Search Results - "Roveto, Philip M."

A Selective Prostaglandin E2 Receptor Subtype 2 (EP2) Antagonist Increases the Macrophage-Mediated Clearance of Amyloid-Beta Plaques by Fox, Brian M, Beck, Hilary P, Roveto, Philip M, Kayser, Frank, Cheng, Qingwen, Dou, Hannah, Williamson, Toni, Treanor, James, Liu, Hantao, Jin, Lixia, Xu, Guifen, Ma, Ji, Wang, Songli, Olson, Steven H

“…A high-throughput screen resulted in the discovery of benzoxazepine 1, an EP2 antagonist possessing low microsomal stability and potent CYP3A4 inhibition…”
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Effects of surface skewness on local shear stresses, biofilm activity, and microbial communities for wastewater treatment by Roveto, Philip M., Gupta, Adwaith, Schuler, Andrew J.

“…•Negative skewness led to most rapid biofilm growth and nitrate production.•Computational fluid dynamics modeling provided insights to local shear…”
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Performance and diversity responses of nitrifying biofilms developed on varied materials and topographies to stepwise increases of aeration by Roveto, Philip M., Schuler, Andrew J.

“…[Display omitted] •Nitrifying biofilms grown on different surfaces were evaluated under varied aeration.•Surface type affected nitrification rates differently…”
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An intramolecular inverse electron demand Diels-Alder approach to annulated α-carbolines by Ma, Zhiyuan, Ni, Feng, Woo, Grace H C, Lo, Sie-Mun, Roveto, Philip M, Schaus, Scott E, Snyder, John K

“…Intramolecular inverse electron demand cycloadditions of isatin-derived 1,2,4-triazines with acetylenic dienophiles tethered by amidations or…”
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Effects of Methyl, Ester, and Amine Surface Groups on Microbial Activity and Communities in Nitrifying Biofilms by Roveto, Philip M, Benavidez, Angelica, Schuler, Andrew J

“…The objective of this study was to determine how different attachment surface chemistries affected the initial and long-term performance and microbial…”
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Novel 2,3-Dihydro-1,4-Benzoxazines as Potent and Orally Bioavailable Inhibitors of Tumor-Driven Angiogenesis by La, Daniel S, Belzile, Julie, Bready, James V, Coxon, Angela, DeMelfi, Thomas, Doerr, Nicholas, Estrada, Juan, Flynn, Julie C, Flynn, Shaun R, Graceffa, Russell F, Harriman, Shawn P, Larrow, Jay F, Long, Alexander M, Martin, Matthew W, Morrison, Michael J, Patel, Vinod F, Roveto, Philip M, Wang, Ling, Weiss, Matthew M, Whittington, Douglas A, Teffera, Yohannes, Zhao, Zhiyang, Polverino, Anthony J, Harmange, Jean-Christophe

“…Angiogenesis is vital for solid tumor growth, and its prevention is a proven strategy for the treatment of disease states such as cancer. The vascular…”
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Novel pyrrolidine melanin-concentrating hormone receptor 1 antagonists with reduced hERG inhibition by Fox, Brian M., Natero, Reina, Richard, Kevin, Connors, Richard, Roveto, Philip M., Beckmann, Holger, Haller, Katrin, Golde, Justin, Xiao, Shou-Hua, Kayser, Frank

“…We discovered novel pyrrolidine MCHR1 antagonist 1 possessing moderate potency. Profiling of pyrrolidine 1 demonstrated that it was an inhibitor of the hERG…”
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A Selective Prostaglandin E 2 Receptor Subtype 2 (EP2) Antagonist Increases the Macrophage-Mediated Clearance of Amyloid-Beta Plaques by Fox, Brian M., Beck, Hilary P., Roveto, Philip M., Kayser, Frank, Cheng, Qingwen, Dou, Hannah, Williamson, Toni, Treanor, James, Liu, Hantao, Jin, Lixia, Xu, Guifen, Ma, Ji, Wang, Songli, Olson, Steven H.

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Biointerfacial Studies of Nitrifying Biofilms on Physically and Chemically Modified Surfaces by Roveto, Philip M

“…Interactions between bacteria and surfaces during the initiation of biofilm formation are complex phenomena with significant and wide-ranging implications for…”
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