Search Results - "Rowan, M.J."

Developmental dependence, the role of the kinases p38 MAPK and PKC, and the involvement of tumor necrosis factor-R1 in the induction of mGlu-5 LTD in the dentate gyrus by Wang, Q, Chang, L, Rowan, M.J, Anwyl, R

“…Abstract The mechanisms of mGluR-LTD were studied in the dentate gyrus in vitro . The most effective protocol for inducing mGluR-LTD in 6–8 week animals was…”
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Muscarinic acetylcholine receptor-dependent induction of persistent synaptic enhancement in rat hippocampus in vivo by Li, S, Cullen, W.K, Anwyl, R, Rowan, M.J

“…Abstract Presynaptic terminal autoinhibitory muscarinic acetylcholine (ACh) receptors are predominantly of the M2/M4 subtypes and antagonists at these…”
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A role for protein kinase A and protein kinase Mζ in muscarinic acetylcholine receptor–initiated persistent synaptic enhancement in rat hippocampus in vivo by Hayes, J, Li, S, Anwyl, R, Rowan, M.J

“…Abstract Antagonists at presynaptic muscarinic autoreceptors increase endogenous acetylcholine (ACh) release and enhance cognition but little is known…”
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Synaptically stimulated induction of group i metabotropic glutamate receptor-dependent long-term depression and depotentiation is inhibited by prior activation of metabotropic glutamate receptors and PROTEIN KINASE C by Wu, J, Rowan, M.J, Anwyl, R

“…We have investigated metaplasticity of the group I metabotropic glutamate receptor (mGluR)-dependent long-term depression (LTD) and depotentiation (DP) induced…”
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Metabotropic glutamate receptor-induced homosynaptic long-term depression and depotentiation in the dentate gyrus of the rat hippocampus in vitro by O'Mara, S.M., Rowan, M.J., Anwyl, R.

“…We have investigated the role of metabotropic glutamate receptors (mGluR) in the induction of homosynaptic long-term depression (LTD) and depotentiation (DP)…”
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P.1.27 Functional and molecular correlates of synaptic plasticity in a gene–environment combination rat model of depression by Musazzi, L, Barbiero, V.S, Mallei, A, Mathè, A, El Khoury, A, Gruber, S.H, Racagni, G, Ryan, B.K, Rowan, M.J, Popoli, M

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Synaptic memory mechanisms: Alzheimer's disease amyloid beta-peptide-induced dysfunction by Rowan, M J, Klyubin, I, Wang, Q, Hu, N W, Anwyl, R

“…There is growing evidence that mild cognitive impairment in early AD (Alzheimer's disease) may be due to synaptic dysfunction caused by the accumulation of…”
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The role of N-methyl-D-aspartate receptors in the generation of short-term potentiation in the rat hippocampus by Anwyl, R, Mulkeen, D, Rowan, M J

“…The effects of stimulus intensity and the N-methyl-D-aspartate (NMDA) antagonist 2-amino-5-phosphonovalerate (AP5) were studied on the induction of short-term…”
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Potentiation of N-methyl- d-aspartate-receptor-mediated currents detected using the excised patch technique in the hippocampal dentate gyrus by O'Connor, J.J., Wu, J., Rowan, M.J., Anwyl, R.

“…The excised patch mode of the patch-clamp technique has been used to record isolated patch N-methyl- d-aspartate-receptor-mediated currents (patch…”
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Synaptic plasticity disruption by amyloid beta protein: modulation by potential Alzheimer's disease modifying therapies by Rowan, M J, Klyubin, I, Wang, Q, Anwyl, R

“…AD (Alzheimer's disease) is characterized by a progressive and devastating mental decline that is usually presaged by impairment of a form of memory dependent…”
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Autonomous Purkinje cell activation instructs bidirectional motor learning through evoked dendritic calcium signaling by Bonnan, Audrey, Rowan, Matthew M. J., Baker, Christopher A., Bolton, M. McLean, Christie, Jason M.

“…The signals in cerebellar Purkinje cells sufficient to instruct motor learning have not been systematically determined. Therefore, we applied optogenetics in…”
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Mechanisms underlying the inhibition of long-term potentiation by preconditioning stimulation in the hippocampus in vitro by Gisabella, B, Rowan, M.J, Anwyl, R

“…We have investigated the mechanisms underlying a form of metaplasticity, namely the inhibition by preconditioning stimulation of high frequency stimulation…”
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Role of protein kinases A and C in the induction of mglur-dependent long-term depression in the medial perforant path of the rat dentate gyrus in vitro by HUANG, L.-Q, ROWAN, M. J, ANWYL, R

“…The involvement of protein kinases A and C in the induction of low frequency stimulation-induced long-term depression (LTD) in the medial perforant path of the…”
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A persistent reduction in short-term facilitation accompanies long-term potentiation in the CA1 area in the intact hippocampus by Li, S, Anwyl, R, Rowan, M.J

“…Exploration of the nature of the relationship between short-term and long-term synaptic plasticity should aid our understanding of their roles in brain…”
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Low-frequency stimulation induces homosynaptic depotentiation but not long-term depression of synaptic transmission in the adult anaesthetized and awake rat hippocampus in vivo by Doyle, C.A, Cullen, W.K, Rowan, M.J, Anwyl, R

“…The induction of homosynaptic long-term depression and depotentiation of previously established long-term potentiation was investigated in the CA1 hippocampal…”
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Dantrolene inhibits long-term depression and depotentiation of synaptic transmission in the rat dentate gyrus by O'Mara, S.M., Rowan, M.J., Anwyl, R.

“…The involvement of Ca release from intracellular stores in the induction of long-term depression and depotentiation of excitatory synaptic transmission was…”
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Early spatial memory deficit induced by 2,5-hexanedione in the rat by Carney, R, Dardis, C, Cullen, W.K, Felipo, V, Anwyl, R, Rowan, M.J

“…2,5-Hexanedione (2,5-HD), the major common neurotoxic metabolite of n-hexane and methyl n-butyl ketone, causes a delayed neuropathy with associated…”
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Activation of group II metabotropic glutamate receptors results in long-term potentiation following preconditioning stimulation in the dentate gyrus by Rush, A.M, Wu, J, Rowan, M.J, Anwyl, R

“…The role of group II metabotropic glutamate receptors in the induction/expression of long-term potentiation has been investigated in the medial perforant path…”
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Evidence for involvement of the neuronal isoform of nitric oxide synthase during induction of long-term potentiation and long-term depression in the rat dentate gyros in vitro by Wu, J, Wang, Y, Rowan, M.J, Anwyl, R

“…The possible role of nitric oxide in the induction of long-term potentiation and long-term depression of field excitatory postsynaptic potentials in the…”
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Block of theta-burst-induced long-term potentiation by (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid: further evidence against long-term potentiation as a model for learning by Hölscher, C, Anwyl, R, Rowan, M.J

“…It has been previously reported that block of high-frequency stimulation-induced long-term potentiation of synaptic transmission in the hippocampus does not…”
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