Search Results - "Rowe, Martin"

Epstein-Barr virus infection of polarized epithelial cells via the basolateral surface by memory B cell-mediated transfer infection by Shannon-Lowe, Claire, Rowe, Martin

“…Epstein Barr virus (EBV) exhibits a distinct tropism for both B cells and epithelial cells. The virus persists as a latent infection of memory B cells in…”
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Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics by Schmitz, Roland, Young, Ryan M., Ceribelli, Michele, Jhavar, Sameer, Xiao, Wenming, Zhang, Meili, Wright, George, Shaffer, Arthur L., Hodson, Daniel J., Buras, Eric, Liu, Xuelu, Powell, John, Yang, Yandan, Xu, Weihong, Zhao, Hong, Kohlhammer, Holger, Rosenwald, Andreas, Kluin, Philip, Müller-Hermelink, Hans Konrad, Ott, German, Gascoyne, Randy D., Connors, Joseph M., Rimsza, Lisa M., Campo, Elias, Jaffe, Elaine S., Delabie, Jan, Smeland, Erlend B., Ogwang, Martin D., Reynolds, Steven J., Fisher, Richard I., Braziel, Rita M., Tubbs, Raymond R., Cook, James R., Weisenburger, Dennis D., Chan, Wing C., Pittaluga, Stefania, Wilson, Wyndham, Waldmann, Thomas A., Rowe, Martin, Mbulaiteye, Sam M., Rickinson, Alan B., Staudt, Louis M.

“…RNA sequencing of Burkitt lymphoma tumours allows identification of mutations affecting the transcription factor TCF3, its negative regulator ID3 and the cell…”
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The Missing Link in Epstein-Barr Virus Immune Evasion: the BDLF3 Gene Induces Ubiquitination and Downregulation of Major Histocompatibility Complex Class I (MHC-I) and MHC-II by Quinn, Laura L, Williams, Luke R, White, Claire, Forrest, Calum, Zuo, Jianmin, Rowe, Martin

“…The ability of Epstein-Barr virus (EBV) to spread and persist in human populations relies on a balance between host immune responses and EBV immune evasion…”
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Unexpected patterns of Epstein–Barr virus transcription revealed by a High throughput PCR array for absolute quantification of viral mRNA by Tierney, Rosemary J, Shannon-Lowe, Claire D, Fitzsimmons, Leah, Bell, Andrew I, Rowe, Martin

“…Abstract We have validated a flexible, high-throughput and relatively inexpensive RT-QPCR array platform for absolute quantification of Epstein–Barr virus…”
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Quantitative Studies of Epstein-Barr Virus-Encoded MicroRNAs Provide Novel Insights into Their Regulation by AMOROSO, Richard, FITZSIMMONS, Leah, THOMAS, Wendy A, KELLY, Gemma L, ROWE, Martin, BELL, Andrew I

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Epigenetic and Transcriptional Changes Which Follow Epstein-Barr Virus Infection of Germinal Center B Cells and Their Relevance to the Pathogenesis of Hodgkin's Lymphoma by LEONARD, Sarah, WENBIN WEI, ANDERTON, Jennifer, VOCKERODT, Martina, ROWE, Martin, MURRAY, Paul G, WOODMAN, Ciaran B

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Features Distinguishing Epstein-Barr Virus Infections of Epithelial Cells and B Cells: Viral Genome Expression, Genome Maintenance, and Genome Amplification by SHANNON-LOWE, Claire, ADLAND, Emily, BELL, Andrew I, DELECLUSE, Henri-Jacques, RICKINSON, Alan B, ROWE, Martin

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The Switch from Latent to Productive Infection in Epstein-Barr Virus-Infected B Cells Is Associated with Sensitization to NK Cell Killing by Pappworth, Isabel Y, Wang, Eddie C, Rowe, Martin

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Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion by Rowe, Martin, Glaunsinger, Britt, van Leeuwen, Daphne, Zuo, Jianmin, Sweetman, David, Ganem, Don, Middeldorp, Jaap, Wiertz, Emmanuel J.H.J, Ressing, Maaike E

“…Relatively little is known about immune evasion during the productive phase of infection by the γ₁-herpesvirus Epstein-Barr virus (EBV). The use of a unique…”
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Cooperation between Epstein-Barr virus immune evasion proteins spreads protection from CD8+ T cell recognition across all three phases of the lytic cycle by Quinn, Laura L, Zuo, Jianmin, Abbott, Rachel J M, Shannon-Lowe, Claire, Tierney, Rosemary J, Hislop, Andrew D, Rowe, Martin

“…CD8+ T cell responses to Epstein-Barr virus (EBV) lytic cycle expressed antigens display a hierarchy of immunodominance, in which responses to epitopes of…”
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Memory B-cell reconstitution following allogeneic hematopoietic stem cell transplantation is an EBV-associated transformation event by Burns, David M., Tierney, Rose, Shannon-Lowe, Claire, Croudace, Jo, Inman, Charlotte, Abbotts, Ben, Nagra, Sandeep, Fox, Christopher P., Chaganti, Sridhar, Craddock, Charles F., Moss, Paul, Rickinson, Alan B., Rowe, Martin, Bell, Andrew I.

“…Allogeneic stem cell transplantation (allo-HSCT) provides a unique opportunity to track Epstein-Barr virus (EBV) infection in the context of the reconstituting…”
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An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link by Kelly, Gemma L, Long, Heather M, Stylianou, Julianna, Thomas, Wendy A, Leese, Alison, Bell, Andrew I, Bornkamm, Georg W, Mautner, Josef, Rickinson, Alan B, Rowe, Martin

“…Two factors contribute to Burkitt lymphoma (BL) pathogenesis, a chromosomal translocation leading to c-myc oncogene deregulation and infection with…”
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Epstein-Barr virus transcription factor Zta acts through distal regulatory elements to directly control cellular gene expression by Ramasubramanyan, Sharada, Osborn, Kay, Al-Mohammad, Rajaei, Naranjo Perez-Fernandez, Ijiel B, Zuo, Jianmin, Balan, Nicolae, Godfrey, Anja, Patel, Harshil, Peters, Gordon, Rowe, Martin, Jenner, Richard G, Sinclair, Alison J

“…Lytic replication of the human gamma herpes virus Epstein-Barr virus (EBV) is an essential prerequisite for the spread of the virus. Differential regulation of…”
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The Epstein-Barr Virus-Encoded BILF1 Protein Modulates Immune Recognition of Endogenously Processed Antigen by Targeting Major Histocompatibility Complex Class I Molecules Trafficking on both the Exocytic and Endocytic Pathways by JIANMIN ZUO, QUINN, Laura L, TAMBLYN, Jennifer, THOMAS, Wendy A, FEEDERLE, Regina, DELECLUSE, Henri-Jacques, HISLOP, Andrew D, ROWE, Martin

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The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradation by Zuo, Jianmin, Currin, Andrew, Griffin, Bryan D, Shannon-Lowe, Claire, Thomas, Wendy A, Ressing, Maaike E, Wiertz, Emmanuel J H J, Rowe, Martin

“…Epstein-Barr virus (EBV) is a human herpesvirus that persists as a largely subclinical infection in the vast majority of adults worldwide. Recent evidence…”
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Epstein-Barr virus evades CD4+ T cell responses in lytic cycle through BZLF1-mediated downregulation of CD74 and the cooperation of vBcl-2 by Zuo, Jianmin, Thomas, Wendy A, Haigh, Tracey A, Fitzsimmons, Leah, Long, Heather M, Hislop, Andrew D, Taylor, Graham S, Rowe, Martin

“…Evasion of immune T cell responses is crucial for viruses to establish persistence in the infected host. Immune evasion mechanisms of Epstein-Barr virus (EBV)…”
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Epstein-Barr Virus Latent Membrane Protein 1 Increases Calcium Influx through Store-operated Channels in B Lymphoid Cells by Dellis, Olivier, Arbabian, Atousa, Papp, Béla, Rowe, Martin, Joab, Irène, Chomienne, Christine

“…Ca2+ signaling plays an important role in B cell survival and activation and is dependent on Ca2+ trapped in the endoplasmic reticulum (ER) and on…”
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Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral IRF3 Modulates Major Histocompatibility Complex Class II (MHC-II) Antigen Presentation through MHC-II Transactivator-Dependent and -Independent Mechanisms: Implications for Oncogenesis by Zuo, Jianmin, Hislop, Andrew D, Leung, Carol S, Sabbah, Shereen, Rowe, Martin

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Suppression of the LMP2A target gene, EGR-1, protects Hodgkin's lymphoma cells from entry to the EBV lytic cycle by Vockerodt, Martina, Wei, Wenbin, Nagy, Eszter, Prouzova, Zuzana, Schrader, Alexandra, Kube, Dieter, Rowe, Martin, Woodman, Ciaran B, Murray, Paul G

“…Hodgkin's lymphoma is unusual among B cell lymphomas, in so far as the malignant Hodgkin/Reed–Sternberg (HRS) cells lack a functional B cell receptor (BCR), as…”
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Herpesviruses placating the unwilling host: manipulation of the MHC class II antigen presentation pathway by Zuo, Jianmin, Rowe, Martin

“…Lifelong persistent infection by herpesviruses depends on the balance between host immune responses and viral immune evasion. CD4 T cells responding to…”
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