Search Results - "Roviello, Giovanni N."
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Molecular Basis of the Therapeutical Potential of Clove ( Syzygium aromaticum L.) and Clues to Its Anti-COVID-19 Utility
Published in Molecules (Basel, Switzerland) (26-03-2021)“…The current COronaVIrus Disease 19 (COVID-19) pandemic caused by SARS-CoV-2 infection is enormously affecting the worldwide health and economy. In the wait for…”
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An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies
Published in Pharmacology & therapeutics (Oxford) (01-03-2014)“…HMGB1 (High-Mobility Group Box-1) is a nuclear protein that acts as an architectural chromatin-binding factor involved in the maintenance of nucleosome…”
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Interaction of Laurusides 1 and 2 with the 3C-like Protease (M pro ) from Wild-Type and Omicron Variant of SARS-CoV-2: A Molecular Dynamics Study
Published in International journal of molecular sciences (01-03-2023)“…(bay laurel) is a natural source of biological compounds, and some of its extracts and phytocompounds are also endowed with antiviral activity toward the…”
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Potential Anti-SARS-CoV-2 Molecular Strategies
Published in Molecules (Basel, Switzerland) (24-02-2023)“…Finding effective antiviral molecular strategies was a main concern in the scientific community when the severe acute respiratory syndrome coronavirus 2…”
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Forest-bathing and physical activity as weapons against COVID-19: a review
Published in Environmental chemistry letters (01-02-2022)“…Strengthening the immune system in order to better withstand the threat of COVID-19 is an important way to ensure the protection of our health against the…”
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The Role of Nutrition and Forest-Bathing in the Physical Rehabilitation of Physically Inactive Patients: From the Molecular Aspects to New Nature-Inspired Techniques
Published in International journal of environmental research and public health (31-12-2022)“…Physical rehabilitation plays a fundamental role in the management of individuals with disabilities associated with age-related muscle loss or affected by…”
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The Potential Role of Vaccines in Preventing Antimicrobial Resistance (AMR): An Update and Future Perspectives
Published in Vaccines (Basel) (01-02-2023)“…In the modern era, the consumption of antibiotics represents a revolutionary weapon against several infectious diseases, contributing to the saving of millions…”
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In Silico Investigation on the Interaction of Chiral Phytochemicals from Opuntia ficus-indica with SARS-CoV-2 Mpro
Published in Symmetry (Basel) (01-06-2021)“…Opuntia ficus-indica is a cactaceous plant native to America but, nowadays, widely found worldwide, having been the most common domesticated species of cactus…”
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Exploring the Protective Effect of Food Drugs against Viral Diseases: Interaction of Functional Food Ingredients and SARS-CoV-2, Influenza Virus, and HSV
Published in Life (Basel, Switzerland) (01-02-2023)“…A complex network of processes inside the human immune system provides resistance against a wide range of pathologies. These defenses form an innate and…”
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Intestinimonas-like bacteria are important butyrate producers that utilize Nε-fructosyllysine and lysine in formula-fed infants and adults
Published in Journal of functional foods (01-07-2020)“…[Display omitted] •Fecal microbiota of adults is able to convert the Nε-fructosyllysine into butyrate.•The fecal microbiota of formula-fed but not breast-fed…”
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Advances in Amino Acid-Based Chemistry
Published in Pharmaceuticals (Basel, Switzerland) (01-10-2023)“…Numerous applications of amino acid-based compounds and peptide derivatives in different biomedicine- and nanotechnology-related fields were described in the…”
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Protein-Targeting Drug Discovery
Published in Biomolecules (Basel, Switzerland) (29-10-2023)“…Protein-driven biological processes play a fundamental role in biomedicine because they are related to pathologies of enormous social impact, such as cancer,…”
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Nucleic Acid Probes in Bio-Imaging and Diagnostics: Recent Advances in ODN-Based Fluorescent and Surface-Enhanced Raman Scattering Nanoparticle and Nanostructured Systems
Published in Molecules (Basel, Switzerland) (01-04-2023)“…Raman nanoparticle probes are a potent class of optical labels for the interrogation of pathological and physiological processes in cells, bioassays, and…”
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Spectroscopic and In Silico Studies on the Interaction of Substituted Pyrazolo[1,2-a]benzo[1,2,3,4]tetrazine-3-one Derivatives with c-Myc G4-DNA
Published in International journal of molecular sciences (02-06-2021)“…Herein we describe a combined experimental and in silico study of the interaction of a series of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives (PBTs)…”
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Nucleic Acids as Biotools at the Interface between Chemistry and Nanomedicine in the COVID-19 Era
Published in International journal of molecular sciences (14-04-2022)“…The recent development of mRNA vaccines against the SARS-CoV-2 infection has turned the spotlight on the potential of nucleic acids as innovative prophylactic…”
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Willardiine and Its Synthetic Analogues: Biological Aspects and Implications in Peptide Chemistry of This Nucleobase Amino Acid
Published in Pharmaceuticals (Basel, Switzerland) (01-10-2022)“…Willardiine is a nonprotein amino acid containing uracil, and thus classified as nucleobase amino acid or nucleoamino acid, that together with isowillardiine…”
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Structural and Functional Characterization of New SsoPox Variant Points to the Dimer Interface as a Driver for the Increase in Promiscuous Paraoxonase Activity
Published in International journal of molecular sciences (01-03-2020)“…Increasing attention is more and more directed toward the thermostable Phosphotriesterase-Like-Lactonase (PLL) family of enzymes, for the efficient and…”
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A Survey on Computational Methods in Drug Discovery for Neurodegenerative Diseases
Published in Biomolecules (Basel, Switzerland) (19-10-2024)“…Currently, the age structure of the world population is changing due to declining birth rates and increasing life expectancy. As a result, physicians worldwide…”
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New N4-Donor Ligands as Supramolecular Guests for DNA and RNA: Synthesis, Structural Characterization, In Silico, Spectrophotometric and Antimicrobial Studies
Published in Molecules (Basel, Switzerland) (01-01-2023)“…The present work reports the synthesis of new N4-donor compounds carrying p-xylyl spacers in their structure. Different Schiff base aliphatic N-donors were…”
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Dancing with Nucleobases: Unveiling the Self-Assembly Properties of DNA and RNA Base-Containing Molecules for Gel Formation
Published in Gels (01-01-2024)“…Nucleobase-containing molecules are compounds essential in biology due to the fundamental role of nucleic acids and, in particular, G-quadruplex DNA and RNA in…”
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