Search Results - "Royce, S. G."

Anti‐fibrotic actions of relaxin by Samuel, C S, Royce, S G, Hewitson, T D, Denton, K M, Cooney, T E, Bennett, R G

“…Fibrosis refers to the hardening or scarring of tissues that usually results from aberrant wound healing in response to organ injury, and its manifestations in…”
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A prospective open clinical trial of a proton pump inhibitor, elimination diet and/or budesonide for eosinophilic oesophagitis by Philpott, H., Nandurkar, S., Royce, S. G., Thien, F., Gibson, P. R.

“…Summary Background Elimination diets and high‐dose proton pump inhibitors (PPI) are advocated as first‐line treatments in patients with eosinophilic…”
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Allergy tests do not predict food triggers in adult patients with eosinophilic oesophagitis. A comprehensive prospective study using five modalities by Philpott, H., Nandurkar, S., Royce, S. G., Thien, F., Gibson, P. R.

“…Summary Background The use of allergy tests to guide dietary treatment for eosinophilic oesophagitis (EoE) is controversial and data are limited. Aeroallergen…”
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Liver fluke-associated and sporadic cholangiocarcinoma: an immunohistochemical study of bile duct, peribiliary gland and tumour cell phenotypes by Hughes, N R, Pairojkul, C, Royce, S G, Clouston, A, Bhathal, P S

“…Aim: To compare cell phenotypes displayed by cholangiocarcinomas and adjacent bile duct lesions in patients from an area endemic in liver-fluke infestation and…”
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The role of SMAD4 in early-onset colorectal cancer by Royce, S. G., Alsop, K., Haydon, A., Mead, L., Smith, L. D., Tesoriero, A. A., Giles, G. G., Jenkins, M. A., Hopper, J. L., Southey, M. C.

“…Objective  Chromosomal loss within the region of 18q and loss of SMAD4 expression have been reported to be frequent somatic events during colorectal cancer…”
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BRCA1 promoter deletions in young women with breast cancer and a strong family history: A population-based study by Smith, L.D, Tesoriero, A.A, Ramus, S.J, Dite, G, Royce, S.G, Giles, G.G, McCredie, M.R.E, Hopper, J.L, Southey, M.C

“…Abstract Women diagnosed with breast cancer before the age of 40 years who have a strong family history of breast and/or ovarian cancer were selected from an…”
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Combining an epithelial repair factor and anti‐fibrotic with a corticosteroid offers optimal treatment for allergic airways disease by Patel, K P, Giraud, A S, Samuel, C S, Royce, S G

“…Background and Purpose We evaluated the extent to which individual versus combination treatments that specifically target airway epithelial damage [trefoil…”
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Hexarelin targets neuroinflammatory pathways to preserve cardiac morphology and function in a mouse model of myocardial ischemia-reperfusion by McDonald, H., Peart, J., Kurniawan, N.D., Galloway, G., Royce, S.G., Samuel, C.S., Chen, C.

“…[Display omitted] •Lack of therapies addressing reperfusion injury in myocardial infarction patients.•Inflammation important component of myocardial ischemic…”
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Risk factors for eosinophilic esophagitis by Philpott, H., Nandurkar, S., Royce, S. G., Thien, F., Gibson, P. R.

“…Summary Eosinophilic esophagitis (EoE) is a chronic antigen driven disease, whereby food and/or aeroallergens result in inflammation and luminal narrowing, and…”
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Letter: seasonality in eosinophilic oesophagitis and food bolus obstruction – what about recurrent episodes? by Philpott, H., Nandurkar, S., Royce, S. G., Gibson, P. R.

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Intranasally administered serelaxin abrogates airway remodelling and attenuates airway hyperresponsiveness in allergic airways disease by Royce, S. G., Lim, C. X. F., Patel, K. P., Wang, B., Samuel, C. S., Tang, M. L. K.

“…Summary Background The peptide hormone relaxin plays a key role in the systemic hemodynamic and renovascular adaptive changes that occur during pregnancy,…”
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Seasonal recurrence of food bolus obstruction in eosinophilic esophagitis by Philpott, H. L., Nandurkar, S., Thien, F., Bloom, S., Lin, E., Goldberg, R., Boyapati, R., Finch, A., Royce, S. G., Gibson, P. R.

“…Background Eosinophilic esophagitis (EoE) is a newly recognised condition that is apparently increasing in prevalence, and the aetiology is poorly understood…”
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A29 INFLAMMATION AND MECHANISMS OF AIRWAY SMOOTH MUSCLE CONTRACTION: Serelaxin Is A Novel Potent Bronchodilator In Rat Precision Cut Lung Slices (pcls) And Trachea by Bourke, J E, Royce, S G, Donovan, C, Jelinic, M, Parry, L, Samuel, C, Lam, M

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C67 FUNCTIONAL MAPPING OF SMOOTH MUSCLE CONTRACTOME AND RELAXOME: Differential Inhibition Of Airway Contraction By Relaxin And Rosiglitazone by Bourke, J E, Lam, M, Samuel, C S, Royce, S G

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D25 NEONATAL AND CONGENITAL LUNG DISEASES: Il-1ra Protects Against Impaired Alveolar Development And Airway Fibrosis But Not Airway Hyperresponsiveness In A Mouse Model Of Bronchopulmonary Dysplasia by Bourke, J E, Royce, S G, Lamanna, E, Lam, M, Donovan, C, Bui, C, Nold, M, Nold, C

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A21 THE MESENCHYME AND THE EPITHELIUM IN AIRWAY INFLAMMATION: Expression And Function Of A Novel Membrane-Spanning Protein, Ms4a8b, In The Airway Epithelium by Kuek, L, Blume, C, Leffler, M, Warner, J A, Royce, S G, Howarth, P H, Stewart, A G, Davies, D E, Hulett, M D, Mackay, G A

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Vertebrate phylogeny of antigen D10: identification of a conserved foregut cell lineage by Royce, S G, Hughes, N R, Binos, S, Underwood, J R, Bhathal, P S

“…The monoclonal antibody 5HL-5D11-D10 to antigen D10 identifies a cell lineage that is restricted to certain tissues of the human foregut. We investigated the…”
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Low somatic K- ras mutation frequency in colorectal cancer diagnosed under the age of 45 years by Alsop, Kathryn, Mead, Leeanne, Smith, Letitia D., Royce, Simon G., Tesoriero, Andrea A., Young, Joanne P., Haydon, Andrew, Grubb, Garry, Giles, Graham G., Jenkins, Mark A., Hopper, John L., Southey, Melissa C.

“…Somatic mutation of K- ras is known to be a common event in colorectal cancer tumourigenesis however its association with age at onset has not been widely…”
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Use of Molecular Tumor Characteristics to Prioritize Mismatch Repair Gene Testing in Early-Onset Colorectal Cancer by SOUTHEY, Melissa C, JENKINS, Mark A, WALSH, Michael D, BARKER, Melissa A, YOUNG, Joanne P, JASS, Jeremy R, JOHN, D. James B. St, MACRAE, Finlay A, GILES, Graham G, HOPPER, John L, MEAD, Leeanne, WHITTY, Jonathan, TRIVETT, Melanie, TESORIERO, Andrea A, SMITH, Letitia D, JENMNGS, Kim, GRUBB, Garry, ROYCE, Simon G

“…The relationships between mismatch repair (MMR) protein expression, microsatellite instability (MSI), family history, and germline MMR gene mutation status…”
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Endogenous Relaxin Regulates Collagen Deposition in an Animal Model of Allergic Airway Disease by Mookerjee, Ishanee, Solly, Natasha R, Royce, Simon G, Tregear, Geoffrey W, Samuel, Chrishan S, Tang, Mimi L. K

“…We examined the relationship among relaxin (a peptide hormone that stimulates collagen degradation), airway fibrosis, other changes of airway remodeling, and…”
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