Search Results - "Royer, Guilhem"
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mcr-9 , an Inducible Gene Encoding an Acquired Phosphoethanolamine Transferase in Escherichia coli, and Its Origin
Published in Antimicrobial agents and chemotherapy (01-09-2019)“…The plasmid-located gene, encoding a putative phosphoethanolamine transferase, was identified in a colistin-resistant human fecal strain belonging to a very…”
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AI-based mobile application to fight antibiotic resistance
Published in Nature communications (19-02-2021)“…Antimicrobial resistance is a major global health threat and its development is promoted by antibiotic misuse. While disk diffusion antibiotic susceptibility…”
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Genome wide association study of Escherichia coli bloodstream infection isolates identifies genetic determinants for the portal of entry but not fatal outcome
Published in PLoS genetics (24-03-2022)“…Escherichia coli is an important cause of bloodstream infections (BSI), which is of concern given its high mortality and increasing worldwide prevalence…”
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Epistatic interactions between the high pathogenicity island and other iron uptake systems shape Escherichia coli extra-intestinal virulence
Published in Nature communications (20-06-2023)“…The intrinsic virulence of extra-intestinal pathogenic Escherichia coli is associated with numerous chromosomal and/or plasmid-borne genes, encoding diverse…”
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An antiplasmid system drives antibiotic resistance gene integration in carbapenemase-producing Escherichia coli lineages
Published in Nature communications (15-05-2024)“…Plasmids carrying antibiotic resistance genes (ARG) are the main mechanism of resistance dissemination in Enterobacterales. However, the fitness-resistance…”
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The bacterial genetic determinants of Escherichia coli capacity to cause bloodstream infections in humans
Published in PLoS genetics (02-08-2023)“…Escherichia coli is both a highly prevalent commensal and a major opportunistic pathogen causing bloodstream infections (BSI). A systematic analysis…”
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Is the discopathy associated with Modic changes an infectious process? Results from a prospective monocenter study
Published in PloS one (15-08-2019)“…The local infectious origin and the putative role of Cutibacterium acnes (CA) of a particular subtype of discopathy (Modic 1) are still debated. To establish…”
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Phylogroup stability contrasts with high within sequence type complex dynamics of Escherichia coli bloodstream infection isolates over a 12-year period
Published in Genome medicine (05-05-2021)“…Escherichia coli is the leading cause of bloodstream infections, associated with a significant mortality. Recent genomic analyses revealed that few clonal…”
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Prospective Comparison Between Shotgun Metagenomics and Sanger Sequencing of the 16S rRNA Gene for the Etiological Diagnosis of Infections
Published in Frontiers in microbiology (06-04-2022)“…Bacteriological diagnosis is traditionally based on culture. However, this method may be limited by the difficulty of cultivating certain species or by prior…”
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Ampicillin-susceptible Enterococcus faecium infections: clinical features, causal clades, and contribution of MALDI-TOF to early detection
Published in Microbiology spectrum (01-10-2023)“…ABSTRACT Enterococcus faecium, a common resident of the human gastrointestinal tract, is also a major pathogen. Prompt initiation of appropriate treatment is…”
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Modulated Response of Aspergillus fumigatus and Stenotrophomonas maltophilia to Antimicrobial Agents in Polymicrobial Biofilm
Published in Frontiers in cellular and infection microbiology (06-10-2020)“…The complexity of biofilms constitutes a therapeutic challenge and the antimicrobial susceptibility of fungal-bacterial biofilms remains poorly studied. The…”
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Genotypic and phenotypic characteristics of Escherichia coli involved in transfusion‐transmitted bacterial infections: implications for preventive strategies
Published in Transfusion (Philadelphia, Pa.) (01-08-2018)“…BACKGROUND Transfusion‐transmitted bacterial infections (TTBIs) are the main residual infectious complications of transfusions. Escherichia coli and platelet…”
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The Population Genomics of Increased Virulence and Antibiotic Resistance in Human Commensal Escherichia coli over 30 Years in France
Published in Applied and environmental microbiology (09-08-2022)“…Escherichia coli is a commensal species of the lower intestine but is also a major pathogen causing intestinal and extraintestinal infections that is…”
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Emergence of Resistance to Carbapenems Should Not Be Considered the Only Marker of Good Practices in Antibiotic Stewardship
Published in Clinical infectious diseases (01-11-2020)Get full text
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The bacterial genetic determinants of Escherichia coli capacity to cause bloodstream infections in humans
Published in PLoS genetics (02-08-2023)“…Escherichia coli is both a highly prevalent commensal and a major opportunistic pathogen causing bloodstream infections (BSI). A systematic analysis…”
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Evidence of Sexual Transmission of Extended-Spectrum β-Lactamase–Producing Enterobacterales: A Cross-sectional and Prospective Study
Published in Clinical infectious diseases (01-11-2022)“…Abstract Background Extended-spectrum β-lactamase–producing Enterobacterales (ESBL-E) represent a major threat to public health. Little is known on their…”
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Evidence of Sexual Transmission of Extended-Spectrum β-Lactamase–Producing Enterobacterales: A Cross-sectional and Prospective Study
Published in Clinical infectious diseases (01-11-2022)“…Abstract Background Extended-spectrum β-lactamase–producing Enterobacterales (ESBL-E) represent a major threat to public health. Little is known on their…”
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Colistin resistance in Parisian inpatient faecal Escherichia coli as the result of two distinct evolutionary pathways
Published in Journal of antimicrobial chemotherapy (01-06-2019)“…Beyond plasmid-encoded resistance (mcr genes) prevalence in strain collections, large epidemiological studies to estimate the human burden of…”
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Emergence of Resistance to Carbapenems Should Not Be Considered the Only Marker of Good Practices in Antibiotic Stewardship
Published in Clinical infectious diseases (03-12-2020)Get full text
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Genetic and Phenotypic Study of the \emphPectobacterium\emph Versatile Beta-Lactamase, the Enzyme Most Similar to the Plasmid-Encoded TEM-1
Published in Applied and environmental microbiology (2022)“…This study aimed to compare the chromosomal beta-lactamase from Pectobacterium versatile , PEC-1, with the well-known and globally distributed TEM-1 in terms…”
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