Search Results - "Rowland, Caroline A."

In vivo manipulation of γ9(+) T cells in the common marmoset (Callithrix Jacchus) with phosphoantigen and effect on the progression of respiratory melioidosis by Laws, Thomas R, Nelson, Michelle, Bonnafous, Cecile, Sicard, Helene, Taylor, Christopher, Salguero, Francisco Javier, Atkins, Timothy P, Oyston, Petra C F, Rowland, Caroline A

“…Burkholderia pseudomallei is a dangerous human pathogen. Phosphoantigens specifically the target primate specific γ9(+)δ2(+) T cells subset and some have been…”
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Vaccines and Therapies for Biodefence Agents by Tree, Julia A., Williamson, E. Diane, Rowland, Caroline A., Pitt, Louise M.

“…Biothreat agents usually cause severe disease so clinical efficacy studies of candidate vaccines or therapies will generally not be ethical or feasible, unless…”
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The Impact of “Omic” and Imaging Technologies on Assessing the Host Immune Response to Biodefence Agents by Rowland, Caroline A., Elmore, Michael J., Flick-Smith, Helen, Tree, Julia A.

“…Understanding the interactions between host and pathogen is important for the development and assessment of medical countermeasures to infectious agents,…”
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Development of microflow ultra high performance liquid chromatography-mass spectrometry metabolomic assays for analysis of mammalian biofluids by Harwood-Stamper, Annie J., Rowland, Caroline A., Dunn, Warwick B.

“…Introduction and objectives The application of untargeted metabolomics assays using ultra high performance liquid chromatography-mass spectrometry (UHPLC-MS)…”
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Control of Intracellular Francisella tularensis by Different Cell Types and the Role of Nitric Oxide by Williamson, Diane, Rowland, Caroline A., Hartley, M. Gillian, Gates, Amanda J., Newstead, Sarah L., Lukaszewski, Roman A.

“…Reactive nitrogen is critical for the clearance of Francisella tularensis infections. Here we assess the role of nitric oxide in control of intracellular…”
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Critical Role of Type 1 Cytokines in Controlling Initial Infection with Burkholderia mallei by Rowland, Caroline A, Lertmemongkolchai, Ganjana, Bancroft, Alison, Haque, Ashraful, Lever, M. Stephen, Griffin, Kate F, Jackson, Matthew C, Nelson, Michelle, O'Garra, Anne, Grencis, Richard, Bancroft, Gregory J, Lukaszewski, Roman A

“…Burkholderia mallei is a gram-negative bacterium which causes the potentially fatal disease glanders in humans; however, there is little information concerning…”
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Antibiotic-Loaded Polymersomes for Clearance of Intracellular Burkholderia thailandensis by Porges, Eleanor, Jenner, Dominic, Taylor, Adam W, Harrison, James S P, De Grazia, Antonio, Hailes, Alethia R, Wright, Kimberley M, Whelan, Adam O, Norville, Isobel H, Prior, Joann L, Mahajan, Sumeet, Rowland, Caroline A, Newman, Tracey A, Evans, Nicholas D

“…Melioidosis caused by the facultative intracellular pathogen is difficult to treat due to poor intracellular bioavailability of antibiotics and antibiotic…”
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Using multispectral imaging flow cytometry to assess an in vitro intracellular Burkholderia thailandensis infection model by Jenner, Dominic, Ducker, Catherine, Clark, Graeme, Prior, Jo, Rowland, Caroline A.

“…The use of in vitro models to understand the interaction of bacteria with host cells is well established. In vitro bacterial infection models are often used to…”
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PEGylated liposomes associate with Wnt3A protein and expand putative stem cells in human bone marrow populations by Janeczek, Agnieszka A, Scarpa, Edoardo, Horrocks, Mathew H, Tare, Rahul S, Rowland, Caroline A, Jenner, Dominic, Newman, Tracey A, Oreffo, Richard OC, Lee, Steven F, Evans, Nicholas D

“…To fabricate PEGylated liposomes which preserve the activity of hydrophobic Wnt3A protein, and to demonstrate their efficacy in promoting expansion of…”
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Transient Canonical Wnt Stimulation Enriches Human Bone Marrow Mononuclear Cell Isolates for Osteoprogenitors by Janeczek, Agnieszka A., Tare, Rahul S., Scarpa, Edoardo, Moreno‐Jimenez, Ines, Rowland, Caroline A., Jenner, Dominic, Newman, Tracey A., Oreffo, Richard O. C., Evans, Nicholas D.

“…Activation of the canonical Wnt signaling pathway is an attractive anabolic therapeutic strategy for bone. Emerging data suggest that activation of the Wnt…”
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An assessment of common marmoset (Callithrix jacchus) γ9+ T cells and their response to phosphoantigen in vitro by Rowland, Caroline A., Laws, Thomas R., Oyston, Petra C.F.

“…► Marmoset γ9 T cells are distributed throughout the tissues. ► Marmoset γ9 T cells and human γ9δ2 T cell responses to phosphoantigen are comparable. ► γ9δ2 T…”
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An assessment of common marmoset (Callithrix jacchus) gamma 9+ T cells and their response to phosphoantigen in vitro by Rowland, Caroline A, Laws, Thomas R, Oyston, Petra CF

“…gamma 9 delta 2 T cells are a primate-specific gamma delta T cell subtype that expand and become activated during infection, responding directly to…”
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Peripheral human γδ T cells control growth of both avirulent and highly virulent strains of Francisella tularensis in vitro by Rowland, Caroline A., Hartley, M. Gill, Flick-Smith, Helen, Laws, Thomas R., Eyles, Jim E., Oyston, Petra C.F.

“…In this paper we evaluate the role of human γδ T cells in control of Francisella tularensis infection. Using an in vitro model of infection, a reduction in…”
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Protective cellular responses to Burkholderia mallei infection by Rowland, Caroline A., Lever, M. Stephen, Griffin, Kate F., Bancroft, Gregory J., Lukaszewski, Roman A.

“…Burkholderia mallei is a Gram-negative bacillus causing the disease glanders in humans. During intraperitoneal infection, BALB/c mice develop a chronic disease…”
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The electrostability and electrically assisted delivery of an organophosphate pretreatment (physostigmine) across human skin in vitro by Rowland, Caroline A, Chilcott, Robert P

“…Physostigmine is a tertiary carbamate that is utilised as a pretreatment against organophosphate intoxication. Oral delivery of physostigmine is not practical…”
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Peripheral human I3I' T cells control growth of both avirulent and highly virulent strains of Francisella tularensis in vitro by Rowland, Caroline A, Hartley, MGill, Flick-Smith, Helen, Laws, Thomas R, Eyles, Jim E, Oyston, Petra CF

“…In this paper we evaluate the role of human I3I' T cells in control of Francisella tularensis infection. Using an in vitro model of infection, a reduction in…”
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In Vivo Manipulation of gamma 9+ T Cells in the Common Marmoset (Callithrix Jacchus) with Phosphoantigen and Effect on the Progression of Respiratory Melioidosis: e74789 by Laws, Thomas R, Nelson, Michelle, Bonnafous, Cecile, Sicard, Helene, Taylor, Christopher, Salguero, Francisco Javier, Atkins, Timothy P, Oyston, Petra CF, Rowland, Caroline A

“…Burkholderia pseudomallei is a dangerous human pathogen. Phosphoantigens specifically the target primate specific gamma 9+ delta 2+ T cells subset and some…”
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Characterisation of host immune responses to Burkholderia mallei by Rowland, Caroline A

“…Burkholderia mallei is an intracellular, gram-negative bacterium which causes the disease Glanders in humans and mice. Little research has been performed to…”
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