Search Results - "Routenberg, David"
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Quantification of the affinities and kinetics of protein interactions using silicon nanowire biosensors
Published in Nature nanotechnology (27-05-2012)“…Monitoring the binding affinities and kinetics of protein interactions is important in clinical diagnostics and drug development because such information is…”
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Optimal signal-to-noise ratio for silicon nanowire biochemical sensors
Published in Applied physics letters (27-06-2011)“…The signal-to-noise ratio (SNR) for silicon nanowire field-effect transistors operated in an electrolyte environment is an essential figure-of-merit to…”
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Label-free immunodetection with CMOS-compatible semiconducting nanowires
Published in Nature (01-02-2007)“…Semiconducting nanowires have the potential to function as highly sensitive and selective sensors for the label-free detection of low concentrations of…”
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Observation of Plasmon Propagation, Redirection, and Fan-Out in Silver Nanowires
Published in Nano letters (01-08-2006)“…We report the coupling of free-space photons (vacuum wavelength of 830 nm) to surface plasmon modes of a silver nanowire. The launch of propagating plasmons,…”
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Brain Tissue-Derived Extracellular Vesicles in Alzheimer's Disease Display Altered Key Protein Levels Including Cell Type-Specific Markers
Published in Journal of Alzheimer's disease (01-01-2022)“…Brain tissue-derived extracellular vesicles (bdEVs) play neurodegenerative and protective roles, including in Alzheimer's disease (AD). Extracellular vesicles…”
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Regenerative Electronic Biosensors Using Supramolecular Approaches
Published in ACS nano (28-05-2013)“…A supramolecular interface for Si nanowire FETs has been developed with the aim of creating regenerative electronic biosensors. The key to the approach is…”
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hTERT-Immortalized Mesenchymal Stem Cell-Derived Extracellular Vesicles: Large-Scale Manufacturing, Cargo Profiling, and Functional Effects in Retinal Epithelial Cells
Published in Cells (Basel, Switzerland) (17-05-2024)“…As the economic burden associated with vision loss and ocular damage continues to rise, there is a need to explore novel treatment strategies. Extracellular…”
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Toward a human brain extracellular vesicle atlas: Characteristics of extracellular vesicles from different brain regions, including small RNA and protein profiles
Published in Interdisciplinary medicine (Richmond, Vic. Print) (01-10-2023)“…Extracellular vesicles (EVs) are released from different cell types in the central nervous system (CNS) and play roles in regulating physiological and…”
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Elevation of neural injury markers in patients with neurologic sequelae after hospitalization for SARS-CoV-2 infection
Published in iScience (19-08-2022)“…Patients with SARS-CoV-2 infection (COVID-19) risk developing long-term neurologic symptoms after infection. Here, we identify biomarkers associated with…”
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Structural and functional diversity of metalloproteinases encoded by the Bacteroides fragilis pathogenicity island
Published in The FEBS journal (01-06-2014)“…Bacteroides fragilis causes the majority of anaerobic infections in humans. The presence of a pathogenicity island in the genome discriminates pathogenic and…”
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Relationships of APOE Genotypes With Small RNA and Protein Cargo of Brain Tissue Extracellular Vesicles From Patients With Late-Stage AD
Published in Neurology. Genetics (01-12-2022)“…Variants of the apolipoprotein E gene are the greatest known risk factors for sporadic Alzheimer disease (AD). Three major isoform alleles, , and , encode and…”
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Temperature dependence of 1/f noise mechanisms in silicon nanowire biochemical field effect transistors
Published in Applied physics letters (13-12-2010)“…The 1/f noise of silicon nanowire biochemical field effect transistors is fully characterized from weak to strong inversion in the temperature range 100-300 K…”
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The EV antibody database: An interactive database of curated antibodies for extracellular vesicle and nanoparticle research
Published in Extracellular Vesicle (Online) (01-06-2024)“…Antibodies are critical tools for research into extracellular vesicles (EVs) and other extracellular nanoparticles (ENPs), where they can be used for their…”
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Microfluidic probe: a new tool for integrating microfluidic environments and electronic wafer-probing
Published in Lab on a chip (07-01-2010)“…We demonstrate a new tool for integrating microfluidic channels with commonly used electronic probing techniques. The "microfluidic probe" allows rapid and…”
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Erratum: "Temperature dependence of 1∕f noise mechanisms in silicon nanowire biochemical field effect transistors" [Appl. Phys. Lett. 97, 243501 (2010)]
Published in Applied physics letters (09-05-2011)“…[This corrects the article on p. 243501 in vol. 97, PMID: 21221250.][This corrects the article on p. 243501 in vol. 97, PMID: 21221250.]…”
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High-Throughput Multiplexed Peptide-Centric Profiling Illustrates Both Substrate Cleavage Redundancy and Specificity in the MMP Family
Published in Chemistry & biology (20-08-2015)“…Matrix metalloproteinases (MMPs) play incompletely understood roles in health and disease. Knowing the MMP cleavage preferences is essential for a better…”
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Abstract 3637: Ultrasensitive assays for combined detection of CEA+ extracellular vesicles and soluble CEA
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Colorectal cancer (CRC) is the third most common cancer worldwide and is the second leading cause of cancer death in the United States…”
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[Formula Omitted] Noise of Silicon Nanowire BioFETs
Published in IEEE electron device letters (01-06-2010)“…The [Formula Omitted] noise of silicon nanowire (NW) biological field-effect transistors (NW FETs with exposed channels) is characterized and compared with…”
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