Search Results - "Rozemuller, Annemieke Jm"

Neuroinflammation in Alzheimer's disease wanes with age by Hoozemans, Jeroen J M, Rozemuller, Annemieke J M, van Haastert, Elise S, Eikelenboom, Piet, van Gool, Willem A

“…Inflammation is a prominent feature in Alzheimer's disease (AD). It has been proposed that aging has an effect on the function of inflammation in the brain,…”
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Cerebral amyloid angiopathy severity is linked to dilation of juxtacortical perivascular spaces by van Veluw, Susanne J, Biessels, Geert Jan, Bouvy, Willem H, Spliet, Wim GM, Zwanenburg, Jaco JM, Luijten, Peter R, Macklin, Eric A, Rozemuller, Annemieke JM, Gurol, M Edip, Greenberg, Steven M, Viswanathan, Anand, Martinez-Ramirez, Sergi

“…Perivascular spaces are an emerging marker of small vessel disease. Perivascular spaces in the centrum semiovale have been associated with cerebral amyloid…”
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Whether, when and how chronic inflammation increases the risk of developing late-onset Alzheimer's disease by Eikelenboom, Piet, Hoozemans, Jeroen Jm, Veerhuis, Rob, van Exel, Eric, Rozemuller, Annemieke Jm, van Gool, Willem A

“…Neuropathological studies have revealed the presence of a broad variety of inflammation-related proteins (complement factors, acute-phase proteins,…”
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Presymptomatic and early pathological features of MAPT-associated frontotemporal lobar degeneration by Giannini, Lucia Aa, Mol, Merel O, Rajicic, Ana, van Buuren, Renee, Sarkar, Lana, Arezoumandan, Sanaz, Ohm, Daniel T, Irwin, David J, Rozemuller, Annemieke Jm, van Swieten, John C, Seelaar, Harro

“…Early pathological features of frontotemporal lobar degeneration (FTLD) due to MAPT pathogenic variants (FTLD-MAPT) are understudied, since early-stage tissue…”
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Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease by Hoozemans, Jeroen J M, van Haastert, Elise S, Veerhuis, Robert, Arendt, Thomas, Scheper, Wiep, Eikelenboom, Piet, Rozemuller, Annemieke J M

“…Neuronal expression of cyclooxygenase-2 (COX-2) and cell cycle proteins is suggested to contribute to neurodegeneration during Alzheimer's disease (AD). The…”
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NG2 cells, a new trail for Alzheimer's disease mechanisms? by Nielsen, Henrietta M, Ek, Danyal, Avdic, Una, Orbjörn, Camilla, Hansson, Oskar, Veerhuis, Robert, Rozemuller, Annemieke Jm, Brun, Arne, Minthon, Lennart, Wennström, Malin

“…Neuron Glial 2 (NG2) cells are glial cells known to serve as oligodendrocyte progenitors as well as modulators of the neuronal network. Altered NG2 cell…”
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Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease? by de Vries, Helga E., Witte, Maarten, Hondius, David, Rozemuller, Annemieke J.M., Drukarch, Benjamin, Hoozemans, Jeroen, van Horssen, Jack

“…Neurodegenerative diseases share various pathological features, such as accumulation of aberrant protein aggregates, microglial activation, and mitochondrial…”
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Heterogeneous histopathology of cortical microbleeds in cerebral amyloid angiopathy by van Veluw, Susanne J, Biessels, Geert Jan, Klijn, Catharina J.M, Rozemuller, Annemieke J.M

“…OBJECTIVE:To investigate the histopathologic substrate of microbleeds detected on 7T postmortem MRI in autopsy cases with severe cerebral amyloid angiopathy…”
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Stage-dependent nigral neuronal loss in incidental Lewy body and Parkinson's disease by Dijkstra, Anke A., Voorn, Pieter, Berendse, Henk W., Groenewegen, Henk J., Rozemuller, Annemieke J.M., van de Berg, Wilma D.J.

“…To gain a better understanding of the significance of α‐synuclein pathological conditions during disease progression in Parkinson's disease, we investigated…”
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The unfolded protein response is associated with early tau pathology in the hippocampus of tauopathies by Nijholt, Diana AT, van Haastert, Elise S, Rozemuller, Annemieke JM, Scheper, Wiep, Hoozemans, Jeroen JM

“…The unfolded protein response (UPR) is a stress response activated upon disturbed homeostasis in the endoplasmic reticulum (ER). Previously, we reported that…”
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Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update by Mackenzie, Ian R. A., Neumann, Manuela, Bigio, Eileen H., Cairns, Nigel J., Alafuzoff, Irina, Kril, Jillian, Kovacs, Gabor G., Ghetti, Bernardino, Halliday, Glenda, Holm, Ida E., Ince, Paul G., Kamphorst, Wouter, Revesz, Tamas, Rozemuller, Annemieke J. M., Kumar-Singh, Samir, Akiyama, Haruhiko, Baborie, Atik, Spina, Salvatore, Dickson, Dennis W., Trojanowski, John Q., Mann, David M. A.

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Nigral Pathology Contributes to Microstructural Integrity of Striatal and Frontal Tracts in Parkinson's Disease by Lin, Chen-Pei, Knoop, Lydian E J, Frigerio, Irene, Bol, John G J M, Rozemuller, Annemieke J M, Berendse, Henk W, Pouwels, Petra J W, van de Berg, Wilma D J, Jonkman, Laura E

“…Motor and cognitive impairment in Parkinson's disease (PD) is associated with dopaminergic dysfunction that stems from substantia nigra (SN) degeneration and…”
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Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations by Mackenzie, Ian R. A., Neumann, Manuela, Bigio, Eileen H., Cairns, Nigel J., Alafuzoff, Irina, Kril, Jillian, Kovacs, Gabor G., Ghetti, Bernardino, Halliday, Glenda, Holm, Ida E., Ince, Paul G., Kamphorst, Wouter, Revesz, Tamas, Rozemuller, Annemieke J. M., Kumar-Singh, Samir, Akiyama, Haruhiko, Baborie, Atik, Spina, Salvatore, Dickson, Dennis W., Trojanowski, John Q., Mann, David M. A.

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The Spectrum of MR Detectable Cortical Microinfarcts: A Classification Study with 7-Tesla Postmortem MRI and Histopathology by van Veluw, Susanne J, Zwanenburg, Jaco JM, Rozemuller, Annemieke JM, Luijten, Peter R, Spliet, Wim GM, Biessels, Geert Jan

“…Cerebral microinfarcts (CMIs) are common neuropathologic findings in aging and dementia. We explored the spectrum of cortical CMIs that can be visualized with…”
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Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy by van Veluw, Susanne J., Kuijf, Hugo J., Charidimou, Andreas, Viswanathan, Anand, Biessels, Geert Jan, Rozemuller, Annemieke J. M., Frosch, Matthew P., Greenberg, Steven M.

“…Microhemorrhages are strongly associated with advanced cerebral amyloid angiopathy (CAA). Although it has been frequently proposed that the deposition of Aβ in…”
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The Neuropathology of Gluten-Related Neurological Disorders: A Systematic Review by Rouvroye, Maxine D, Zis, Panagiotis, Van Dam, Anne-Marie, Rozemuller, Annemieke J M, Bouma, Gerd, Hadjivassiliou, Marios

“…Gluten-related neurological disorders (GRND) represent a spectrum of neurological manifestations that are triggered by gluten. In coeliac disease, a T-cell…”
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Prion protein amyloidosis with divergent phenotype associated with two novel nonsense mutations in PRNP by Jansen, Casper, Parchi, Piero, Capellari, Sabina, Vermeij, Ad J., Corrado, Patrizia, Baas, Frank, Strammiello, Rosaria, van Gool, Willem A., van Swieten, John C., Rozemuller, Annemieke J. M.

“…Stop codon mutations in the gene encoding the prion protein ( PRNP ) are very rare and have thus far only been described in two patients with prion protein…”
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Frequency of ubiquitin and FUS-positive, TDP-43-negative frontotemporal lobar degeneration by Seelaar, Harro, Klijnsma, Kirsten Y., de Koning, Inge, van der Lugt, Aad, Chiu, Wang Zheng, Azmani, Asma, Rozemuller, Annemieke J. M., van Swieten, John C.

“…Frontotemporal lobar degeneration (FTLD) is a clinically, genetically and pathologically heterogeneous disorder. Within FTLD with ubiquitin-positive inclusions…”
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Three VCP Mutations in Patients with Frontotemporal Dementia by Wong, Tsz Hang, Pottier, Cyril, Hondius, David C, Meeter, Lieke H H, van Rooij, Jeroen G J, Melhem, Shami, van Minkelen, Rick, van Duijn, Cornelia M, Rozemuller, Annemieke J M, Seelaar, Harro, Rademakers, Rosa, van Swieten, John C

“…Valosin-containing protein (VCP) is involved in multiple cellular activities. Mutations in VCP lead to heterogeneous clinical presentations including inclusion…”
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Dickkopf-related protein 3 is a potential A[beta]-associated protein in Alzheimer's Disease by Bruggink, Kim A, Kuiperij, H Bea, Gloerich, Jolein, Otte-Holler, Irene, Rozemuller, Annemieke JM, Claassen, Jurgen AHR, Kusters, Benno, Verbeek, Marcel M

“…Amyloid-[beta] (A[beta]) is the most prominent protein in Alzheimer's disease (AD) senile plaques. In addition, A[beta] interacts with a variety of…”
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