Search Results - "Roy, Debarshi"

Development and Validation of an Empirical Model-based Instrument to Measure Empathy-driven Organizational Cultures in Indian Schools by Roy, Debarshi

“…It has been widely acknowledged that empathy plays an important role in school education, but empathy as a part of school organizational culture has not been…”
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Development and Validation of a Scale for Psychological Safety in School Among High School Students in India by Roy, Debarshi

“…The concept of psychological safety in the workplace is becoming increasingly important to organizational culture and planning. Kahn (1990, Academy of…”
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Nuclear localization of histamine receptor 2 in primary human lymphatic endothelial cells by Pal, Sarit, Gashev, Anatoliy, Roy, Debarshi

“…Histamine exerts its physiological functions through its four receptor subtypes. In this work, we report the subcellular localization of histamine receptor 2…”
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Anticancer Properties of Kaempferol on Cellular Signaling Pathways by Sengupta, Bidisha, Biswas, Pragnya, Roy, Debarshi, Lovett, Justin, Simington, Laken, Fry, Darrell R, Travis, Kaelin

“…Polyhydroxy compounds are secondary metabolites that are ubiquitous in plants of higher genera. They possess therapeutic properties against a wide spectrum of…”
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PFKFB3 inhibition reprograms malignant pleural mesothelioma to nutrient stress-induced macropinocytosis and ER stress as independent binary adaptive responses by Sarkar Bhattacharya, Sayantani, Thirusangu, Prabhu, Jin, Ling, Roy, Debarshi, Jung, Deokbeom, Xiao, Yinan, Staub, Julie, Roy, Bhaskar, Molina, Julian R., Shridhar, Viji

“…The metabolic signatures of cancer cells are often associated with elevated glycolysis. Pharmacological (PFK158 treatment) and genetic inhibition of…”
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Group III phospholipase A2 downregulation attenuated survival and metastasis in ovarian cancer and promotes chemo-sensitization by Ray, Upasana, Roy, Debarshi, Jin, Ling, Thirusangu, Prabhu, Staub, Julie, Xiao, Yinan, Kalogera, Eleftheria, Wahner Hendrickson, Andrea E, Cullen, Grace D, Goergen, Krista, Oberg, Ann L, Shridhar, Viji

“…Abstract Background Aberrant lipogenicity and deregulated autophagy are common in most advanced human cancer and therapeutic strategies to exploit these…”
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Quinacrine in endometrial cancer: Repurposing an old antimalarial drug by Kalogera, Eleftheria, MD, Roy, Debarshi, Ph.D, Khurana, Ashwani, Ph.D, Mondal, Susmita, Ph.D, Weaver, Amy L., MS, He, Xiaoping, MD. Ph.D, Dowdy, Sean C., MD, Shridhar, Viji, Ph.D

“…Highlights • Quinacrine exhibited strong antitumor activity against endometrial cancer in vitro. • Quinacrine with cisplatin or paclitaxel exhibited strong…”
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Transepithelial Anti-Neuroblastoma Response to Kale among Four Vegetable Juices Using In Vitro Model Co-Culture System by Piletz, John E, Mao, Yuhan, Roy, Debarshi, Qizilbash, Bilal, Nkamssi, Eurielle, Weir, Enleyona, Graham, Jessica, Emmanuel, Mary, Iqbal, Suwaira, Brue, Kellie, Sengupta, Bidisha

“…Juicing vegetables is thought to be an anticancer treatment. Support exists for a rank order of anticancer greens (kale > dandelion > lettuce > spinach) based…”
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Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer by Roy, Debarshi, Mondal, Susmita, Khurana, Ashwani, Jung, Deok-Beom, Hoffmann, Robert, He, Xiaoping, Kalogera, Eleftheria, Dierks, Thomas, Hammond, Edward, Dredge, Keith, Shridhar, Viji

“…Defective autophagy and deranged metabolic pathways are common in cancer; pharmacologic targeting of these two pathways could provide a viable therapeutic…”
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EF24 prevents rotenone-induced estrogenic status alteration in breast cancer by Roy, Debarshi, Kabiraj, Parijat, Pal, Rituraj

“…Protein disulfide isomerase (PDI), an important endoplasmic reticulum‐resident oxidoreductase chaperone can bind to estrogens as well as intact with its…”
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Health disparity and COVID‐19—A retrospective analysis by Sarkar, Sanjay, Taylor, Archie, Dutta, Pratik, Bajaj, Meghna, Nash, Justin, Ravola, Martha, Ievleva, Sofia, Llyod, Cardarius, Ola, Praise, Jenkins, Brenita, Sengupta, Bidisha, Roy, Debarshi

“…Background and Aims According to the World Health Organization (WHO), more than 75.7 million confirmed cases of coronavirus disease 2019 (COVID‐19), a global…”
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Entrepreneurship-driven Migratory Behaviour Among the Tea Estate Workers in West Bengal: An Exploratory Study by Roy, Debarshi

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Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer by Roy, Debarshi, Mondal, Susmita, Wang, Chen, He, Xiaoping, Khurana, Ashwani, Giri, Shailendra, Hoffmann, Robert, Jung, Deok-Beom, Kim, Sung H, Chini, Eduardo N, Periera, Juliana Camacho, Folmes, Clifford D, Mariani, Andrea, Dowdy, Sean C, Bakkum-Gamez, Jamie N, Riska, Shaun M, Oberg, Ann L, Karoly, Edward D, Bell, Lauren N, Chien, Jeremy, Shridhar, Viji

“…Loss of the endosulfatase HSulf-1 is common in ovarian cancer, upregulates heparin binding growth factor signaling and potentiates tumorigenesis and…”
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Caveolin-1 and lipids: Association and their dualism in oncogenic regulation by Bhowmick, Sramana, Biswas, Tannishtha, Ahmed, Mehnaz, Roy, Debarshi, Mondal, Susmita

“…Caveolin-1 (Cav-1) is a structural protein of caveolae that functions as a molecular organizer for different cellular functions including endocytosis and…”
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Studying nanoscale structural alterations in cancer cells to evaluate ovarian cancer drug treatment, using transmission electron microscopy imaging by Adhikari, Prakash, Hasan, Mehedi, Sridhar, Vijayalakshmi, Roy, Debarshi, Pradhan, Prabhakar

“…Understanding nanoscale structural changes can provide information about the physical state of cells/tissues. It has now been shown that increases in nanoscale…”
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Lymphatic vasculature in ovarian cancer by Pal, Sarit, Bhowmick, Sramana, Sharma, Anurag, Sierra-Fonseca, Jorge A., Mondal, Susmita, Afolabi, Favour, Roy, Debarshi

“…Ovarian cancer (OVCA) is the second most common gynecological cancer and one of the leading causes of cancer related mortality among women. Recent studies…”
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Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers by Mondal, Susmita, Roy, Debarshi, Sarkar Bhattacharya, Sayantani, Jin, Ling, Jung, Deokbeom, Zhang, Song, Kalogera, Eleftheria, Staub, Julie, Wang, Yaxian, Xuyang, Wen, Khurana, Ashwani, Chien, Jeremey, Telang, Sucheta, Chesney, Jason, Tapolsky, Gilles, Petras, Dzeja, Shridhar, Viji

“…Metabolic alterations are increasingly recognized as important novel anti‐cancer targets. Among several regulators of metabolic alterations, fructose 2,6…”
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Abstract 1936: Autophagy-dependent therapeutic targeting of group III phospholipase A2 attenuates ovarian cancer metastasis by Ray, Upasana, Roy, Debarshi, Jin, Ling, Thirusangu, Prabhu, Staub, Julie, Xiao, Yinan, Shridhar, Viji

“…Abstract Objective: Aberrant lipogenicity and deregulated autophagy are common in most advanced human cancer and therapeutic strategies to exploit these…”
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Quinacrine upregulates p21/p27 independent of p53 through autophagy-mediated downregulation of p62-Skp2 axis in ovarian cancer by Jung, DeokBeom, Khurana, Ashwani, Roy, Debarshi, Kalogera, Eleftheria, Bakkum-Gamez, Jamie, Chien, Jeremy, Shridhar, Viji

“…We have previously shown that the anti-malarial compound Quinacrine (QC) inhibits ovarian cancer (OC) growth by modulating autophagy. In the present study we…”
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Sulfated glycolipid PG545 induces endoplasmic reticulum stress and augments autophagic flux by enhancing anticancer chemotherapy efficacy in endometrial cancer by Hoffmann, Robert, Sarkar Bhattacharya, Sayantani, Roy, Debarshi, Winterhoff, Boris, Schmidmaier, Ralf, Dredge, Keith, Hammond, Edward, Shridhar, Viji

“…[Display omitted] •PG545 synergizes with cisplatin or paclitaxel in vitro.•PG545 in combination with paclitaxel and cisplatin exhibited strong antitumor…”
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