Search Results - "Rowley, J.A"

Increasing yield of msc-evs in scalable xeno-free manufacturing by Adlerz, K, Trempel, M, Rowley, J.A, Ahsan, T

“…Background & AimExtracellular vesicles (EVs) are increasingly being investigated as both drug delivery vehicles and as a cell-free therapy. EVs from…”
Get full text

A Xeno-free fed-batch microcarrier suspension bioreactor system for the scalable and economic expansion of hBM-MSCs by Olsen, T.R, Kirian, R, Lock, L, Rowley, J.A

Get full text

Rapid and robust large-scale expansion of high quality human mesenchymal stem cells for use in regenerative medicine applications by Splan, D, Lock, L, Rowley, J.A, Szczypka, M.S

Get full text

A fed-batch microcarrier suspension bioreactor system for the scalable expansion of hBM-MSCs by Olsen, T.R, Lock, L, Dailey, K, Rowley, J.A

Get full text

Functional & economic comparability of Xeno-free stem cell bioprocess system by Lock, L, Dailey, K, Rowley, J.A

Get full text

Successful technology transfer of a cgmp potency assay for an ancillary material to support cgmp stem cell manufacturing by Adlerz, K, Takacs, J, Lock, L, Ahsan, T, Rowley, J.A

Get full text

Comparison of msc-evs manufatured in 2D versus scalable 3D bioreactor systems by Adlerz, K, Trempel, M, Wang, D, Kirian, R.D, Rowley, J.A, Ahsan, T

“…Background & AimThere have been over 800 registered clinical trials using mesenchymal stem/stromal cells (MSCs) for therapeutic applications. Due to their…”
Get full text

The effect of cryomedia selection and transient warming events on post-cryopreservation human MSC function by Hawkins, B.J, Abazari, A, Lock, L, Ahsan, T, Rowley, J.A, Fink, J, Mathew, A

Get full text

Scaling a xeno-free fed-batch microcarrier suspension bioreactor system from development to production scale for manufacturing XF hMSCs by Kirian, R.D, Wang, D, Takacs, J, Tsai, A, Cruz, K, Rosello, F, Cox, K, Hashimura, Y, Lembong, J, Rowley, J.A, Jung, S, Ahsan, T

“…Background & AimWith over 800 clinical trials investigating the use of mesenchymal stem/stromal cells (hMSCs) for regenerative medicine, there is an urgent…”
Get full text

A FED-BATCH CHEMICALLY DEFINED HMSC-EV BIOPROCESS MEDIUM ENABLING 2-4X EV YIELD IMPROVEMENTS IN BIOREACTOR CULTURE by Willstaedt, T.M., Walde, A., Rowley, J.A.

“…Extracellular vesicles (EVs) derived from human mesenchymal stromal cells (hMSC-EVs) have been studied in over 200 preclinical applications and dozens of human…”
Get full text

Mesenchymal Stem/Stromal Cells: OPTIMIZATION OF TRANSIENT TRANSFECTION OF MESENCHYMAL STROMAL CELLS WITH PLASMID DNA OR MESSENGER RNA by Doolin, M.T., Willstaedt, T.M., Rowley, J.A.

Get full text

A COMPARABILITY STUDY OF CHROMATOGRAPHY RESINS SUITABLE FOR EV PURIFICATION FROM A HIGHLY PRODUCTIVE MSC BIOPROCESSING PLATFORM by Jung, J., Lenzini, S., Budiman, M., Rowley, J.A., Zakhem, E.

“…Background & Aim: The number of clinical trials investigating extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) as a therapeutic agent…”
Get full text

SCALABLE GMP-COMPATIBLE PROCESS SOLUTION FOR MSC-EV PURIFICATION WITH 10X YIELD IMPROVEMENTS by Lenzini, S., Jung, J., Cramer, M., Zakhem, E., Rowley, J.A.

“…Clinical trials investigating extracellular vesicles (EVs) from mesenchymal stromal cells (MSCs) have rapidly increased in recent years. Scalable…”
Get full text

Enhancing hMSC extracellular vesicle productivity with a novel collection media for scalable MSC-EV generation by Trempel, M., Adlerz, K., Rowley, J.A.

Get full text

Gene Editing/Gene Therapies: A GMP-COMPATIBLE PROCESS FOR THE EFFICIENT TRANSFECTION OF MSCS WITH mRNA by Doolin, M.T., Willstaedt, T.M., Boychyn, M., Rowley, J.A.

Get full text

1235 - Gene Editing/Gene Therapies: A GMP-COMPATIBLE PROCESS FOR THE EFFICIENT TRANSFECTION OF MSCS WITH mRNA by Doolin, M.T., Willstaedt, T.M., Boychyn, M., Rowley, J.A.

Get full text

Mesenchymal Stem/Stromal Cells: DEVELOPMENT OF AN OPTIMIZED LENTIVIRAL TRANSDUCTION MEDIUM AND PROCESS TO MANUFACTURE GENETICALLY MODIFIED MSC WORKING CELL BANKS by Willstaedt, T.M., Walde, A., Brennan, J., Rowley, J.A., Adlerz, K.

Get full text

Development of an optimized lentiviral transduction medium and process to manufacture genetically modified MSC working cell banks by Willstaedt, T.M., Walde, A., Brennan, J., Rowley, J.A., Adlerz, K.

Get full text

Scalable manufacturing system for MSC-EV generation by Adlerz, K., Lembong, J., Patel, D., Rowley, J.A., Ahsan, T.

“…Due to their potential as a key bioactive agent in regenerative medicine applications, MSC-derived extracellular vesicles (MSC-EVs) are increasingly being…”
Get full text

Exosomes/EVs: DEVELOPING A MICROCARRIER STIRRED TANK PROCESS FOR LARGE-SCALE HMSC-EV PRODUCTION by Lenzini, S., Jung, J., Kirian, R., Brennan, J., Zakhem, E., Rowley, J.A.

Get full text