Search Results - "Rozek, Laura S."

Understanding Vaccine Hesitancy in the Context of COVID-19: The Role of Trust and Confidence in a Seventeen-Country Survey by Rozek, Laura S., Jones, Pauline, Menon, Anil, Hicken, Allen, Apsley, Samantha, King, Elizabeth J.

“…Objectives: An effective vaccine to SARS-CoV-2 cannot be successfully deployed if a significant number of people worldwide are unwilling to accept it. We…”
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MethylSig: a whole genome DNA methylation analysis pipeline by Park, Yongseok, Figueroa, Maria E, Rozek, Laura S, Sartor, Maureen A

“…DNA methylation plays critical roles in gene regulation and cellular specification without altering DNA sequences. The wide application of reduced…”
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Tumor-Infiltrating Lymphocytes, Crohn's-Like Lymphoid Reaction, and Survival From Colorectal Cancer by Rozek, Laura S, Schmit, Stephanie L, Greenson, Joel K, Tomsho, Lynn P, Rennert, Hedy S, Rennert, Gad, Gruber, Stephen B

“…While clinical outcomes from colorectal cancer (CRC) are influenced by stage at diagnosis and treatment, mounting evidence suggests that an enhanced…”
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Alzheimer's disease and environmental exposure to lead: the epidemiologic evidence and potential role of epigenetics by Bakulski, Kelly M, Rozek, Laura S, Dolinoy, Dana C, Paulson, Henry L, Hu, Howard

“…Several lines of evidence indicate that the etiology of late-onset Alzheimer's disease (LOAD) is complex, with significant contributions from both genes and…”
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Global adoption of personal and social mitigation behaviors during COVID-19: The role of trust & confidence by Jones, Pauline, Menon, Anil, Hicken, Allen, Rozek, Laura S

“…What influences the adoption of SARS-CoV-2 mitigation behaviors-both personal, such as mask wearing and frequent handwashing, and social, such as avoiding…”
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PePr: a peak-calling prioritization pipeline to identify consistent or differential peaks from replicated ChIP-Seq data by Zhang, Yanxiao, Lin, Yu-Hsuan, Johnson, Timothy D, Rozek, Laura S, Sartor, Maureen A

“…ChIP-Seq is the standard method to identify genome-wide DNA-binding sites for transcription factors (TFs) and histone modifications. There is a growing need to…”
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Descriptive Epidemiology of breast and gynecological cancers among patients attending Saint Paul's Hospital Millennium Medical College, Ethiopia by Hailu, Haimanot E, Mondul, Alison M, Rozek, Laura S, Geleta, Temesgen

“…Cancer is a leading cause of death in both more and less economically developed countries; the burden is expected to grow in less developed countries, such as…”
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Epigenetics: relevance and implications for public health by Rozek, Laura S, Dolinoy, Dana C, Sartor, Maureen A, Omenn, Gilbert S

“…Improved understanding of the multilayer regulation of the human genome has led to a greater appreciation of environmental, nutritional, and epigenetic risk…”
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Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex by Bakulski, Kelly M, Dolinoy, Dana C, Sartor, Maureen A, Paulson, Henry L, Konen, John R, Lieberman, Andrew P, Albin, Roger L, Hu, Howard, Rozek, Laura S

“…Evidence supports a role for epigenetic mechanisms in the pathogenesis of late-onset Alzheimer's disease (LOAD), but little has been done on a genome-wide…”
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Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional Profiling by Colacino, Justin A., Azizi, Ebrahim, Brooks, Michael D., Harouaka, Ramdane, Fouladdel, Shamileh, McDermott, Sean P., Lee, Michael, Hill, David, Madden, Julie, Boerner, Julie, Cote, Michele L., Sartor, Maureen A., Rozek, Laura S., Wicha, Max S.

“…During development, the mammary gland undergoes extensive remodeling driven by stem cells. Breast cancers are also hierarchically organized and driven by…”
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Dietary antioxidant and anti-inflammatory intake modifies the effect of cadmium exposure on markers of systemic inflammation and oxidative stress by Colacino, Justin A., Arthur, Anna E., Ferguson, Kelly K., Rozek, Laura S.

“…Chronic cadmium exposure may cause disease through induction of systemic oxidative stress and inflammation. Factors that mitigate cadmium toxicity and could…”
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LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types by Kim, Jung H, Karnovsky, Alla, Mahavisno, Vasudeva, Weymouth, Terry, Pande, Manjusha, Dolinoy, Dana C, Rozek, Laura S, Sartor, Maureen A

“…The relative contribution of epigenetic mechanisms to carcinogenesis is not well understood, including the extent to which epigenetic dysregulation and somatic…”
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Breast Cancer Incidence Trends and Projections in Northeastern Thailand by Virani, Shama, Chindaprasirt, Jarin, Wirasorn, Kosin, Sookprasert, Aumkhae, Somintara, Ongart, Vachirodom, Damnern, Koonmee, Supinda, Srinakarin, Jirapon, Kamsa-Ard, Supot, Suwanrungruang, Krittika, Rozek, Laura S, Sriplung, Hutcha, Wiangnon, Surapon

“…The northeast has the lowest incidence of breast cancer of all regions in Thailand, although national rates are increasing. The heterogeneity in subnational…”
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A prospective study of LINE-1DNA methylation and development of adiposity in school-age children by Perng, Wei, Mora-Plazas, Mercedes, Marín, Constanza, Rozek, Laura S, Baylin, Ana, Villamor, Eduardo

“…Repetitive element DNA methylation is related to prominent obesity-related chronic diseases including cancer and cardiovascular disease; yet, little is known…”
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Genome-wide methylation and expression differences in HPV(+) and HPV(-) squamous cell carcinoma cell lines are consistent with divergent mechanisms of carcinogenesis by Sartor, Maureen A., Dolinoy, Dana C., Jones, Tamara R., Colacino, Justin A., Prince, Mark E.P., Carey, Thomas E., Rozek, Laura S.

“…Oncogenic human papillomaviruses (HPV) are associated with nearly all cervical cancers and are increasingly important in the etiology of oropharyngeal tumors…”
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Escalating burden of breast cancer in southern Thailand: Analysis of 1990–2010 incidence and prediction of future trends by Virani, Shama, Sriplung, Hutcha, Rozek, Laura S, Meza, Rafael

“…Abstract Background Thailand is undergoing an epidemiologic transition, with decreasing incidence of infectious diseases and increasing rates of chronic…”
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Age distribution,polyps and rectal cancer in the Egyptian population-based cancer registry by Veruttipong, Darlene, Soliman, Amr S, Gilbert, Samuel F, Blachley, Taylor S, Hablas, Ahmed, Ramadan, Mohamed, Rozek, Laura S, Seifeldin, Ibrahim A

“…AIM：To describe the clinical and epidemiologic profiles of the disease and to compare the findings with those generated from the previous hospital-based…”
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Dietary Fiber, Whole Grains, and Head and Neck Cancer Prognosis: Findings from a Prospective Cohort Study by Maino Vieytes, Christian A, Mondul, Alison M, Li, Zonggui, Zarins, Katie R, Wolf, Gregory T, Rozek, Laura S, Arthur, Anna E

“…No studies, to date, have examined the relationship between dietary fiber and recurrence or survival after head and neck cancer diagnosis. The aim of this…”
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Differences in prostate tumor characteristics and survival among religious groups in Songkhla, Thailand by Alvarez, Christian S, Villamor, Eduardo, Meza, Rafael, Rozek, Laura S, Sriplung, Hutcha, Mondul, Alison M

“…The incidence and mortality from prostate cancer is expected to increase in the next decade in Thailand. Despite the perceived lower risk in this population…”
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The role of area‐level socioeconomic disadvantage in racial disparities in cancer incidence in metropolitan Detroit by Purrington, Kristen S., Hastert, Theresa A., Madhav, K. C., Nair, Mrudula, Snider, Natalie, Ruterbusch, Julie J., Schwartz, Ann G., Stoffel, Elena M., Peters, Edward S., Rozek, Laura S.

“…Background Neighborhood deprivation is associated with both race and cancer incidence, but there is a need to better understand the effect of structural…”
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