Search Results - "Rozlan, Sandra"
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Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing
Published in Nature communications (30-06-2022)“…Universal CAR T-cell therapies are poised to revolutionize cancer treatment and to improve patient outcomes. However, realizing these advantages in an…”
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Altered thymic function during interferon therapy in HCV-infected patients
Published in PloS one (16-04-2012)“…Interferon alpha (IFNα) therapy, despite good efficacy in curing HCV infection, leads to major side effects, in particular inducement of a strong peripheral…”
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HIV reservoir dynamics in HAART-treated poor immunological responder patients under IL-7 therapy
Published in AIDS (London) (27-03-2018)“…OBJECTIVES:Recombinant Human IL-7 (rhIL-7) therapy allows reconstituting systemic and tissue-associated CD4 T-cell populations in HIV-infected poor…”
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Multi-armored allogeneic MUC1 CAR T cells enhance efficacy and safety in triple-negative breast cancer
Published in Science advances (30-08-2024)“…Solid tumors, such as triple-negative breast cancer (TNBC), are biologically complex due to cellular heterogeneity, lack of tumor-specific antigens, and an…”
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Modified interferon-α subtypes production and chemokine networks in the thymus during acute simian immunodeficiency virus infection, impact on thymopoiesis
Published in AIDS (London) (15-05-2014)“…Thymus dysfunction characterizes human/simian immunodeficiency virus (SIV) infections and contributes to physiopathology. However, both the mechanisms involved…”
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Injection of glycosylated recombinant simian IL-7 provokes rapid and massive T-cell homing in rhesus macaques
Published in Blood (23-07-2009)“…Interleukin-7 (IL-7), the principal cytokine implicated in thymopoiesis and peripheral T-cell homeostasis, is presently under evaluation in human diseases…”
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CD4+ recent thymic emigrants are infected by HIV in vivo, implication for pathogenesis
Published in AIDS (London) (01-06-2011)“…The contribution of naive CD4⁺ T cells to the pool of HIV-infected cells remains poorly described. This study aimed at evaluating HIV infection in naive T-cell…”
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Interleukin-7 treatment counteracts IFN-α therapy-induced lymphopenia and stimulates SIV-specific cytotoxic T lymphocyte responses in SIV-infected rhesus macaques
Published in Blood (16-12-2010)“…Interferon-α (IFN-α)–based therapy is presently the standard treatment for hepatitis C virus (HCV)–infected patients. Despite good effectiveness, this cytokine…”
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Initiation of c-ART in HIV-1 Infected Patients Is Associated With a Decrease of the Metabolic Activity of the Thymus Evaluated Using FDG-PET/Computed Tomography
Published in Journal of acquired immune deficiency syndromes (1999) (01-09-2012)“…BACKGROUND:The role of the thymus in the depletion or restoration of T-cell pool in HIV infection is still debatable. Studies are hampered by the lack of…”
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PS1-034. Accelerated thymocyte maturation during the acute phase of SIV infection in rhesus macaques
Published in Cytokine (Philadelphia, Pa.) (01-10-2011)Get full text
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PS1-107 Different interferon alpha subtypes are sequentially produced in organs during acute SIV infection in rhesus macaques
Published in Cytokine (Philadelphia, Pa.) (01-10-2011)Get full text
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