Search Results - "Roy, Dheeraj S"

Ventral CA1 neurons store social memory by Okuyama, Teruhiro, Kitamura, Takashi, Roy, Dheeraj S., Itohara, Shigeyoshi, Tonegawa, Susumu

“…The medial temporal lobe, including the hippocampus, has been implicated in social memory. However, it remains unknown which parts of these brain regions and…”
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Engram cells retain memory under retrograde amnesia by Ryan, Tomás J., Roy, Dheeraj S., Pignatelli, Michele, Arons, Autumn, Tonegawa, Susumu

“…Memory consolidation is the process by which a newly formed and unstable memory transforms into a stable long-term memory. It is unknown whether the process of…”
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Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease by Roy, Dheeraj S., Arons, Autumn, Mitchell, Teryn I., Pignatelli, Michele, Ryan, Tomás J., Tonegawa, Susumu

“…Experiments in transgenic mouse models of early Alzheimer’s disease show that the amnesia seen at this stage of the disease is probably caused by a problem…”
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Engram Cell Excitability State Determines the Efficacy of Memory Retrieval by Pignatelli, Michele, Ryan, Tomás J., Roy, Dheeraj S., Lovett, Chanel, Smith, Lillian M., Muralidhar, Shruti, Tonegawa, Susumu

“…Animals need to optimize the efficacy of memory retrieval to adapt to environmental circumstances for survival. The recent development of memory engram…”
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Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories by Roy, Dheeraj S., Kitamura, Takashi, Okuyama, Teruhiro, Ogawa, Sachie K., Sun, Chen, Obata, Yuichi, Yoshiki, Atsushi, Tonegawa, Susumu

“…The formation and retrieval of a memory is thought to be accomplished by activation and reactivation, respectively, of the memory-holding cells (engram cells)…”
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Silent memory engrams as the basis for retrograde amnesia by Roy, Dheeraj S., Muralidhar, Shruti, Smith, Lillian M., Tonegawa, Susumu

“…Recent studies identified neuronal ensembles and circuits that hold specific memory information (memory engrams). Memory engrams are retained under protein…”
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Brain-wide mapping reveals that engrams for a single memory are distributed across multiple brain regions by Roy, Dheeraj S., Park, Young-Gyun, Kim, Minyoung E., Zhang, Ying, Ogawa, Sachie K., DiNapoli, Nicholas, Gu, Xinyi, Cho, Jae H., Choi, Heejin, Kamentsky, Lee, Martin, Jared, Mosto, Olivia, Aida, Tomomi, Chung, Kwanghun, Tonegawa, Susumu

“…Neuronal ensembles that hold specific memory (memory engrams) have been identified in the hippocampus, amygdala, or cortex. However, it has been hypothesized…”
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Synchronous Evolution of an Odor Biosynthesis Pathway and Behavioral Response by Li, Qian, Korzan, Wayne J., Ferrero, David M., Chang, Rui B., Roy, Dheeraj S., Buchi, Mélanie, Lemon, Jamie K., Kaur, Angeldeep W., Stowers, Lisa, Fendt, Markus, Liberles, Stephen D.

“…Rodents use olfactory cues for species-specific behaviors. For example, mice emit odors to attract mates of the same species, but not competitors of closely…”
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Neurons expressing trace amine-associated receptors project to discrete glomeruli and constitute an olfactory subsystem by Johnson, Mark A., Tsai, Lulu, Roy, Dheeraj S., Valenzuela, David H., Mosley, Colleen, Magklara, Angeliki, Lomvardas, Stavros, Liberles, Stephen D., Barnea, Gilad

“…Some chemoreceptors of the trace amine-associated receptor (TAAR) family detect innately aversive odors and are proposed to activate hardwired olfactory…”
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Inhibitory Central Amygdala Outputs to Thalamus Control the Gain of Taste Perception by Roy, Dheeraj S

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Memory engram storage and retrieval by Tonegawa, Susumu, Pignatelli, Michele, Roy, Dheeraj S, Ryan, Tomás J

“…Highlights • We review the history of research into putative memory storage mechanisms. • We highlight recent advances catalyzed by memory engram labeling…”
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Engrams and circuits crucial for systems consolidation of a memory by Kitamura, Takashi, Ogawa, Sachie K., Roy, Dheeraj S., Okuyama, Teruhiro, Morrissey, Mark D., Smith, Lillian M., Redondo, Roger L., Tonegawa, Susumu

“…Episodic memories initially require rapid synaptic plasticity within the hippocampus for their formation and are gradually consolidated in neocortical networks…”
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Thalamic subnetworks as units of function by Roy, Dheeraj S., Zhang, Ying, Halassa, Michael M., Feng, Guoping

“…The thalamus engages in various functions including sensory processing, attention, decision making and memory. Classically, this diversity of function has been…”
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Finding pleasure in repetitive behaviors by Zhang, Ying, Roy, Dheeraj S., Feng, Guoping

“…In this issue of Neuron, Sun et al. (2022) identify a neuronal subpopulation in the medial paralemniscal nucleus that underlies repetitive self-grooming…”
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Dynamic and selective engrams emerge with memory consolidation by Tomé, Douglas Feitosa, Zhang, Ying, Aida, Tomomi, Mosto, Olivia, Lu, Yifeng, Chen, Mandy, Sadeh, Sadra, Roy, Dheeraj S., Clopath, Claudia

“…Episodic memories are encoded by experience-activated neuronal ensembles that remain necessary and sufficient for recall. However, the temporal evolution of…”
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Anterior thalamic circuits crucial for working memory by Roy, Dheeraj S, Zhang, Ying, Aida, Tomomi, Shen, Chenjie, Skaggs, Keith M, Hou, Yuanyuan, Fleishman, Morgan, Mosto, Olivia, Weninger, Alyssa, Feng, Guoping

“…Alterations in the structure and functional connectivity of anterior thalamic nuclei (ATN) have been linked to reduced cognition during aging. However, ATN…”
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Memory Storage in Distributed Engram Cell Ensembles by Zhang, Ying, Roy, Dheeraj S

“…One of the most fascinating aspects of the brain is its ability to acquire new information from experience and retain it over time as memory. The search for…”
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Tagging activated neurons with light by Roy, Dheeraj S, Okuyama, Teruhiro, Tonegawa, Susumu

“…Two new protein tools translate neuronal activity into gene expression during a light-defined time window…”
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A juvenile mouse pheromone inhibits sexual behaviour through the vomeronasal system by Ferrero, David M., Moeller, Lisa M., Osakada, Takuya, Horio, Nao, Li, Qian, Roy, Dheeraj S., Cichy, Annika, Spehr, Marc, Touhara, Kazushige, Liberles, Stephen D.

“…ESP22, a new pheromone produced by juvenile mice before puberty and released through the tears, activates neurons in the vomeronasal organ and inhibits mating…”
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Targeting thalamic circuits rescues motor and mood deficits in PD mice by Zhang, Ying, Roy, Dheeraj S., Zhu, Yi, Chen, Yefei, Aida, Tomomi, Hou, Yuanyuan, Shen, Chenjie, Lea, Nicholas E., Schroeder, Margaret E., Skaggs, Keith M., Sullivan, Heather A., Fischer, Kyle B., Callaway, Edward M., Wickersham, Ian R., Dai, Ji, Li, Xiao-Ming, Lu, Zhonghua, Feng, Guoping

“…Although bradykinesia, tremor and rigidity are the hallmark motor defects in patients with Parkinson’s disease (PD), patients also experience motor learning…”
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