Search Results - "Rozenberg, D."

A Phase 1, Placebo-controlled, Randomized, Single Ascending Dose Study and a Volunteer Infection Study to Characterize the Safety, Pharmacokinetics, and Antimalarial Activity of the Plasmodium Phosphatidylinositol 4-Kinase Inhibitor MMV390048 by McCarthy, James S, Donini, Cristina, Chalon, Stephan, Woodford, John, Marquart, Louise, Collins, Katharine A, Rozenberg, Felix D, Fidock, David A, Cherkaoui-Rbati, Mohammed H, Gobeau, Nathalie, Möhrle, Jörg J

“…Abstract Background MMV390048 is the first Plasmodium phosphatidylinositol 4-kinase inhibitor to reach clinical development as a new antimalarial. We aimed to…”
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Short Physical Performance Battery Scores at Lung Transplant Assessment: Relationship to Early Transplant Outcomes and Response to Pre-Habilitation by Wickerson, L., Rozenberg, D., Helm, D., Gottesman, C., Mathur, S., Singer, L.G.

“…The short physical performance battery (SPPB) has been used as a measure of phenotypic frailty in adult lung transplant candidates. It is associated with an…”
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Clinical Implications of Sarcopenia in Patients Undergoing Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertention by Balki, I., Perrot, M.D., Zaeimi, F., Granton, J.T., Thenganatt, J., McInnis, M., Donahoe, L., Rozenberg, D.

“…Pulmonary endarterectomy (PEA) is a curative surgical option for patients with chronic thromboembolic pulmonary hypertension (CTEPH), a disease resulting from…”
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Meeting Report: Consensus Recommendations for a Research Agenda in Exercise in Solid Organ Transplantation by Mathur, S., Janaudis‐Ferreira, T., Wickerson, L., Singer, L. G., Patcai, J., Rozenberg, D., Blydt‐Hansen, T., Hartmann, E. L., Haykowsky, M., Helm, D., High, K., Howes, N., Kamath, B. M., Lands, L., Marzolini, S., Sonnenday, C.

“…With improved survival rates in solid organ transplantation there has been an increased focus on long‐term outcomes following transplant, including physical…”
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Association of Thoracic Muscle Cross-Sectional Area and Clinical Outcomes in Lung Transplant Candidates by Rozenberg, D, Singer, L.G, Mendes, P, Mathur, S

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Frailty and Clinical Benefits with Lung Transplantation by Rozenberg, D, Mathur, S, Wickerson, L, Chowdhury, N.A, Singer, L.G

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Evaluation of Sarcopenia in Lung Transplant Candidates by Rozenberg, D, Mathur, S, Wickerson, L, Chowdhury, N.A, Singer, L.G

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Agreement between Fried Frailty Phenotype and Cumulative Deficits Frailty Indices: A Prospective Multi-Center Study by Rozenberg, D., Singer, L.G., Neely, M.L., Weber, J.M., Kopetskie, H.A., Sever, M.L., Kirchner, J., Frankel, C.W., Todd, J.L., Williams, N., Robien, M.A., Belperio, J., Budev, M.M., Tsuang, W., Reynolds, J.M., Turner, D., Shah, P.D., Palmer, S.M., Snyder, L.D.

“…Frailty is gaining increased recognition in the evaluation of lung transplant (LTx) candidates. The Fried Frailty Phenotype (FFP) index has been the most…”
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Frailty in the Lung Transplant Candidate by Rozenberg, D, Wickerson, L, Mathur, S, Keshavjee, S, Singer, L.G

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S1338 Mapping Culturable Microbes of Perianal Fistula in Patients With Crohn’s Disease by Rozenberg, Felix D., Pan, Samuel, Lacoste, Joshua, Giselbrecht, Elisabeth, Wong, Serre-yu

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Carbapenemase-producing Enterobacterales causing secondary infections during the COVID-19 crisis at a New York City hospital by Gomez-Simmonds, Angela, Annavajhala, Medini K, McConville, Thomas H, Dietz, Donald E, Shoucri, Sherif M, Laracy, Justin C, Rozenberg, Felix D, Nelson, Brian, Greendyke, William G, Furuya, E Yoko, Whittier, Susan, Uhlemann, Anne-Catrin

“…Abstract Background Patients with COVID-19 may be at increased risk for secondary bacterial infections with MDR pathogens, including carbapenemase-producing…”
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Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study by Llanos-Cuentas, Alejandro, Casapia, Martin, Chuquiyauri, Raúl, Hinojosa, Juan-Carlos, Kerr, Nicola, Rosario, Maria, Toovey, Stephen, Arch, Robert H, Phillips, Margaret A, Rozenberg, Felix D, Bath, Jade, Ng, Caroline L, Cowell, Annie N, Winzeler, Elizabeth A, Fidock, David A, Baker, Mark, Möhrle, Jörg J, Hooft van Huijsduijnen, Rob, Gobeau, Nathalie, Araeipour, Nada, Andenmatten, Nicole, Rückle, Thomas, Duparc, Stephan

“…DSM265 is a novel, long-duration inhibitor of plasmodium dihydroorotate dehydrogenase (DHODH) with excellent selectivity over human DHODH and activity against…”
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S1252 Associations Between Social Determinants of Health on Psychosocial Well-Being and Quality of Life in a Diverse Cohort of Individuals With Perianal Fistulizing Crohn’s Disease by Shenoy, Shabari, DeBroff, Jake, Lacoste, Joshua, Giselbrecht, Elisabeth, Gbenebitse, Nicole O, Rozenberg, Felix D., Keefer, Laurie, Wong, Serre-yu

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Population structure of blaKPC-harbouring IncN plasmids at a New York City medical centre and evidence for multi-species horizontal transmission by Gomez-Simmonds, Angela, Annavajhala, Medini K, Tang, Nina, Rozenberg, Felix D, Ahmad, Mehrose, Park, Heekuk, Lopatkin, Allison J, Uhlemann, Anne Catrin

“…Abstract Background Carbapenem-resistant Enterobacterales (CRE) are highly concerning MDR pathogens. Horizontal transfer of broad-host-range IncN plasmids may…”
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CrrB Positively Regulates High-Level Polymyxin Resistance and Virulence in Klebsiella pneumoniae by McConville, Thomas H., Annavajhala, Medini K., Giddins, Marla J., Macesic, Nenad, Herrera, Carmen M., Rozenberg, Felix D., Bhushan, Gitanjali L., Ahn, Danielle, Mancia, Filippo, Trent, M. Stephen, Uhlemann, Anne-Catrin

“…Polymyxin resistance (PR) threatens the treatment of carbapenem-resistant Klebsiella pneumoniae (CRKP) infections. PR frequently arises through chemical…”
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Evolution of the environmental microbiota of a new neonatal intensive care unit (NICU) and implications for infection prevention and control by Zachariah, Philip, Rozenberg, Felix D, Stump, Stephania, Moscoso, Dagmara I, Krishnamurthy, Ganga, Saiman, Lisa, Uhlemann, Anne-Catrin, Freedberg, Daniel E

“…To describe changes in the environmental microbiota of a new neonatal intensive care unit (NICU) and potential implications for infection prevention and…”
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The gut microbiome, short chain fatty acids, and related metabolites in cystic fibrosis patients with and without colonic adenomas by Baldwin-Hunter, Brittany L, Rozenberg, Felix D, Annavajhala, Medini K, Park, Heekuk, DiMango, Emily A, Keating, Claire L, Uhlemann, Anne-Catrin, Abrams, Julian A

“…Adults with cystic fibrosis (CF) are at increased risk for colon cancer. CF patients have reductions in intestinal bacteria that produce short chain fatty…”
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Pathomorphology and pathogenic role of myocardial bridges in sudden cardiac death by Rozenberg, V D, Nepomnyashchikh, L M

“…Pathognomonic incidence of myocardial bridges during obstructive hypertrophic cardiomyopathy, hypertension, and ischemic heart disease was established…”
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(99) - Comparison of Frailty Trajectories in Lung Transplantation by Rajkumar, A., Chowdhury, N., Rozenberg, D., Riddell, P., Rockwood, K., Mathur, S., Singer, L.G.

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Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness by Mok, Sachel, Yeo, Tomas, Hong, Davin, Shears, Melanie J, Ross, Leila S, Ward, Kurt E, Dhingra, Satish K, Kanai, Mariko, Bridgford, Jessica L, Tripathi, Abhai K, Mlambo, Godfree, Burkhard, Anna Y, Ansbro, Megan R, Fairhurst, Kate J, Gil-Iturbe, Eva, Park, Heekuk, Rozenberg, Felix D, Kim, Jonathan, Mancia, Filippo, Fairhurst, Rick M, Quick, Matthias, Uhlemann, Anne-Catrin, Sinnis, Photini, Fidock, David A

“…Drug-resistant parasites have swept across Southeast Asia and now threaten Africa. By implementing a genetic cross using humanized mice, we report the…”
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