Search Results - "Routledge, Michael"

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  1. 1

    The contribution of PM2.5 to cardiovascular disease in China by Zhang, Shuqi, Routledge, Michael N.

    “…China is experiencing rapid urbanization and industrialization with correspondingly high levels of air pollution. Although the harm of PM 2.5 has been long…”
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    Journal Article
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    Estimating the risk of aflatoxin-induced liver cancer in Tanzania based on biomarker data by Kimanya, Martin E, Routledge, Michael N, Mpolya, Emmanuel, Ezekiel, Chibundu N, Shirima, Candida P, Gong, Yun Yun

    Published in PloS one (11-03-2021)
    “…Evidence about the magnitude of the aflatoxin menace can help policy makers appreciate the importance of the problem and strengthen policies to support…”
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    Identification of rhein as the metabolite responsible for toxicity of rhubarb anthraquinones by Cheng, Ying, Zhang, Huiqin, Qu, Lejing, He, Ying, Routledge, Michael N., Yun Gong, Yun, Qiao, Boling

    Published in Food chemistry (30-11-2020)
    “…•Rats fed with rhubarb anthraquinones (RA) showed colonic toxicity.•The RA metabolites in the feces were investigated by HPLC.•The metabolite rhein accumulated…”
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    Molecular explication of grape berry-fungal infections and their potential application in recent postharvest infection control strategies by Solairaj, Dhanasekaran, Yang, Qiya, Guillaume Legrand, Ngolong Ngea, Routledge, Michael N., Zhang, Hongyin

    Published in Trends in food science & technology (01-10-2021)
    “…Grapes are one of the highly valued non-climacteric fruits that can be consumed fresh or used to produce numerous food products and dietary supplements…”
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    Efficacy of epsilon-poly-L-lysine inhibition of postharvest blue mold in apples and potential mechanisms by Dou, Yong, Routledge, Michael N, Gong, Yunyun, Godana, Esa Abiso, Dhanasekaran, Solairaj, Yang, Qiya, Zhang, Xiaoyun, Zhang, Hongyin

    Published in Postharvest biology and technology (01-01-2021)
    “…•ε-PL controlled the blue mold decay of apples effectively.•The inhibitory effects of ε-PL against P. expansum were confirmed in vitro.•ε-PL induced apples to…”
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  6. 6

    Effects of aflatoxin and fumonisin on gene expression of growth factors and inflammation-related genes in a human hepatocyte cell line by Wu, Hang, Xu, Ya, Gong, Yun Yun, Huntriss, John, Routledge, Michael N

    Published in Mutagenesis (24-04-2024)
    “…Aflatoxin B1 (AFB1) and fumonisin B1 (FB1) are mycotoxins widely distributed in maize and maized-based products, often occurring together. The implications of…”
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  7. 7

    Recent trends in detecting, controlling, and detoxifying of patulin mycotoxin using biotechnology methods by Ngolong Ngea, Guillaume Legrand, Yang, Qiya, Castoria, Raffaello, Zhang, Xiaoyun, Routledge, Michael N, Zhang, Hongyin

    “…Patulin (PAT) is a mycotoxin that can contaminate many foods and especially fruits and fruit‐based products. Therefore, accurate and effective testing is…”
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  8. 8

    A prospective study of growth and biomarkers of exposure to aflatoxin and fumonisin during early childhood in Tanzania by Shirima, Candida P, Kimanya, Martin E, Routledge, Michael N, Srey, Chou, Kinabo, Joyce L, Humpf, Hans-Ulrich, Wild, Christopher P, Tu, Yu-Kang, Gong, Yun Yun

    Published in Environmental health perspectives (01-02-2015)
    “…Aflatoxin and fumonisin are toxic food contaminants. Knowledge about effects of their exposure and coexposure on child growth is inadequate. We investigated…”
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    Mechanism of cellular uptake of genotoxic silica nanoparticles by Mu, Qingshan, Hondow, Nicole S, Krzemiński, Lukasz, Brown, Andy P, Jeuken, Lars J C, Routledge, Michael N

    Published in Particle and fibre toxicology (23-07-2012)
    “…Mechanisms for cellular uptake of nanoparticles have important implications for nanoparticulate drug delivery and toxicity. We have explored the mechanism of…”
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  10. 10

    An integrated 3D cell-based electrochemical biosensor for neurotoxicity assessment of organophosphorus pesticides by Wei, Xiaoou, Liu, Chao, Zhang, Xinai, Li, Zhihua, Wang, Xinyu, Xu, Yiwei, Shi, Jiyong, Sun, Quancai, Routledge, Michael N., Zhang, Di, Zou, Xiaobo

    Published in Sensors and actuators. B, Chemical (01-02-2023)
    “…This work presents an integrated three-dimensional (3D) cell-based electrochemical biosensor to assess the neurotoxicity of organophosphorus pesticides (OPs)…”
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    Early life exposure to dietary aflatoxins, health impact and control perspectives: A review by Ismail, Amir, Naeem, Iqra, Gong, Yun Yun, Routledge, Michael N., Akhtar, Saeed, Riaz, Muhammad, Ramalho, Leandra Naira Zambelli, de Oliveira, Carlos Augusto Fernandes, Ismail, Zubair

    Published in Trends in food science & technology (01-06-2021)
    “…The initial stages of human life including the fetal period, infancy and early childhood are the most critical periods of human growth and development. Due to…”
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  13. 13

    Estimating the health burden of aflatoxin attributable stunting among children in low income countries of Africa by Rasheed, Hifza, Xu, Ya, Kimanya, Martin E., Pan, Xiaoxi, Li, Zhihua, Zou, Xiaobo, Shirima, Candida P., Holmes, Melvin, Routledge, Michael N., Gong, Yun Yun

    Published in Scientific reports (15-01-2021)
    “…Numerous population-based studies have documented high prevalence of aflatoxin associated childhood stunting in low income countries. We provide an estimate of…”
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  14. 14

    The effect of individual and mixtures of mycotoxins and persistent organochloride pesticides on oestrogen receptor transcriptional activation using in vitro reporter gene assays by Eze, Ukpai A., Huntriss, John, Routledge, Michael N., Gong, Yun Yun, Connolly, Lisa

    Published in Food and chemical toxicology (01-08-2019)
    “…The mycotoxins zearalenone (ZEN) and alpha-zearalenone (α-ZOL), which are common contaminants of agri-food products, are known for their oestrogenic potential…”
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  15. 15

    Risk assessment of deoxynivalenol in high-risk area of China by human biomonitoring using an improved high throughput UPLC-MS/MS method by Deng, Chunli, Li, Chenglong, Zhou, Shuang, Wang, Xiaodan, Xu, Haibin, Wang, Dan, Gong, Yun Yun, Routledge, Michael N., Zhao, Yunfeng, Wu, Yongning

    Published in Scientific reports (01-03-2018)
    “…A risk assessment of deoxynivalenol (DON) was recently conducted for the residents in Henan province, China, where wheat as the staple food are highly…”
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    Prevalence and Exposure Assessment of Aflatoxins Through Black Tea Consumption in the Multan City of Pakistan and the Impact of Tea Making Process on Aflatoxins by Ismail, Amir, Akhtar, Saeed, Riaz, Muhammad, Gong, Yun Yun, Routledge, Michael N, Naeem, Iqra

    Published in Frontiers in microbiology (31-03-2020)
    “…Aflatoxins are the highly toxic secondary metabolites of certain fungi, being mainly produced by and . Aflatoxins are classified as group 1 category…”
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  17. 17

    Super-Sensitive LC-MS Analyses of Exposure Biomarkers for Multiple Mycotoxins in a Rural Pakistan Population by Xia, Lei, Rasheed, Hifza, Routledge, Michael N, Wu, Hang, Gong, Yun Yun

    Published in Toxins (04-03-2022)
    “…High levels of mycotoxin contamination have been reported in various food commodities in Pakistan, however, there has been no exposure assessment study using…”
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    Organ Specific Differences in Alteration of Aquaporin Expression in Rats Treated with Sennoside A, Senna Anthraquinones and Rhubarb Anthraquinones by Wang, Zhaoyang, Cheng, Ying, Su, Wenting, Zhang, Hongxia, Li, Chu, Routledge, Michael N., Gong, Yunyun, Qiao, Boling

    “…Senna and rhubarb are often used as routine laxatives, but there are differences in mechanism of action and potential side effects. Here, we studied…”
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