Search Results - "Rowlan, Jessica"

Insight from OPN1LW Gene Haplotypes into the Cause and Prevention of Myopia by Neitz, Maureen, Wagner-Schuman, Melissa, Rowlan, Jessica S, Kuchenbecker, James A, Neitz, Jay

“…Nearsightedness (myopia) is a global health problem of staggering proportions that has driven the hunt for environmental and genetic risk factors in hopes of…”
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Gene therapy rescues cone function in congenital achromatopsia by Komáromy, András M., Alexander, John J., Rowlan, Jessica S., Garcia, Monique M., Chiodo, Vince A., Kaya, Asli, Tanaka, Jacqueline C., Acland, Gregory M., Hauswirth, William W., Aguirre, Gustavo D.

“…The successful restoration of visual function with recombinant adeno-associated virus (rAAV)-mediated gene replacement therapy in animals and humans with an…”
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Transient Photoreceptor Deconstruction by CNTF Enhances rAAV-Mediated Cone Functional Rescue in Late Stage CNGB3-Achromatopsia by Komáromy, András M, Rowlan, Jessica S, Corr, Amanda T Parton, Reinstein, Shelby L, Boye, Sanford L, Cooper, Ann E, Gonzalez, Amaliris, Levy, Britt, Wen, Rong, Hauswirth, William W, Beltran, William A, Aguirre, Gustavo D

“…Achromatopsia is a genetic disorder of cones, and one of the most common forms is a channelopathy caused by mutations in the β-subunit, CNGB3, of the cone…”
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A novel form of progressive retinal atrophy in Swedish vallhund dogs by Cooper, Ann E, Ahonen, Saija, Rowlan, Jessica S, Duncan, Alison, Seppälä, Eija H, Vanhapelto, Päivi, Lohi, Hannes, Komáromy, András M

“…Inherited retinal degenerations, such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD), represent leading causes of incurable blindness…”
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New quantitative trait loci for carotid atherosclerosis identified in an intercross derived from apolipoprotein E-deficient mouse strains by Rowlan, Jessica S, Zhang, Zhimin, Wang, Qian, Fang, Yan, Shi, Weibin

“…Carotid atherosclerosis is the primary cause of ischemic stroke. To identify genetic factors contributing to carotid atherosclerosis, we performed quantitative…”
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Role of a Dual Splicing and Amino Acid Code in Myopia, Cone Dysfunction and Cone Dystrophy Associated with L / M Opsin Interchange Mutations by Greenwald, Scott H, Kuchenbecker, James A, Rowlan, Jessica S, Neitz, Jay, Neitz, Maureen

“…Human long ( ) and middle ( ) wavelength cone opsin genes are highly variable due to intermixing. Two / cone opsin interchange mutants, designated and , are…”
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Atherosclerosis Susceptibility Loci Identified in an Extremely Atherosclerosis‐Resistant Mouse Strain by Rowlan, Jessica S., Li, Qiongzhen, Manichaikul, Ani, Wang, Qian, Matsumoto, Alan H., Shi, Weibin

“…Background C3H/HeJ (C3H) mice are extremely resistant to atherosclerosis, especially males. To understand the underlying genetic basis, we performed…”
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Genetic Analysis of Atherosclerosis and Glucose Homeostasis in an Intercross Between C57BL/6 and BALB/cJ Apolipoprotein E–Deficient Mice by Zhang, Zhimin, Rowlan, Jessica S, Wang, Qian, Shi, Weibin

“…BACKGROUND—Diabetic patients have an increased risk of developing atherosclerosis and related complications compared with nondiabetic individuals. The…”
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Quantitative Trait Locus Analysis of Neointimal Formation in an Intercross Between C57BL/6 and C3H/HeJ Apolipoprotein E-Deficient Mice by Yuan, Zuobiao, Pei, Hong, Roberts, Drew J, Zhang, Zhimin, Rowlan, Jessica S, Matsumoto, Alan H, Shi, Weibin

“…Quantitative Trait Locus Analysis of Neointimal Formation in an Intercross Between C57BL/6 and C3H/HeJ Apolipoprotein E–Deficient Mice Zuobiao Yuan, MD, PhD ;…”
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Equine Multiple Congenital Ocular Anomalies (MCOA) syndrome in PMEL17 (Silver) mutant ponies: five cases by Komáromy, András M., Rowlan, Jessica S., La Croix, Noelle C., Mangan, Brendan G.

“…Objective  To describe the clinical phenotype and genetics of equine Multiple Congenital Ocular Anomalies (MCOA) syndrome in PMEL17 (Silver) mutant ponies…”
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Quantitative trait locus analysis of circulating adhesion molecules in hyperlipidemic apolipoprotein E-deficient mice by Yuan, Zuobiao, Su, Zhiguang, Miyoshi, Toru, Rowlan, Jessica S, Shi, Weibin

“…Circulating soluble adhesion molecules have been suggested as useful markers to predict several clinical conditions such as atherosclerosis, type 2 diabetes,…”
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Gene therapy rescues cone function in congenital achromatopsia by Komáromy, András M., Alexander, John J., Rowlan, Jessica S., Garcia, Monique M., Chiodo, Vince A., Kaya, Asli, Tanaka, Jacqueline C., Acland, Gregory M., Hauswirth, William W., Aguirre, Gustavo D.

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Characterization of Gene Therapy Associated Uveitis Following Intravitreal Adeno-Associated Virus Injection in Mice by Tummala, Gayathri, Crain, Adam, Rowlan, Jessica, Pepple, Kathryn L

“…To characterize the intraocular immune cell infiltrate induced by intravitreal adeno-associated virus (AAV) gene therapy. AAV vectors carrying plasmids…”
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Poster Session II: Intravitreal gene therapy in primate reaches extrafoveal cones by Bembry-Colegrove, Briyana, Giarmarco, Michelle, Barborek, Rachel, Rowlan, Jessica, Kuchenbecker, James, Rezeanu, Dragos, Neitz, Jay, Neitz, Maureen

“…Intravitreal delivery of gene therapy vectors to the retina carries lower risk of adverse events versus subretinal injections, but efficiently targeting cones…”
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CFH Haploinsufficiency and Complement Alterations in Early-Onset Macular Degeneration by Lim, Rayne R, Shirali, Sharlene, Rowlan, Jessica, Engel, Abbi L, Nazario, Jr, Marcos, Gonzalez, Kelie, Tong, Aspen, Neitz, Jay, Neitz, Maureen, Chao, Jennifer R

“…Complement dysregulation is a key component in the pathogenesis of age-related macular degeneration (AMD) and related diseases such as early-onset macular…”
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Insight from IOPN1LW/I Gene Haplotypes into the Cause and Prevention of Myopia by Neitz, Maureen, Wagner-Schuman, Melissa, Rowlan, Jessica S, Kuchenbecker, James A, Neitz, Jay

“…Nearsightedness (myopia) is a global health problem of staggering proportions that has driven the hunt for environmental and genetic risk factors in hopes of…”
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Tritan color vision deficiency may be associated with an OPN1SW splicing defect and haploinsufficiency by Neitz, Maureen, Krekling, Elise D, Hagen, Lene A, Pedersen, Hilde R, Rowlan, Jessica, Barborek, Rachel, Neitz, Jay, Crain, Adam, Baraas, Rigmor C

“…Here we present evidence implicating disrupted RNA splicing as a potential cause of inherited tritan color vision. Initially we tested 51 subjects for color…”
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Mutations in the Canine CNGB3 Channel Subunit in Two Achromatopsia Models Leads to Mis-Localization of CNGA3 Expression in Retinal Outer Segments by Gonzalez, Amaliris, Kaya, Asli, Rowlan, Jessica S., Komaromy, Andras M., Tanaka, Jacqueline C.

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