Search Results - "Rozhin, Jurij"

Pericellular pH affects distribution and secretion of cathepsin B in malignant cells by ROZHIN, J, SAMENI, M, ZIEGLER, G, SLOANE, B. F

“…Redistribution of lysosomes to the cell surface and secretion of lysosomal proteases appear to be general phenomena in cells that participate in local…”
Get full text

Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples by Emmert-Buck, MR, Roth, MJ, Zhuang, Z, Campo, E, Rozhin, J, Sloane, BF, Liotta, LA, Stetler-Stevenson, WG

“…Gelatinase A (MMP-2) and cathepsin B are proteinases which have been proposed to participate in human tumor invasion and metastasis. Precise quantitation of…”
Get full text

Cathepsin B expression and localization in glioma progression and invasion by REMPEL, S. A, ROSENBLUM, M. L, MIKKELSEN, T, PEI-SHA YAN, ELLIS, K. D, GOLEMBIESKI, W. A, SAMENI, M, ROZHIN, J, ZIEGLER, G, SLOANE, B. F

“…The poor prognosis of human malignant gliomas is due to their invasion and recurrence, the molecular mechanisms of which remain poorly characterized. We have…”
Get full text

Membrane association of cathepsin B can be induced by transfection of human breast epithelial cells with c-Ha-ras oncogene by SLOANE, B. F, MOIN, K, SAMENI, M, TAIT, L. R, ORZHIN, J, ZIEGLER, G

“…Alterations in trafficking and increases in expression of the lysosomal proteases cathepsins B, D and L have been observed in transformed cells and malignant…”
Get full text

Plasma membrane association of cathepsin B in human prostate cancer: Biochemical and immunogold electron microscopic analysis by Sinha, Akhouri A., Jamuar, Mahendra P., Wilson, Michael J., Rozhin, Jurij, Sloane, Bonnie F.

“…Background Cathepsin B (CB), a cysteine protease, is usually found in perinuclear lysosomes of epithelial cells of normal organs and non‐malignant tumors, but…”
Get full text

Specificity Studies on Bovine Adrenal Estrogen Sulfotransferase by Rozhin, J, Soderstrom, R L, Brooks, S C

“…The substrate requirements for estrogen sulfotransferase have been examined. Structural changes in all four rings of the estratriene nucleus affected…”
Get full text

Cathepsin B and its endogenous inhibitors: the role in tumor malignancy by SLOANE, B. F, MOIN, K, KREPELA, E, ROZHIN, J

“…Several lysosomal proteinases including the cysteine proteinase cathepsin B have been implicated in malignant progression of tumors. Many investigators have…”
Get full text

A lipoxygenase metabolite, 12-(S)-HETE, stimulates protein kinase C-mediated release of cathepsin B from malignant cells by Honn, K V, Timár, J, Rozhin, J, Bazaz, R, Sameni, M, Ziegler, G, Sloane, B F

“…The process of tumor cell invasion of the basement membrane is proposed to consist of three steps: attachment, local proteolysis and migration. 12-(S)-HETE, a…”
Get more information

Cathepsin B: Association with Plasma Membrane in Metastatic Tumors by Sloane, Bonnie F., Rozhin, Jurij, Johnson, Karen, Taylor, Heide, Crissman, John D., Honn, Kenneth V.

“…The subcellular localization of cathepsin B activity (EC 3.4.22.1) in three murine melanomas of increasing metastatic potential (Cloudman < B16-F1 < B16…”
Get full text

Membrane-associated cathepsin L: a role in metastasis of melanomas by Rozhin, J, Wade, R L, Honn, K V, Sloane, B F

“…Subcellular distribution of cathepsin L, the major protein released by transformed or ras transfected fibroblasts, was examined in murine liver, murine B16…”
Get more information

Cathepsin B to cysteine proteinase inhibitor balance in metastatic cell subpopulations isolated from murine tumors by Rozhin, J, Gomez, A P, Ziegler, G H, Nelson, K K, Chang, Y S, Fong, D, Onoda, J M, Honn, K V, Sloane, B F

“…Our laboratories have previously demonstrated that the malignancy of human and animal tumors is associated with increases in cathepsin B activity, due in part…”
Get full text

Ornithine decarboxylase activity in the rat and human colon by ROZHIN, J, WILSON, P. S, BULL, A. W, NIGRO, N. D

“…We have investigated the effect of age, a high-fat diet, sodium deoxycholate, and the ornithine analogue alpha-difluoromethylornithine on ornithine…”
Get full text

Properties of a plasma membrane-associated cathepsin B-like cysteine proteinase in metastatic B16 melanoma variants by ROZHIN, J, ROBINSON, D, STEVENS, M. A, LAH, T. T, HONN, K. V, RYAN, R. E, SLOANE, B. F

“…Activities of a cathepsin B-like cysteine proteinase have previously been observed to correlate with the malignancy of several animal and human tumors. Plasma…”
Get full text

Enhanced levels of cathepsin B mRNA in murine tumors by Moin, Kamiar, Rozhin, Jurij, McKernan, Timothy B., Sanders, Virginia J., Fong, Dunne, Honn, Kenneth V., Sloane, Bonnie F.

“…Relative amounts of mRNA for cathepsin B were measured in normal murine liver and three murine tumors, an invasive liver tumor (hepatoma, Hepa cl 9) and two…”
Get full text

STUDIES ON THE GROWTH PATTERN AND KINETICS OF INDUCED BETA-GALACTOSIDASE SYNTHESIS IN SYNCHRONIZED CULTURES OF E. COLI by ROZHIN, JURIJ

Get full text

Cysteine endopeptidases and their inhibitors in malignant progression of rat embryo fibroblasts by Sloane, B F, Rozhin, J, Moin, K, Ziegler, G, Fong, D, Muschel, R J

“…Cathepsins B and L and their endogenous inhibitors were evaluated in rat embryo fibroblast lines which have been developed as a model system for the study of…”
Get more information

The Hexosamine Content of the Serum Globulins in Normal and Pathological Sera 1 by Bollet, Alfred Jay, Rozhin, Jurij, Simpson, William

Get full text

Some adenine and adenosine methylene-bridged estrogens by Iyer, Vaidyanathan K, Butler, W. Barkley, Horwitz, Jerome P, Rozhin, Jurij, Brooks, Sam C, Corombos, Jeanne, Kessel, David

Get full text

Enzyme assay in cultures of Escherichia coli by a continuous flow method based on lysis from without by a phage ghost by Ou, C T, Matsumoto, I, Rozhin, J, Tchen, T T

Get more information