Search Results - "Rozman, J."

Recent discoveries in dendritic cell tolerance-inducing pharmacological molecules by Švajger, Urban, Rožman, Primož J.

“…•Recent evidence points to increased diversity of Tol-DC characteristics.•Discovery of novel Tol-DC inducing agents will allow for advances in fine-tuning…”
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A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice by Ryan, D P, Henzel, K S, Pearson, B L, Siwek, M E, Papazoglou, A, Guo, L, Paesler, K, Yu, M, Müller, R, Xie, K, Schröder, S, Becker, L, Garrett, L, Hölter, S M, Neff, F, Rácz, I, Rathkolb, B, Rozman, J, Ehninger, G, Klingenspor, M, Klopstock, T, Wolf, E, Wurst, W, Zimmer, A, Fuchs, H, Gailus-Durner, V, Hrabě de Angelis, M, Sidiropoulou, K, Weiergräber, M, Zhou, Y, Ehninger, D

“…Dietary intake of methyl donors, such as folic acid and methionine, shows considerable intra-individual variation in human populations. While it is recognized…”
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Proximate causes for diet-induced obesity in laboratory mice: a case study by Kless, C, Rink, N, Rozman, J, Klingenspor, M

“…Background/Objectives: Detailed protocols and recommendations for the assessment of energy balance have been provided to address the problems associated with…”
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CD34+ enriched cell products intended for autologous transendocardial CD34+ cell transplantation release significant amounts of angiopoietin-1 by Rozman, J.-Z., Jez, M., Malicev, E., Krasna, M., Vrtovec, B., Cukjati, M., Rozman, P.

“…Cell-based therapy has emerged as a promising strategy for the treatment of patients with heart failure. Increasing evidence supports the hypothesis that…”
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Inflammation and mitochondrial fatty acid β-oxidation link obesity to early tumor promotion by Khasawneh, J, Schulz, M.D, Walch, A, Rozman, J, de Angelis, M. Hrabe, Klingenspor, M, Buck, A, Schwaiger, M, Saur, D, Schmid, R.M, Klöppel, G, Sipos, B, Greten, F.R, Arkan, M.C

“…Obesity is associated with increased risk for developing pancreatic cancer, and it is suggested that insulin resistance provides the missing link. Here we…”
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Peri-conceptional obesogenic exposure induces sex-specific programming of disease susceptibilities in adult mouse offspring by Dahlhoff, M., Pfister, S., Blutke, A., Rozman, J., Klingenspor, M., Deutsch, M.J., Rathkolb, B., Fink, B., Gimpfl, M., Hrabě de Angelis, M., Roscher, A.A., Wolf, E., Ensenauer, R.

“…Vulnerability of the fetus upon maternal obesity can potentially occur during all developmental phases. We aimed at elaborating longer-term health outcomes of…”
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Importing genetically altered animals: ensuring quality by Birling, M.-C., Fray, M. D., Kasparek, P., Kopkanova, J., Massimi, M., Matteoni, R., Montoliu, L., Nutter, L. M. J., Raspa, M., Rozman, J., Ryder, E. J., Scavizzi, F., Voikar, V., Wells, S., Pavlovic, G., Teboul, L.

“…The reproducibility of research using laboratory animals requires reliable management of their quality, in particular of their genetics, health and…”
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High fat diet-induced modifications in membrane lipid and mitochondrial-membrane protein signatures precede the development of hepatic insulin resistance in mice by Kahle, M, Schäfer, A, Seelig, A, Schultheiß, J, Wu, M, Aichler, M, Leonhardt, J, Rathkolb, B, Rozman, J, Sarioglu, H, Hauck, S.M, Ueffing, M, Wolf, E, Kastenmueller, G, Adamski, J, Walch, A, Hrabé de Angelis, M, Neschen, S

“…Abstract Objective Excess lipid intake has been implicated in the pathophysiology of hepatosteatosis and hepatic insulin resistance. Lipids constitute…”
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Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity by Rozman-Pungercar, J, Kopitar-Jerala, N, Bogyo, M, Turk, D, Vasiljeva, O, Stefe, I, Vandenabeele, P, Brömme, D, Puizdar, V, Fonović, M, Trstenjak-Prebanda, M, Dolenc, I, Turk, V, Turk, B

“…We report here that a number of commonly used small peptide caspase inhibitors consisting of a caspase recognition sequence linked to chloromethylketone,…”
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Effects of diet-matrix on volatile organic compounds in breath in diet-induced obese mice by Kistler, M, Szymczak, W, Fedrigo, M, Fiamoncini, J, Höllriegl, V, Hoeschen, C, Klingenspor, M, Hrabě de Angelis, M, Rozman, J

“…Breath gas analysis in humans proved successful in identifying disease states and assessing metabolic functions in a non-invasive way. While many studies…”
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Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo by Bolze, F, Rink, N, Brumm, H, Kühn, R, Mocek, S, Schwarz, A-E, Kless, C, Biebermann, H, Wurst, W, Rozman, J, Klingenspor, M

“…Several genetic diseases are triggered by nonsense mutations leading to the formation of truncated and defective proteins. Aminoglycosides have the capability…”
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Generation of Mice Lacking DUF1220 Protein Domains: Effects on Fecundity and Hyperactivity by Keeney, J. G., O’Bleness, M. S., Anderson, N., Davis, J. M., Arevalo, N., Busquet, N., Chick, W., Rozman, J., Hölter, S. M., Garrett, L., Horsch, M., Beckers, J., Wurst, W., Klingenspor, M., Restrepo, D., de Angelis, M. Hrabě, Sikela, J. M.

“…Sequences encoding DUF1220 protein domains show the most extreme human lineage-specific copy number increase of any coding region in the genome and have been…”
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Postural stability of Parkinson's disease patients is improved by decreasing rigidity by Bartolić, A., Pirtošek, Z., Rozman, J., Ribarič, S.

“…Postural instability has a big impact on the quality of life of patients with Parkinson's disease (PD) as it often leads to an insecure stance and fall. We…”
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PC1/3 and PC2 Gene Expression and Post-Translational Endoproteolytic Pro-Opiomelanocortin Processing is Regulated by Photoperiod in the Seasonal Siberian Hamster (Phodopus sungorus) by Helwig, M., Khorooshi, R. M. H., Tups, A., Barrett, P., Archer, Z. A., Exner, C., Rozman, J., Braulke, L. J., Mercer, J. G., Klingenspor, M.

“…A remarkable feature of the seasonal adaptation displayed by the Siberian hamster (Phodopus sungorus) is the ability to decrease food intake and body weight…”
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Modulation of visceral function by selective stimulation of the left vagus nerve in dogs by Rozman, J., Bunc, M.

“…The superficial regions of the left vagus nerves of a dog were selectively stimulated with 39-electrode spiral cuffs having 13 circumferential groups of three…”
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Progeny Analysis of Glyphosate Selected Transgenic Soybeans Derived from Agrobacterium‐Mediated Transformation by Clemente, Thomas E., LaVallee, Bradley J., Howe, Arlene R., Conner‐Ward, Dannette, Rozman, Renee J., Hunter, Priscilla E., Broyles, Debra L., Kasten, Daniel S., Hinchee, Maud A.

“…Glyphosate selection has been implemented into an Agrobacterium‐mediated transformation system for soybean [Glycine max (L.) Merr.]. Cotyledonary explants were…”
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Influence of Sheet Metal on Fine-Blanking Process by Česnik, D., Rozman, J., Bizjak, M.

“…A force that acts on the punch during fine-blanking of parts to be used in turbochargers for automotive diesel engines was measured. The aim of the research…”
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Seasonal changes of myostatin expression and its relation to body Mass acclimation in the Djungarian hamster, Phodopus sungorus by Braulke, L.J., Heldmaier, G., Berriel Diaz, M., Rozman, J., Exner, C.

“…The Djungarian hamster is an animal that is prominent for distinct seasonal adaptations. Cued by shortening day length in autumn they spontaneously exhibit…”
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Mixed cultures of allogeneic dendritic cells are phenotypically and functionally stable – a potential for primary cell-based “off the shelf” product generation by Švajger, Urban, J. Rožman, Primož

“…Vaccination against tumors using antigen-pulsed dendritic cell (DC) vaccines has greatly evolved over the last decade, with hundreds of active human clinical…”
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Synergistic Effects of Interferon-γ and Vitamin D3 Signaling in Induction of ILT-3highPDL-1high Tolerogenic Dendritic Cells by Švajger, Urban, Rožman, Primož J.

“…In the past, interferon (IFN)-γ and vitamin D 3 (vit D 3 ) have both been associated with induction of tolerogenic characteristics in human dendritic cells…”
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