Search Results - "Roxana Mehran, MD"
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Prosthetic Heart Valve Thrombosis
Published in Journal of the American College of Cardiology (20-12-2016)“…Abstract Although surgery was the mainstay of treatment for valvular heart disease, transcatheter valve therapies have grown exponentially over the past…”
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In-Stent Restenosis in the Drug-Eluting Stent Era
Published in Journal of the American College of Cardiology (30-11-2010)“…The introduction of the drug-eluting stent (DES) proved to be an important step forward in reducing rates of restenosis and target lesion revascularization…”
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Incidence, Predictors, and Impact of Post-Discharge Bleeding After Percutaneous Coronary Intervention
Published in Journal of the American College of Cardiology (01-09-2015)“…Abstract Background The incidence, predictors, and prognostic impact of post-discharge bleeding (PDB) after percutaneous coronary intervention (PCI) with…”
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Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study
Published in The Lancet (British edition) (17-08-2013)“…Summary Background The relation between platelet reactivity and stent thrombosis, major bleeding, and other adverse events after coronary artery implantation…”
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Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer
Published in Journal of allergy and clinical immunology (01-12-2016)“…Murine models of anaphylaxis have suggested that IgG antibody/allergen complexes interacting with Fcγ receptors on basophils and neutrophils release…”
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An open-label, randomized, controlled, multicenter study exploring two treatment strategies of rivaroxaban and a dose-adjusted oral vitamin k antagonist treatment strategy in subjects with atrial fibrillation who undergo percutaneous coronary intervention (PIONEER AF-PCI)
Published in The American heart journal (01-04-2015)“…Background Guidelines recommendations regarding anticoagulant therapy after percutaneous coronary intervention (PCI) among patients with atrial fibrillation…”
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A Risk Score to Predict Bleeding in Patients With Acute Coronary Syndromes
Published in Journal of the American College of Cardiology (08-06-2010)“…Objectives The aim of this study was to develop a practical risk score to predict the risk and implications of major bleeding in acute coronary syndromes…”
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Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention: Rationale and Design of the TWILIGHT Study
Published in The American heart journal (01-12-2016)“…Abstract Background Dual antiplatelet therapy (DAPT) is necessary to prevent thrombosis yet increases bleeding after percutaneous coronary intervention (PCI)…”
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Short-Term Rosuvastatin Therapy for Prevention of Contrast-Induced Acute Kidney Injury in Patients With Diabetes and Chronic Kidney Disease
Published in Journal of the American College of Cardiology (01-01-2014)“…Objectives This study sought to evaluate the safety and efficacy of rosuvastatin in preventing contrast-induced acute kidney injury (CI-AKI) in patients with…”
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Risk scores in acute coronary syndrome and percutaneous coronary intervention: A review
Published in The American heart journal (01-04-2013)“…Patients with acute coronary syndrome (ACS) need to be risk stratified to deliver the most appropriate therapy. The GRACE and TIMI risk scores have penetrated…”
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Impact of Coronary Lesion Complexity on Drug-Eluting Stent Outcomes in Patients With and Without Diabetes Mellitus
Published in Journal of the American College of Cardiology (27-05-2014)“…Objectives The aim of this study was to investigate whether baseline lesion complexity affects drug-eluting stent (DES) outcomes according to diabetic status…”
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Relation of Baseline Hemoglobin Levels and Adverse Events in Patients with Acute Coronary Syndromes (from the ACUITY and HORIZONS-AMI Trials)
Published in The American journal of cardiology (01-06-2017)“…The association between anemia at admission and adverse outcomes in patients with acute coronary syndromes (ACS) has been incompletely studied. Anemia was…”
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Comparison of Outcomes and Prognosis of Patients With versus Without Newly Diagnosed Diabetes Mellitus After Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction (The HORIZONS-AMI Study)
Published in The American journal of cardiology (15-06-2017)“…A history of diabetes mellitus (DM) is an independent predictor for adverse events in patients with acute STEMI undergoing primary percutaneous coronary…”
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Impact of Atrial Fibrillation in Patients With ST-Elevation Myocardial Infarction Treated With Percutaneous Coronary Intervention (from the HORIZONS-AMI [Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction] Trial)
Published in The American journal of cardiology (15-01-2014)“…Atrial fibrillation (AF) has been associated with worse outcomes after primary percutaneous coronary intervention (PCI) for acute myocardial infarction. The…”
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Long-Term Outcome of Percutaneous Coronary Intervention for Chronic Total Occlusions
Published in JACC. Cardiovascular interventions (01-09-2011)“…Objectives The aim of this study was to evaluate long-term clinical outcomes after percutaneous coronary intervention (PCI) for chronic total occlusions (CTO)…”
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Effects of Ticagrelor Versus Clopidogrel in Troponin-Negative Patients With Low-Risk ACS Undergoing Ad Hoc PCI
Published in Journal of the American College of Cardiology (16-02-2016)“…Abstract Background Many low-risk acute coronary syndrome (ACS) patients are not pre-treated with a P2Y12 receptor inhibitor, and percutaneous coronary…”
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