Search Results - "Rowles, Alison"

Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs by Sokal, David M, McSloy, Alex, Donegà, Matteo, Kirk, Joseph, Colas, Romain A, Dolezalova, Nikola, Gomez, Esteban A, Gupta, Isha, Fjordbakk, Cathrine T, Ouchouche, Sebastien, Matteucci, Paul B, Schlegel, Kristina, Bashirullah, Rizwan, Werling, Dirk, Harman, Kim, Rowles, Alison, Yazicioglu, Refet Firat, Dalli, Jesmond, Chew, Daniel J, Perkins, Justin D

“…Neuromodulation of the immune system has been proposed as a novel therapeutic strategy for the treatment of inflammatory conditions. We recently demonstrated…”
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Keratinocyte Differentiation Is Regulated by the Rho and ROCK Signaling Pathway by McMullan, Rachel, Lax, Siân, Robertson, Vicki H., Radford, David J., Broad, Simon, Watt, Fiona M., Rowles, Alison, Croft, Daniel R., Olson, Michael F., Hotchin, Neil A.

“…The epidermis comprises multiple layers of specialized epithelial cells called keratinocytes. As cells are lost from the outermost epidermal layers, they are…”
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The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin by Romanowski, Piotr, Madine, Mark A., Rowles, Alison, Blow, J.Julian, Laskey, Ronald A.

“…Background The origin recognition complex (ORC) and the minichromosome maintenance (MCM) protein complex were initially discovered in yeast and shown to be…”
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Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response by Gray, Carol W., Ward, Robin V., Karran, Eric, Turconi, Sandra, Rowles, Alison, Viglienghi, Daniela, Southan, Christopher, Barton, Amanda, Fantom, Kenneth G., West, Andrew, Savopoulos, John, Hassan, Namir J., Clinkenbeard, Helen, Hanning, Charles, Amegadzie, Bernard, Davis, John B., Dingwall, Colin, Livi, George P., Creasy, Caretha L.

“…Human HtrA2 is a novel member of the HtrA serine protease family and shows extensive homology to the Escherichia coli HtrA genes that are essential for…”
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Characterization of the Xenopus replication licensing system by Chong, J P, Thömmes, P, Rowles, A, Mahbubani, H M, Blow, J J

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A self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models by Maruggi, Giulietta, Mallett, Corey P., Westerbeck, Jason W., Chen, Tiffany, Lofano, Giuseppe, Friedrich, Kristian, Qu, Lin, Sun, Jennifer Tong, McAuliffe, Josie, Kanitkar, Amey, Arrildt, Kathryn T., Wang, Kai-Fen, McBee, Ian, McCoy, Deborah, Terry, Rebecca, Rowles, Alison, Abrahim, Maia Araujo, Ringenberg, Michael A., Gains, Malcolm J., Spickler, Catherine, Xie, Xuping, Zou, Jing, Shi, Pei-Yong, Dutt, Taru, Henao-Tamayo, Marcela, Ragan, Izabela, Bowen, Richard A., Johnson, Russell, Nuti, Sandra, Luisi, Kate, Ulmer, Jeffrey B., Steff, Ann-Muriel, Jalah, Rashmi, Bertholet, Sylvie, Stokes, Alan H., Yu, Dong

“…RNA vaccines have demonstrated efficacy against SARS-CoV-2 in humans, and the technology is being leveraged for rapid emergency response. In this report, we…”
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Human-relevant near-organ neuromodulation of the immune system via the splenic nerve by Donegà, Matteo, Fjordbakk, Cathrine T., Kirk, Joseph, Sokal, David M., Gupta, Isha, Hunsberger, Gerald E., Crawford, Abbe, Cook, Simon, Viscasillas, Jaime, Stathopoulou, Thaleia-Rengina, Miranda, Jason A., Dopson, Wesley J., Goodwin, David, Rowles, Alison, McGill, Paul, McSloy, Alex, Werling, Dirk, Witherington, Jason, Chew, Daniel J., Perkins, Justin D.

“…Neuromodulation of immune function by stimulating the autonomic connections to the spleen has been demonstrated in rodent models. Consequently, neuroimmune…”
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Evaluation of Nonacog Beta Pegol Long-term Safety in the Immune-deficient Rowett Nude Rat (Crl:NIH-Foxn1rnu) by Rasmussen, Caroline E., Nowak, Jette, Larsen, Julie M., Bottomley, Anna, Rowles, Alison, Offenberg, Hanne

“…Nonacog beta pegol is a 40-kDa polyethylene glycosylated (PEGylated) human recombinant coagulation factor IX, intended for the treatment of hemophilia B. Human…”
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Myelin-associated Glycoprotein Interacts with Ganglioside GT1b by Vinson, Mary, Strijbos, Paul J.L.M., Rowles, Alison, Facci, Laura, Moore, Stephen E., Simmons, David L., Walsh, Frank S.

“…Myelin-associated glycoprotein (MAG) is expressed on myelinating glia and inhibits neurite outgrowth from post-natal neurons. MAG has a sialic acid binding…”
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Receptor-interacting protein 1 kinase inhibition therapeutically ameliorates experimental T cell-dependent colitis in mice by Gobbetti, Thomas, Berger, Scott B., Fountain, Kathryn, Slocombe, Tom, Rowles, Alison, Pearse, Gail, Harada, Isobel, Bertin, John, Haynes, Andrea C., Beal, Allison M.

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Detection of Mild and Reversible Neurohistopathological Changes in the Brain of Juvenile (Preweaned) Beagle Dogs Treated with Vigabatrin for up to 91 Days by Bottomley, Anna L., Rowles, Alison, Mitchell, David J., Rasmussen, Allan D.

“…Neurohistopathological changes in the brain were assessed in juvenile beagle dogs given vigabatrin at 30 or 100 mg/kg/day by oral gavage from postnatal day 22…”
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Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves by Gupta, Isha, Cassará, Antonino M., Tarotin, Ilya, Donega, Matteo, Miranda, Jason A., Sokal, David M., Ouchouche, Sebastien, Dopson, Wesley, Matteucci, Paul, Neufeld, Esra, Schiefer, Matthew A., Rowles, Alison, McGill, Paul, Perkins, Justin, Dolezalova, Nikola, Saeb-Parsy, Kourosh, Kuster, Niels, Yazicioglu, Refet Firat, Witherington, Jason, Chew, Daniel J.

“…Neuromodulation is a new therapeutic pathway to treat inflammatory conditions by modulating the electrical signalling pattern of the autonomic connections to…”
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Interaction between the Origin Recognition Complex and the Replication Licensing Systemin Xenopus by Rowles, Alison, Chong, James P.J, Brown, Lamorna, Howell, Mike, Evan, Gerard I, Blow, J.Julian

“…The origin recognition complex (ORC) binds to origins of replication in budding yeast. We have cloned a Xenopus homolog of the largest ORC polypeptide (XORC1)…”
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Changes in association of the Xenopus origin recognition complex with chromatin on licensing of replication origins by Rowles, A, Tada, S, Blow, J J

“…During late mitosis and early G1, a series of proteins are assembled onto replication origins that results in them becoming 'licensed' for replication in the…”
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Myelin-associated glycoprotein interacts with ganglioside GT1b. A mechanism for neurite outgrowth inhibition by Vinson, M, Strijbos, P J, Rowles, A, Facci, L, Moore, S E, Simmons, D L, Walsh, F S

“…Myelin-associated glycoprotein (MAG) is expressed on myelinating glia and inhibits neurite outgrowth from post-natal neurons. MAG has a sialic acid binding…”
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Interaction between the origin recognition complex and the replication licensing system in Xenopus by Rowles, A, Chong, J P, Brown, L, Howell, M, Evan, G I, Blow, J J

“…The origin recognition complex (ORC) binds to origins of replication in budding yeast. We have cloned a Xenopus homolog of the largest ORC polypeptide (XORC1)…”
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Interaction of Xenopus Cdc2·Cyclin A1 with the Origin Recognition Complex by Romanowski, Piotr, Marr, Jackie, Madine, Mark A., Rowles, Alison, Blow, J.Julian, Gautier, Jean, Laskey, Ronald A.

“…The initiation of DNA replication in eukaryotes is regulated in a minimum of at least two ways. First, several proteins, including origin recognition complex…”
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Chromatin proteins involved in the initiation of DNA replication by Rowles, Alison, Blow, J Julian

“…Eukaryotic DNA replication is regulated at least in part by the assembly of initiation proteins onto origins of replication. The origin recognition complex…”
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Interaction of Xenopus Cdc2·Cyclin A1 with the Origin Recognition Complex by Piotr Romanowski, Jackie Marr, Mark A. Madine, Alison Rowles, J. Julian Blow, Jean Gautier, Ronald A. Laskey

“…The initiation of DNA replication in eukaryotes is regulated in a minimum of at least two ways. First, several proteins, including origin recognition complex…”
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