Search Results - "Rowntree, C"

Altered microRNA expression in COVID-19 patients enables identification of SARS-CoV-2 infection by Farr, Ryan J, Rootes, Christina L, Rowntree, Louise C, Nguyen, Thi H. O, Hensen, Luca, Kedzierski, Lukasz, Cheng, Allen C, Kedzierska, Katherine, Au, Gough G, Marsh, Glenn A, Vasan, Seshadri S, Foo, Chwan Hong, Cowled, Christopher, Stewart, Cameron R

“…The host response to SARS-CoV-2 infection provide insights into both viral pathogenesis and patient management. The host-encoded microRNA (miRNA) response to…”
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Systems serology detects functionally distinct coronavirus antibody features in children and elderly by Selva, Kevin J., van de Sandt, Carolien E., Lemke, Melissa M., Lee, Christina Y., Shoffner, Suzanne K., Chua, Brendon Y., Davis, Samantha K., Nguyen, Thi H. O., Rowntree, Louise C., Hensen, Luca, Koutsakos, Marios, Wong, Chinn Yi, Mordant, Francesca, Jackson, David C., Flanagan, Katie L., Crowe, Jane, Tosif, Shidan, Neeland, Melanie R., Sutton, Philip, Licciardi, Paul V., Crawford, Nigel W., Cheng, Allen C., Doolan, Denise L., Amanat, Fatima, Krammer, Florian, Chappell, Keith, Modhiran, Naphak, Watterson, Daniel, Young, Paul, Lee, Wen Shi, Wines, Bruce D., Mark Hogarth, P., Esterbauer, Robyn, Kelly, Hannah G., Tan, Hyon-Xhi, Juno, Jennifer A., Wheatley, Adam K., Kent, Stephen J., Arnold, Kelly B., Kedzierska, Katherine, Chung, Amy W.

“…The hallmarks of COVID-19 are higher pathogenicity and mortality in the elderly compared to children. Examining baseline SARS-CoV-2 cross-reactive…”
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Pegylated-asparaginase during induction therapy for adult acute lymphoblastic leukaemia: toxicity data from the UKALL14 trial by Patel, B, Kirkwood, A A, Dey, A, Marks, D I, McMillan, A K, Menne, T F, Micklewright, L, Patrick, P, Purnell, S, Rowntree, C J, Smith, P, Fielding, A K

“…Safety and efficacy data on pegylated asparaginase (PEG-ASP) in adult acute lymphoblastic leukaemia (ALL) induction regimens are limited. The UK National…”
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Mapping the immunopeptidome of seven SARS-CoV-2 antigens across common HLA haplotypes by Braun, Asolina, Rowntree, Louise C., Huang, Ziyi, Pandey, Kirti, Thuesen, Nikolas, Li, Chen, Petersen, Jan, Littler, Dene R., Raji, Shabana, Nguyen, Thi H. O., Jappe Lange, Emma, Persson, Gry, Schantz Klausen, Michael, Kringelum, Jens, Chung, Shanzou, Croft, Nathan P., Faridi, Pouya, Ayala, Rochelle, Rossjohn, Jamie, Illing, Patricia T., Scull, Katherine E., Ramarathinam, Sri, Mifsud, Nicole A., Kedzierska, Katherine, Sørensen, Anders Bundgård, Purcell, Anthony W.

“…Most COVID-19 vaccines elicit immunity against the SARS-CoV-2 Spike protein. However, Spike protein mutations in emerging strains and immune evasion by the…”
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CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age by Menon, Tejas, Illing, Patricia T., Chaurasia, Priyanka, McQuilten, Hayley A., Shepherd, Chloe, Rowntree, Louise C., Petersen, Jan, Littler, Dene R., Khuu, Grace, Huang, Ziyi, Allen, Lilith F., Rockman, Steve, Crowe, Jane, Flanagan, Katie L., Wakim, Linda M., Nguyen, Thi H. O., Mifsud, Nicole A., Rossjohn, Jamie, Purcell, Anthony W., van de Sandt, Carolien E., Kedzierska, Katherine

“…Influenza B viruses (IBVs) cause substantive morbidity and mortality, and yet immunity towards IBVs remains understudied. CD8 + T-cells provide broadly…”
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Immunogenicity and protective efficacy of a co-formulated two-in-one inactivated whole virus particle COVID-19/influenza vaccine by Handabile, Chimuka, Ohno, Marumi, Sekiya, Toshiki, Nomura, Naoki, Kawakita, Tomomi, Kawahara, Mamiko, Endo, Masafumi, Nishimura, Tomohiro, Okumura, Minako, Toba, Shinsuke, Sasaki, Michihito, Orba, Yasuko, Chua, Brendon Y., Rowntree, Louise C., Nguyen, Thi H. O., Shingai, Masashi, Sato, Akihiko, Sawa, Hirofumi, Ogasawara, Kazumasa, Kedzierska, Katherine, Kida, Hiroshi

“…Due to the synchronous circulation of seasonal influenza viruses and severe acute respiratory coronavirus 2 (SARS-CoV-2) which causes coronavirus disease 2019…”
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Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A68:01 allomorph by van de Sandt, C. E., Clemens, E. B., Grant, E. J., Rowntree, L. C., Sant, S., Halim, H., Crowe, J., Cheng, A. C., Kotsimbos, T. C., Richards, M., Miller, A., Tong, S. Y. C., Rossjohn, J., Nguyen, T. H. O., Gras, S., Chen, W., Kedzierska, K.

“…Although influenza viruses lead to severe illness in high-risk populations, host genetic factors associated with severe disease are largely unknown. As the…”
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Soybean Yield Partitioning Changes Revealed by Genetic Gain and Seeding Rate Interactions by Suhre, Justin J., Weidenbenner, Nicholas H., Rowntree, Scott C., Wilson, Eric W., Naeve, Seth L., Conley, Shawn P., Casteel, Shaun N., Diers, Brian W., Esker, Paul D., Specht, James E., Davis, Vince M.

“…Soybean [Glycine max (L.) Merr.] yield has increased during the past century; however, little is understood about the morphological parameters that have…”
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Genetic Gain × Management Interactions in Soybean: I. Planting Date by Rowntree, Scott C., Suhre, Justin J., Weidenbenner, Nicholas H., Wilson, Eric W., Davis, Vince M., Naeve, Seth L., Casteel, Shaun N., Diers, Brian W., Esker, Paul D., Specht, James E., Conley, Shawn P.

“…ABSTRACT Planting date is a commonly manipulated management practice in soybean [Glycine max (L.) Merr.] production; however, the impacts of past and ongoing…”
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T Cell Epitope Discovery in the Context of Distinct and Unique Indigenous HLA Profiles by Hensen, Luca, Illing, Patricia T, Rowntree, Louise C, Davies, Jane, Miller, Adrian, Tong, Steven Y C, Habel, Jennifer R, van de Sandt, Carolien E, Flanagan, Katie L, Purcell, Anthony W, Kedzierska, Katherine, Clemens, E Bridie

“…CD8 T cells are a pivotal part of the immune response to viruses, playing a key role in disease outcome and providing long-lasting immunity to conserved…”
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Immunization with inactivated whole virus particle influenza virus vaccines improves the humoral response landscape in cynomolgus macaques by Chua, Brendon Y, Sekiya, Toshiki, Koutsakos, Marios, Nomura, Naoki, Rowntree, Louise C, Nguyen, Thi H O, McQuilten, Hayley A, Ohno, Marumi, Ohara, Yuki, Nishimura, Tomohiro, Endo, Masafumi, Itoh, Yasushi, Habel, Jennifer R, Selva, Kevin J, Wheatley, Adam K, Wines, Bruce D, Hogarth, P Mark, Kent, Stephen J, Chung, Amy W, Jackson, David C, Brown, Lorena E, Shingai, Masashi, Kedzierska, Katherine, Kida, Hiroshi

“…Although antibody-inducing split virus vaccines (SV) are currently the most effective way to combat seasonal influenza, their efficacy can be modest,…”
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T Cells Targeting SARS-CoV-2: By Infection, Vaccination, and Against Future Variants by Nguyen, Thi H O, Cohen, Carolyn A, Rowntree, Louise C, Bull, Maireid B, Hachim, Asmaa, Kedzierska, Katherine, Valkenburg, Sophie A

“…T cell responses are a key cornerstone to viral immunity to drive high-quality antibody responses, establishing memory for recall and for viral clearance…”
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Physiological and Phenological Responses of Historical Soybean Cultivar Releases to Earlier Planting by Rowntree, Scott C., Suhre, Justin J., Weidenbenner, Nicholas H., Wilson, Eric W., Davis, Vince M., Naeve, Seth L., Casteel, Shaun N., Diers, Brian W., Esker, Paul D., Conley, Shawn P.

“…ABSTRACT The trend toward earlier soybean [Glycine max (L.) Merr.] planting in the midwestern United States has interacted synergistically with genetic yield…”
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High-dose chemotherapy and autologous stem cell transplantation for primary central nervous system lymphoma: a multi-centre retrospective analysis from the United Kingdom by Kassam, S, Chernucha, E, O’Neill, A, Hemmaway, C, Cummins, T, Montoto, S, Lennard, A, Adams, G, Linton, K, McKay, P, Davies, D, Rowntree, C, Easdale, S, Eyre, T A, Marcus, R, Cwynarski, K, Fox, C P

“…The prognosis of patients with primary central nervous system lymphoma (PCNSL) has improved in recent years. This has partly been achieved by remission…”
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Preferential HLA-B27 Allorecognition Displayed by Multiple Cross-Reactive Antiviral CD8 + T Cell Receptors by Rowntree, Louise C, van den Heuvel, Heleen, Sun, Jessica, D'Orsogna, Lloyd J, Nguyen, Thi H O, Claas, Frans H J, Rossjohn, Jamie, Kotsimbos, Tom C, Purcell, Anthony W, Mifsud, Nicole A

“…T cells provide essential immunosurveillance to combat and eliminate infection from pathogens, yet these cells can also induce unwanted immune responses via T…”
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High glycemic variability is associated with a reduced T cell cytokine response to influenza A virus by Tong, Marcus Z.W., Hulme, Katina D., Law, Soi Cheng, Noye, Ellesandra, Dorey, Emily S., Chew, Keng Yih, Rowntree, Louise C., van de Sandt, Carolien E., Kedzierska, Katherine, Goeijenbier, Marco, Ronacher, Katharina, Alzaid, Fawaz, Julla, Jean-Baptiste, Riveline, Jean-Pierre, Lineburg, Katie E., Smith, Corey, Grant, Emma J., Gras, Stephanie, Gallo, Linda A., Barrett, Helen L., Short, Kirsty R.

“…Diabetes mellitus significantly increases the risk of severe respiratory virus disease like influenza and COVID-19. Early evidence suggests that this…”
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Rates of inclusion of teenagers and young adults in England into National Cancer Research Network clinical trials: Report from the National Cancer Research Institute (NCRI) Teenage and Young Adult Clinical Studies Development Group by Fern, L, Davies, S, Eden, T, Feltbower, R, Grant, R, Hawkins, M, Lewis, I, Loucaides, E, Rowntree, C, Stenning, S, Whelan, J

“…Poor inclusion rates into clinical trials for teenagers and young adults (TYA; aged 13–24 years) have been assumed but not systematically investigated in…”
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Robust correlations across six SARS‐CoV‐2 serology assays detecting distinct antibody features by Rowntree, Louise C, Chua, Brendon Y, Nicholson, Suellen, Koutsakos, Marios, Hensen, Luca, Douros, Celia, Selva, Kevin, Mordant, Francesca L, Wong, Chinn Yi, Habel, Jennifer R, Zhang, Wuji, Jia, Xiaoxiao, Allen, Lily, Doolan, Denise L, Jackson, David C, Wheatley, Adam K, Kent, Stephen J, Amanat, Fatima, Krammer, Florian, Subbarao, Kanta, Cheng, Allen C, Chung, Amy W, Catton, Mike, Nguyen, Thi HO, Sandt, Carolien E, Kedzierska, Katherine

“…Objectives As the world transitions into a new era of the COVID‐19 pandemic in which vaccines become available, there is an increasing demand for rapid…”
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Prospective comprehensive profiling of immune responses to COVID‐19 vaccination in patients on zanubrutinib therapy by Nguyen, Thi H. O., Lim, Chhay, Lasica, Masa, Whitechurch, Ashley, Tennakoon, Surekha, Saunders, Natalie R., Allen, Lilith F., Rowntree, Louise C., Chua, Brendon Y., Kedzierski, Lukasz, Tan, Hyon‐Xhi, Wheatley, Adam K., Kent, Stephen J., Karapanagiotidis, Theo, Nicholson, Suellen, Williamson, Deborah A., Slavin, Monica A., Tam, Constantine S., Kedzierska, Katherine, Teh, Benjamin W.

“…Zanubrutinib‐treated and treatment‐naïve patients with chronic lymphocytic leukaemia (CLL) or Waldenstrom's macroglobulinaemia were recruited in this…”
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Robust immunity to influenza vaccination in haematopoietic stem cell transplant recipients following reconstitution of humoral and adaptive immunity by Zhang, Wuji, Rowntree, Louise C, Muttucumaru, Ramona, Damelang, Timon, Aban, Malet, Hurt, Aeron C, Auladell, Maria, Esterbauer, Robyn, Wines, Bruce, Hogarth, Mark, Turner, Stephen J, Wheatley, Adam K, Kent, Stephen J, Patil, Sushrut, Avery, Sharon, Morrissey, Orla, Chung, Amy W, Koutsakos, Marios, Nguyen, Thi HO, Cheng, Allen C, Kotsimbos, Tom C, Kedzierska, Katherine

“…Objectives Influenza causes significant morbidity and mortality, especially in high‐risk populations. Although current vaccination regimens are the best method…”
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