Search Results - "Rowley, M.J."

Latent autoimmune diabetes mellitus in adults (LADA): the role of antibodies to glutamic acid decarboxylase in diagnosis and prediction of insulin dependency by Zimmet, P Z, Tuomi, T, Mackay, I R, Rowley, M J, Knowles, W, Cohen, M, Lang, D A

“…Type 1 diabetes mellitus in adults may present in a manner similar to that of Type 2 diabetes but with a late development of insulin dependency. We studied 65…”
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Comparative expression and purification of human glutamic acid decarboxylase from Saccharomyces cerevisiae and Pichia pastoris by Papakonstantinou, T., Law, R.H.P., Gardiner, P., Rowley, M.J., Mackay, I.R.

“…The yeast cell factory is a potentially useful source of proteins in general. They include glutamic acid decarboxylase (GAD), which is one of the major…”
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Autoantibodies to glutamic acid decarboxylase and insulin in islet cell antibody positive presymptomatic type 1 diabetes mellitus: frequency and segregation by age and gender by Zimmet, P Z, Elliott, R B, Mackay, I R, Tuomi, T, Rowley, M J, Pilcher, C C, Knowles, W J

“…The frequency of antibodies to glutamic acid decarboxylase (GAD) and insulin (IAA) in presymptomatic Type 1 diabetes mellitus with a positive test for…”
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Antibodies to diabetes-associated autoantigens in Indian patients with Type 1 diabetes: prevalence of anti-ICA512/IA2 and anti-SOX13 by Fida, S, Myers, M, Mackay, I.R, Zimmet, P.Z, Mohan, V, Deepa, R, Rowley, M.J

“…We ascertained frequencies of autoantibodies to a suite of islet cell antigens including ICA512/IA2 and SOX13 in Asian Indians with Type 1 diabetes and in…”
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Characterization of Epitopes for Virus-Neutralizing Monoclonal Antibodies to Ross River Virus E2 Using Phage-Displayed Random Peptide Libraries by Davies, J.M., Cai, Y.-P., Weir, R.C., Rowley, M.J.

“…Ross River virus (RRV) is the predominant cause of epidemic polyarthritis in Australia, yet the antigenic determinants are not well defined. We aimed to…”
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Autoantibodies to glutamic acid decarboxylase and phenotypic features associated with early insulin treatment in individuals with adult-onset diabetes mellitus by Humphrey, A.R.G., McCarty, D.J., Mackay, I.R., Rowley, M.J., Dwyer, T., Zimmet, P.

“…We investigated the association of serum antibodies to glutamic acid decarboxylase (GADab) with early start of insulin treatment (≤ 1 year from diagnosis, or ≤…”
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Antibody Reactivity to Mycobacterial 65kDa Heat Shock Protein: Relevance to Autoimmunity by Karopoulos, C., Rowley, M.J., Handley, C.J., Strugnell, R.A.

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Autoantibodies associated with presymptomatic insulin-dependent diabetes mellitus in women by Whittingham, S., Byron, S.L., Tuomilehto, J., Zimmet, P.Z., Myers, M.A., Vidgren, G., Rowley, M.J., Feeney, S.J., Koskela, P., Tuomilehto-Wolf, E., Mackay, I.R.

“…Presymptomatic autoantibody markers of insulin‐dependent (Type 1) diabetes mellitus (IDDM) are less well characterized in adults than in children. We…”
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Pancreatic β cell function and antibodies to glutamic acid decarboxylase (anti-GAD) in Chinese patients with clinical diagnosis of insulin-dependent diabetes mellitus by Chan, J.C.N., Yeung, V.T.F., Chow, C.C., Ko, G.T.C., Mackay, I.R., Rowley, M.J., Zimmet, P.Z., Cockram, C.S.

“…Antibodies to glutamic acid decarboxylase (anti-GAD) and pancreatic β cell secretory function were measured in 39 consecutive Chinese patients with a clinical…”
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Antibody Reactivity to Mycobacterial 65 kDa Heat Shock Protein: Relevance to Autoimmunity by Karopoulos, C., Rowley, M.J., Handley, C.J., Strugnell, R.A.

“…Reactivity to the mycobacterial 65kDa heat shock protein (HSP 65) has been implicated in the pathogenesis of adjuvant arthritis in the rat, and may be involved…”
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Antibodies to ICA512/IA-2 in Rodent Models of IDDM by Myers, M.A, Laks, M.R, Feeney, S.J, Mandel, T.E, Koulmanda, M, Bone, A, Barley, J, Rowley, M.J, Mackay, I.R

“…Antibodies to ICA512/IA-2 are a well established marker of human IDDM and can be detected prior to and soon after the onset of insulin dependency. The…”
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Autoantigenic Reactivity of Diabetes Sera with a Hybrid Glutamic Acid Decarboxylase GAD67-65 Molecule GAD67(1-101)/GAD65(96-585) by Teoh, K. L., Fida, S., Rowley, M.J., Mackay, I. R.

“…Glutamic acid decarboxylase (GAD) is a major autoantigen in insulin-dependent diabetes mellitus (IDDM). Two GAD isoforms exist, GAD65 and GAD67, which differ…”
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Immunosusceptibility genes in rheumatoid arthritis by Sherritt, M.A., Tait, B., Varney, M., Kanaan, C., Stockman, A., Mackay, I.R., Muirden, K., Bernard, C.C.A., Rowley, M.J.

“…The polygenic predisposition to RA is conferred particularly by disease susceptibility sequences in the HVR3 of HLA DRB1 present in those subtypes of DR4 and…”
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Lack of Autoimmune Serological Reactions in Rodent Models of Insulin Dependent Diabetes Mellitus by Mackay, I.R., Bone, A., Tuomi, T., Elliott, R., Mandel, T., Karopoulos, C., Rowley, M.J.

“…Spontaneous insulitis with insulin-dependent diabetes mellitus (IDDM) in rodent models, the BB rat and NOD mouse, has clarified the pathogenesis of and guided…”
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Effect of Graded Doses of Ionizing Radiation on the Human Testis by Rowley, Mavis J., Leach, David R., Warner, Glenn A., Heller, Carl G.

“…A portable unit was developed to provide uniform irradiation of the human testes. The device had built-in radiological protection and provided a dosage…”
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Autoreactive MHC-restricted cytotoxic cells in BALB/c mice after novel immunisation with a conserved mammalian autoantigen by Karanikas, V, Mackay, I R, Rowley, M J, Loveland, B E

“…We investigated whether a novel immunisation scheme using an endogenous protein could stimulate an autoreactive cytolytic response. The protein selected was…”
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Book review: Power Generation and the Environment by Cowherd, S.J., Rowley, M.J.

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Bone trauma and related benign disease: assessment by bone scanning by Marty, R, Denney, J D, McKamey, M R, Rowley, M J

“…The radionuclide investigation of skeletal trauma in the past was confined generally to scintimetry and an occasional bone scan. The development of improved…”
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Differing Frequency of Autoantibodies to Glutamic Acid Decarboxylase among Koreans, Thais, and Australians with Diabetes Mellitus by Tuomi, T., Zimmet, P., Rowley, M.J., Min, H.K., Vichayanrat, A., Lee, H.K., Rhee, B.D., Vannasaeng, S., Humphrey, A.R.G., Mackay, I.R.

“…The wide racial-geographic differences in the incidence and prevalence of insulin-dependent diabetes mellitus (IDDM) between Europids and Asian populations…”
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Subclasses of immunoglobulins and autoantibodies in autoimmune diseases by Outschoorn, I, Rowley, M J, Cook, A D, Mackay, I R

“…The differing capacity of subclasses of IgG to bind to protein A and protein G was used in a sequential affinity purification procedure to examine…”
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