Search Results - "Roy, Monideepa"

Role of BRCA Mutations in the Modulation of Response to Platinum Therapy by Mylavarapu, Sanghamitra, Das, Asmita, Roy, Monideepa

“…Recent years have seen cancer emerge as one of the leading cause of mortality worldwide with breast cancer being the second most common cause of death among…”
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IQGAP1 Is a Scaffold for Mitogen-Activated Protein Kinase Signaling by Roy, Monideepa, Li, Zhigang, Sacks, David B.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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1166 Preclinical evaluation of lintuzumab-Ac225, a CD33 antibody radioconjugate targeting myeloid-derived suppressor cells by Chin, Amanda, Chen, Mary, Lewis, Debbie, Mukherjee, Sumit, Li, Jason, Xu, Le-Cun, Roy, Monideepa, Brodin, Patrik, Touw, William van der, Beckford-Vera, Denis, Kotanides, Helen

“…BackgroundMyeloid-derived suppressor cells (MDSCs) are immunosuppressive myeloid lineage cells enriched in cancer patients. There is growing interest in the…”
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Activation of Epithelial-Mesenchymal Transition and Altered β-Catenin Signaling in a Novel Indian Colorectal Carcinoma Cell Line by Mylavarapu, Sanghamitra, Kumar, Harsh, Kumari, Smita, Sravanthi, L S, Jain, Misti, Basu, Aninda, Biswas, Manjusha, Mylavarapu, Sivaram V S, Das, Asmita, Roy, Monideepa

“…Colorectal cancer is the third major cause of cancer-related mortality worldwide. The upward trend in incidence and mortality rates, poor sensitivity to…”
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Computationally designed antibody–drug conjugates self-assembled via affinity ligands by Gupta, Nimish, Ansari, Aasif, Dhoke, Gaurao V., Chilamari, Maheshwerreddy, Sivaccumar, Jwala, Kumari, Smita, Chatterjee, Snigdha, Goyal, Ravinder, Dutta, Pradip Kumar, Samarla, Mallik, Mukherjee, Madhumita, Sarkar, Arindam, Mandal, Swadhin K., Rai, Vishal, Biswas, Goutam, Sengupta, Aniruddha, Roy, Sudip, Roy, Monideepa, Sengupta, Shiladitya

“…Antibody–drug conjugates (ADCs) combine the high specificity of antibodies with cytotoxic payloads. However, the present strategies for the synthesis of ADCs…”
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Activation Dynamics and Signaling Properties of Notch3 Receptor in the Developing Pulmonary Artery by Ghosh, Shamik, Paez-Cortez, Jesus R., Boppidi, Karthik, Vasconcelos, Michelle, Roy, Monideepa, Cardoso, Wellington, Ai, Xingbin, Fine, Alan

“…Notch3 signaling is fundamental for arterial specification of systemic vascular smooth muscle cells (VSMCs). However, the developmental role and signaling…”
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Identification of a Conserved Negative Regulatory Sequence That Influences the Leukemogenic Activity of NOTCH1 by Chiang, Mark Y., Xu, Mina L., Histen, Gavin, Shestova, Olga, Roy, Monideepa, Nam, Yunsun, Blacklow, Stephen C., Sacks, David B., Pear, Warren S., Aster, Jon C.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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IQGAP1 Binds ERK2 and Modulates Its Activity by Roy, Monideepa, Li, Zhigang, Sacks, David B.

“…IQGAP1 binds several proteins including actin, calmodulin, E-cadherin, β-catenin, Cdc42, Rac1, and CLIP-170. The interaction with these targets enables IQGAP1…”
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Author Correction: Computationally designed antibody–drug conjugates self-assembled via affinity ligands by Gupta, Nimish, Ansari, Aasif, Dhoke, Gaurao V., Chilamari, Maheshwerreddy, Sivaccumar, Jwala, Kumari, Smita, Chatterjee, Snigdha, Goyal, Ravinder, Dutta, Pradip Kumar, Samarla, Mallik, Mukherjee, Madhumita, Sarkar, Arindam, Mandal, Swadhin K., Rai, Vishal, Biswas, Goutam, Sengupta, Aniruddha, Roy, Sudip, Roy, Monideepa, Sengupta, Shiladitya

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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N-Acetylglucosamine-inducible CaGAP1 encodes a general amino acid permease which co-ordinates external nitrogen source response and morphogenesis in Candida albicans by Biswas, Subhrajit, Roy, Monideepa, Datta, Asis

“…School of Life Sciences, Jawaharlal Nehru University, New Delhi-110 067, India Correspondence Asis Datta asisdatta{at}hotmail.com Candida albicans is able to…”
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Preclinical evaluation of novel HER3-targeting radioconjugates for the imaging and treatment of HER3-expressing cancers by Beckford Vera, Denis, Li, Jason, Xu, Le-Cun, Lewis, Debbie, Chin, Amanda, Brodin, Patrik, Chen, Mary, Roy, Monideepa, Kotanides, Helen

“…e15114 Background: HER3 overexpression in tumors is associated with poor survival and is implicated in drug resistance mechanisms of HER1 (EGFR) and HER2…”
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The multifaceted role of Notch in cancer by Roy, Monideepa, Pear, Warren S, Aster, Jon C

“…The diverse roles that Notch signals play during the development and maintenance of normal tissues are recapitulated in different forms of cancer. Depending on…”
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Lintuzumab-Ac225, a CD33-Directed Antibody Radiotherapy, Targets AML in a Mutation Agnostic Manner by Chin, Amanda, Jiao, Rubin, Allen, Kevin J.H., Li, Jason, Chen, Mary, Vusirikala, Madhuri, Xu, Le-Cun, Brodin, Patrik, Roy, Monideepa, Malo, Mackenzie, Van der Touw, William, Dadachova, Ekaterina, Beckford-Vera, Denis, Kotanides, Helen

“…Introduction Acute myeloid leukemia (AML) is a highly heterogeneous hematologic malignancy with a poor survival prognosis. Recurrent gene mutations are the…”
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AML-502 Antileukemic Activity of Lintuzumab-Ac225 in Preclinical Model of FLT3 Mutant AML by Chin, Amanda, Li, Jason, Chen, Mary, Vusirikala, Madhuri, Xu, Le-Cun, Brodin, Patrik, Roy, Monideepa, Beckford-Vera, Denis, Kotanides, Helen

“…Acute myeloid leukemia (AML) is a hematologic malignancy with a poor survival prognosis. We have demonstrated promising therapeutic responses with Actimab-A…”
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POSTER: AML-502 Antileukemic Activity of Lintuzumab-Ac225 in Preclinical Model of FLT3 Mutant AML by Chin, Amanda, Li, Jason, Chen, Mary, Vusirikala, Madhuri, Xu, Le-Cun, Brodin, Patrik, Roy, Monideepa, Beckford-Vera, Denis, Kotanides, Helen

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Abstract 751: A controlled affinity-guided ADC-linker (MAGNET) technology by Gupta, Nimish, Biswas, Goutam, Sengupta, Aniruddha, Roy, Monideepa, Roy, Sudip, Sengupta, Shiladitya

“…Abstract Antibody-drug conjugates (ADCs) have emerged as a powerful technology in cancer therapy. However, challenges with current linker technologies have…”
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Abstract 4918: Pharmacokinetics and toxicity studies of AT1965, a B-cell activating immunotherapy by Sengupta, Aniruddha, Samarla, Mallik, Pandey, Manoj, Sarkar, Arindam, Roy, Monideepa, Sengupta, Shiladitya

“…Abstract Introduction: Cancer immunotherapy is the emerging paradigm in the search for a cure for cancer. AT1965 is a novel therapeutic that demonstrates…”
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Abstract 4712: AT1965, a novel B cell-activating immunotherapy, exerts potent anticancer activity by Roy, Monideepa, Krishna, Vineeth, Sengupta, Aniruddha, Roy, Sudip, Kulkarni, Ashish, Sengupta, Shiladitya

“…Abstract Emerging clinical evidence implicate B cells in long term survival in cancer. However, a therapeutic activation of a B cell response against cancer…”
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Development of a facile antibody-drug conjugate platform for increased stability and homogeneity by Gupta, Nimish, Kancharla, Johny, Kaushik, Shelly, Ansari, Aasif, Hossain, Samad, Goyal, Ravinder, Pandey, Manoj, Sivaccumar, Jwala, Hussain, Sazid, Sarkar, Arindam, Sengupta, Aniruddha, Mandal, Swadhin K, Roy, Monideepa, Sengupta, Shiladitya

“…Despite the advances in the design of antibody-drug conjugates (ADCs), the search is still ongoing for novel approaches that lead to increased stability and…”
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Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL by Gordon, Wendy R., Roy, Monideepa, Vardar-Ulu, Didem, Garfinkel, Megan, Mansour, Marc R., Aster, Jon C., Blacklow, Stephen C.

“…Proteolytic resistance of Notch prior to ligand binding depends on the structural integrity of a negative regulatory region (NRR) of the receptor that…”
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