins studied by capillary gas chromatography and nuclear magnetic resonance spectroscopy: A simple method for column-suitability screening by Ramig, Keith, Krishnaswami, Ashok, Rozov, Leonid A.

“…Eighteen chiral analogues of the chiral fluoroether anesthetics desflurane, isoflurane, and enflurane are synthesized and studied by capillary GC on four…”
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Enantioselective synthesis of the volatile anesthetic desflurane by Rozov, Leonid A., Huang, Chialang G., Halpern, Donald F., Vernice, Gerald G., Ramig, Keith

“…The first enantioselective synthesis of the commercial volatile anesthetic desflurane is reported. Treatment of ( R)-(−)-isoflurane with BrF 3 gives (…”
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The fluoromethyl ether sevoflurane as a fluoride source in halogen-exchange reactions by Rozov, Leonid A., Lessor, Ralph A., Kudzma, Linas V., Ramig, Keith

“…Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether (sevoflurane), fluoromethyl 1,1,2,3,3,3-hexafluoropropyl ether, and fluoromethyl…”
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New synthesis of (+)-(S)-halothane by Rozov, Leonid A., Ramig, Keith

“…A new synthesis of non‐racemic halothane (1‐bromo‐1‐chloro‐2,2,2‐trifluoroethane) is reported. The stereospecificity of the key reaction, decarboxylation of a…”
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Selective free-radical dechlorination of 1,1-dichloro-2,2,2-trifluoroethyl difluoromethyl ether initiated thermally or by uv light: A practical and ‘green’ method for isoflurane synthesis by Ramig, Keith, Quiroz, Fernando, Vernice, Gerald G., Rozov, Leonid A.

“…Treatment of 1,1-dichloro-2,2,2-trifluoroethyl difluoromethyl ether ( 3) with 2-propanol followed by either irradiation with UV light or heating with radical…”
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