Search Results - "Rovsnik, Urska"

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    Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM by Bergh, Cathrine, Rovšnik, Urška, Howard, Rebecca, Lindahl, Erik

    Published in eLife (30-01-2024)
    “…Ligand-gated ion channels transduce electrochemical signals in neurons and other excitable cells. Aside from canonical ligands, phospholipids are thought to…”
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    Journal Article
  2. 2

    Automated simulation-based membrane protein refinement into cryo-EM data by Yvonnesdotter, Linnea, Rovšnik, Urška, Blau, Christian, Lycksell, Marie, Howard, Rebecca Joy, Lindahl, Erik

    Published in Biophysical journal (11-07-2023)
    “…The resolution revolution has increasingly enabled single-particle cryogenic electron microscopy (cryo-EM) reconstructions of previously inaccessible systems,…”
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  3. 3

    Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel by Lycksell, Marie, Rovšnik, Urška, Hanke, Anton, Martel, Anne, Howard, Rebecca J, Lindahl, Erik

    “…Pentameric ligand-gated ion channels (pLGICs) perform electrochemical signal transduction in organisms ranging from bacteria to humans. Among the prokaryotic…”
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  4. 4

    Probing solution structure of the pentameric ligand-gated ion channel GLIC by small-angle neutron scattering by Lycksell, Marie, Rovšnik, Urška, Bergh, Cathrine, Johansen, Nicolai T., Martel, Anne, Porcar, Lionel, Arleth, Lise, Howard, Rebecca J., Lindahl, Erik

    “…Pentameric ligand-gated ion channels undergo subtle conformational cycling to control electrochemical signal transduction in many kingdoms of life. Several…”
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    Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations by Rovšnik, Urška, Zhuang, Yuxuan, Forsberg, Björn O, Carroni, Marta, Yvonnesdotter, Linnea, Howard, Rebecca J, Lindahl, Erik

    Published in Life science alliance (01-08-2021)
    “…Ligand-gated ion channels are critical mediators of electrochemical signal transduction across evolution. Biophysical and pharmacological characterization of…”
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    Journal Article
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