Search Results - "Royla, Nadine"

A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer by von Eyss, Björn, Jaenicke, Laura A., Kortlever, Roderik M., Royla, Nadine, Wiese, Katrin E., Letschert, Sebastian, McDuffus, Leigh-Anne, Sauer, Markus, Rosenwald, Andreas, Evan, Gerard I., Kempa, Stefan, Eilers, Martin

“…In several developmental lineages, an increase in MYC expression drives the transition from quiescent stem cells to transit-amplifying cells. We show that MYC…”
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Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations by Fritsche-Guenther, Raphaela, Zasada, Christin, Mastrobuoni, Guido, Royla, Nadine, Rainer, Roman, Roßner, Florian, Pietzke, Matthias, Klipp, Edda, Sers, Christine, Kempa, Stefan

“…Metabolic reprogramming is as a hallmark of cancer, and several studies have reported that BRAF and KRAS tumors may be accompanied by a deregulation of…”
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The answer's in the tail: MYC mRNA has a metabolic sensor that supports cancer chemoresistance by Royla, Nadine, Kempa, Stefan

“…Our recent study shows that the translation of MYC mRNA (mRNA) is controlled by its 3′ untranslated region (UTR) in a process that depends on the availability…”
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The MYC mRNA 3′‐UTR couples RNA polymerase II function to glutamine and ribonucleotide levels by Dejure, Francesca R, Royla, Nadine, Herold, Steffi, Kalb, Jacqueline, Walz, Susanne, Ade, Carsten P, Mastrobuoni, Guido, Vanselow, Jens T, Schlosser, Andreas, Wolf, Elmar, Kempa, Stefan, Eilers, Martin

“…Deregulated expression of MYC enhances glutamine utilization and renders cell survival dependent on glutamine, inducing “glutamine addiction”. Surprisingly,…”
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Sortase A mediated site-specific immobilization for identification of protein interactions in affinity purification-mass spectrometry experiments by Kuropka, Benno, Royla, Nadine, Freund, Christian, Krause, Eberhard

“…Proteomics approaches using MS in combination with affinity purification have emerged as powerful tools to study protein‐protein interactions. Here we make use…”
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Abrogating GPT2 in triple‐negative breast cancer inhibits tumor growth and promotes autophagy by Mitra, Devina, Vega‐Rubin‐de‐Celis, Silvia, Royla, Nadine, Bernhardt, Stephan, Wilhelm, Heike, Tarade, Nooraldeen, Poschet, Gernot, Buettner, Michael, Binenbaum, Ilona, Borgoni, Simone, Vetter, Martina, Kantelhardt, Eva Johanna, Thomssen, Christoph, Chatziioannou, Aristotelis, Hell, Rüdiger, Kempa, Stefan, Müller‐Decker, Karin, Wiemann, Stefan

“…Uncontrolled proliferation and altered metabolic reprogramming are hallmarks of cancer. Active glycolysis and glutaminolysis are characteristic features of…”
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