Search Results - "Roy, Soumya Singha"

Noncovalent Catalysis for Enantioselective Direct Aldol Reaction of 3‐Acetylcoumarins to Pyrazole‐4,5‐diones by Ray, Bidisha, Singha Roy, Soumya Jyoti, Mukherjee, Santanu

“…The first catalytic enantioselective direct aldol reaction of 3‐acetylcoumarins to pyrazole‐4,5‐diones is reported and shown to proceed through noncovalent…”
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Photoredox‐Catalyzed Labeling of Hydroxyindoles with Chemoselectivity (PhotoCLIC) for Site‐Specific Protein Bioconjugation by Singha Roy, Soumya Jyoti, Loynd, Conor, Jewel, Delilah, Canarelli, Sarah E., Ficaretta, Elise D., Pham, Quan A., Weerapana, Eranthie, Chatterjee, Abhishek

“…We have developed a novel visible‐light‐catalyzed bioconjugation reaction, PhotoCLIC, that enables chemoselective attachment of diverse aromatic amine reagents…”
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A Nuclear Singlet Lifetime of More than One Hour in Room-Temperature Solution by Stevanato, Gabriele, Hill-Cousins, Joseph T., Håkansson, Pär, Roy, Soumya Singha, Brown, Lynda J., Brown, Richard C. D., Pileio, Giuseppe, Levitt, Malcolm H.

“…Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are supremely important techniques with numerous applications in almost all branches of…”
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"On water" catalytic enantioselective sulfenylation of deconjugated butyrolactams by Singha Roy, Soumya Jyoti, Mukherjee, Santanu

“…The first catalytic enantioselective α-sulfenylation of deconjugated butyrolactams has been developed using dimeric cinchona alkaloids as catalysts in a…”
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Catalytic Enantioselective C–C Bond-Forming Reactions of Deconjugated Butyrolactams: Michael Addition to α,β-Unsaturated Aldehydes and Ketones by Singha Roy, Soumya Jyoti, Mukherjee, Santanu

“…Nucleophilic reactivity of deconjugated butyrolactams has been demonstrated for enantioselective Michael additions to α,β-unsaturated aldehydes and ketones…”
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Electrochemical labelling of hydroxyindoles with chemoselectivity for site-specific protein bioconjugation by Loynd, Conor, Singha Roy, Soumya Jyoti, Ovalle, Vincent J., Canarelli, Sarah E., Mondal, Atanu, Jewel, Delilah, Ficaretta, Elise D., Weerapana, Eranthie, Chatterjee, Abhishek

“…Electrochemistry has recently emerged as a powerful approach in small-molecule synthesis owing to its numerous attractive features, including precise control…”
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Functional Investigations of p53 Acetylation Enabled by Heterobifunctional Molecules by Chen, Li-Yun, Singha Roy, Soumya Jyoti, Jadhav, Appaso M., Wang, Wesley W., Chen, Pei-Hsin, Bishop, Timothy, Erb, Michael A., Parker, Christopher G.

“…Post-translational modifications (PTMs) dynamically regulate the critical stress response and tumor suppressive functions of p53. Among these, acetylation…”
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An Efficient Opal‐Suppressor Tryptophanyl Pair Creates New Routes for Simultaneously Incorporating up to Three Distinct Noncanonical Amino Acids into Proteins in Mammalian Cells by Osgood, Arianna O., Zheng, Yunan, Roy, Soumya Jyoti Singha, Biris, Nikolaos, Hussain, Myer, Loynd, Conor, Jewel, Delilah, Italia, James S., Chatterjee, Abhishek

“…Site‐specific incorporation of multiple distinct noncanonical amino acids (ncAAs) into proteins in mammalian cells is a promising technology, where each ncAA…”
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Density matrix tomography of singlet states by Singha Roy, Soumya, Mahesh, T.S.

“…First direct and quantitative study of singlet states using density matrix tomography is reported. A robust scheme for the tomography of a general density…”
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Photoredox‐Catalyzed Labeling of Hydroxyindoles with Chemoselectivity (PhotoCLIC) for Site‐Specific Protein Bioconjugation by Singha Roy, Soumya Jyoti, Loynd, Conor, Jewel, Delilah, Canarelli, Sarah E., Ficaretta, Elise D., Pham, Quan A., Weerapana, Eranthie, Chatterjee, Abhishek

“…We have developed a novel visible‐light‐catalyzed bioconjugation reaction, PhotoCLIC, that enables chemoselective attachment of diverse aromatic amine reagents…”
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An Efficient Opal‐Suppressor Tryptophanyl Pair Creates New Routes for Simultaneously Incorporating up to Three Distinct Noncanonical Amino Acids into Proteins in Mammalian Cells by Osgood, Arianna O., Zheng, Yunan, Roy, Soumya Jyoti Singha, Biris, Nikolaos, Hussain, Myer, Loynd, Conor, Jewel, Delilah, Italia, James S., Chatterjee, Abhishek

“…Site‐specific incorporation of multiple distinct noncanonical amino acids (ncAAs) into proteins in mammalian cells is a promising technology, where each ncAA…”
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A Diversity-Oriented Synthesis of Bicyclic cis-Dihydroarenediols, cis-4-Hydroxyscytalones, and Bicyclic Conduritol Analogues by Mukherjee, Parag, Roy, Soumya J. Singha, Sarkar, Tarun K.

“…A common-intermediate-based enantioselective strategy has been developed aiming at bicyclic arene cis-dihydrodiols, cis-4-hydroxyscytalones, and bicyclic…”
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A Nuclear Singlet Lifetime of More than One Hour in Room-Temperature Solution by Stevanato, Gabriele, Hill-Cousins, Joseph T., Håkansson, Pär, Roy, Soumya Singha, Brown, Lynda J., Brown, Richard C. D., Pileio, Giuseppe, Levitt, Malcolm H.

“…Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are supremely important techniques with numerous applications in almost all branches of…”
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Investigation of the Leggett-Garg inequality for precessing nuclear spins by Athalye, Vikram, Roy, Soumya Singha, Mahesh, T S

“…We report experimental implementation of a protocol for testing the Leggett-Garg inequality (LGI) for nuclear spins precessing in an external magnetic field…”
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Native Aminoacyl-tRNA Synthetase/tRNA Pair Drives Highly Efficient Noncanonical Amino Acid Incorporation in Escherichia coli by Ficaretta, Elise D., Singha Roy, Soumya Jyoti, Voss, Lena, Chatterjee, Abhishek

“…Site-specific noncanonical amino acid (ncAA) mutagenesis in living cells has traditionally relied on heterologous, nonsense-suppressing aminoacyl-tRNA…”
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Initialization of NMR quantum registers using long-lived singlet states by Roy, Soumya Singha, Mahesh, T. S.

“…An ensemble of nuclear spin pairs under certain conditions is known to exhibit singlet state lifetimes much longer than other nonequilibrium states. This…”
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Long-Lived Nuclear Spin States in Methyl Groups and Quantum-Rotor-Induced Polarization by Meier, Benno, Dumez, Jean-Nicolas, Stevanato, Gabriele, Hill-Cousins, Joseph T, Roy, Soumya Singha, Håkansson, Pär, Mamone, Salvatore, Brown, Richard C. D, Pileio, Giuseppe, Levitt, Malcolm H

“…Substances containing rapidly rotating methyl groups may exhibit long-lived states (LLSs) in solution, with relaxation times substantially longer than the…”
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Storing entanglement of nuclear spins via Uhrig dynamical decoupling by Roy, Soumya Singha, Mahesh, T. S., Agarwal, G. S.

“…Stroboscopic spin flips have already been shown to prolong the coherence times of quantum systems under noisy environments. Uhrig's dynamical decoupling scheme…”
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Directed Evolution of a Bacterial Leucyl tRNA in Mammalian Cells for Enhanced Noncanonical Amino Acid Mutagenesis by Huang, Rachel L., Jewel, Delilah, Kelemen, Rachel E., Pham, Quan, Yared, Tarah J., Wang, Shu, Singha Roy, Soumya Jyoti, Huang, Zeyi, Levinson, Samantha D., Sundaresh, Bharathi, Miranda, Suyen Espinoza, van Opijnen, Tim, Chatterjee, Abhishek

“…The Escherichia coli leucyl-tRNA synthetase (EcLeuRS)/tRNAEcLeu pair has been engineered to genetically encode a structurally diverse group of enabling…”
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A Genetically Encoded Photocaged Cysteine for Facile Site-Specific Introduction of Conjugation-Ready Thiol Residues in Antibodies by Osgood, Arianna O., Roy, Soumya Jyoti Singha, Koo, David, Gu, Renpeng, Chatterjee, Abhishek

“…Antibody–drug conjugates (ADCs) have emerged as a powerful class of anticancer therapeutics that enable the selective delivery of toxic payloads into target…”
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