Search Results - "Roy, Suki"
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1
Versatile seamless DNA vector production in E. coli using enhanced phage lambda integrase
Published in PloS one (23-09-2022)“…Seamless DNA vectors derived from bacterial plasmids are devoid of bacterial genetic elements and represent attractive alternatives for biomedical applications…”
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2
A non-viral genome editing platform for site-specific insertion of large transgenes
Published in Stem cell research & therapy (03-09-2020)“…Abstract Background The precise, functional and safe insertion of large DNA payloads into host genomes offers versatility in downstream genetic…”
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3
Cytotoxicity, Genotoxicity, and Phytotoxicity of Tannery Effluent Discharged into Palar River Basin, Tamil Nadu, India
Published in Journal of Toxicology (01-01-2015)“…Ambur, a town located on the banks of Palar River, is considered one of the most polluted areas in India and occupied by hundreds of tanneries and leather…”
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4
Isolation and characterization of tyrosinase produced by marine actinobacteria and its application in the removal of phenol from aqueous environment
Published in Frontiers in biology (2014)“…The present study was focused on screening and characterization of tyrosinase enzyme produced by marine actinobacteria and its application in phenolic…”
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5
Analysis of population heterogeneity in CHO cells by genome-wide DNA methylation analysis and by multi-modal single-cell sequencing
Published in Journal of biotechnology (10-12-2024)“…CHO cells are major hosts for the industrial production of therapeutic proteins and their production stability is of considerable economic significance. It is…”
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6
A novel λ integrase-mediated seamless vector transgenesis platform for therapeutic protein expression
Published in Nucleic acids research (19-09-2018)“…Abstract Advances in stem cell engineering, gene therapy and molecular medicine often involve genome engineering at a cellular level. However, functionally…”
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7
Genome wide association study of uric acid in Indian population and interaction of identified variants with Type 2 diabetes
Published in Scientific reports (23-02-2016)“…Abnormal level of Serum Uric Acid (SUA) is an important marker and risk factor for complex diseases including Type 2 Diabetes. Since genetic determinant of…”
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Common Variants in CLDN2 and MORC4 Genes Confer Disease Susceptibility in Patients with Chronic Pancreatitis
Published in PloS one (28-01-2016)“…A recent genome-wide association study (GWAS) identified association with variants in X-linked CLDN2 and MORC4, and PRSS1-PRSS2 loci with chronic pancreatitis…”
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9
Normative range of blood biochemical parameters in urban Indian school-going adolescents
Published in PloS one (07-03-2019)“…Adolescence is the most critical phase of human growth that radically alters physiology of the body and wherein any inconsistency can lead to serious health…”
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10
Context-dependent DNA methylation signatures in animal livestock
Published in Environmental epigenetics (2023)“…Abstract DNA methylation is an important epigenetic modification that is widely conserved across animal genomes. It is widely accepted that DNA methylation…”
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11
Multifaceted genome-wide study identifies novel regulatory loci in SLC22A11 and ZNF45 for body mass index in Indians
Published in Molecular genetics and genomics : MGG (01-07-2020)“…Obesity, a risk factor for multiple diseases (e.g. diabetes, hypertension, cancers) originates through complex interactions between genes and prevailing…”
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12
Aquatic model for engine oil degradation by rhamnolipid producing Nocardiopsis VITSISB
Published in 3 Biotech (01-04-2015)“…The present study was focused on isolation, screening, characterization and application of biosurfactant producing marine actinobacteria. Twenty actinobacteria…”
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13
Genomewide association study for C-reactive protein in Indians replicates known associations of common variants
Published in Journal of genetics (01-03-2019)“…Elevated C-reactive protein (CRP) serves as an independent biomarker for acute and chronic inflammation, and is also associated with metabolic diseases…”
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14
Genome-Wide Association Study of Metabolic Syndrome Reveals Primary Genetic Variants at CETP Locus in Indians
Published in Biomolecules (Basel, Switzerland) (30-07-2019)“…Indians, a rapidly growing population, constitute vast genetic heterogeneity to that of Western population; however they have become a sedentary population in…”
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Genomewide association study of C-peptide surfaces key regulatory genes in Indians
Published in Journal of genetics (01-03-2019)“…Insulin is a commonly used measure of pancreatic β -cell function but exhibits a short half-life in the human body. During biosynthesis, insulin release is…”
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