Search Results - "Rousset, Xavier"
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Lecithin Cholesterol Acyltransferase: An Anti- or Pro-atherogenic Factor?
Published in Current atherosclerosis reports (01-06-2011)“…Lecithin cholesterol acyl transferase (LCAT) is a plasma enzyme that esterifies cholesterol and raises high-density lipoprotein cholesterol, but its role in…”
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Lecithin: cholesterol acyltransferase – from biochemistry to role in cardiovascular disease
Published in Current opinion in endocrinology, diabetes, and obesity (01-04-2009)“…We discuss the latest findings on the biochemistry of lecithin : cholesterol acyltransferase (LCAT), the effect of LCAT on atherosclerosis, clinical features…”
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Increased plasma cholesterol esterification by LCAT reduces diet-induced atherosclerosis in SR-BI knockout mice[S]
Published in Journal of lipid research (01-07-2015)“…LCAT, a plasma enzyme that esterifies cholesterol, has been proposed to play an antiatherogenic role, but animal and epidemiologic studies have yielded…”
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Effect of recombinant human lecithin cholesterol acyltransferase infusion on lipoprotein metabolism in mice
Published in The Journal of pharmacology and experimental therapeutics (01-10-2010)“…Lecithin cholesterol acyl transferase (LCAT) deficiency is associated with low high-density lipoprotein (HDL) and the presence of an abnormal lipoprotein…”
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Metabolic Signatures of Tumor Responses to Doxorubicin Elucidated by Metabolic Profiling in Ovo
Published in Metabolites (28-06-2020)“…Background: Dysregulated cancer metabolism is associated with acquired resistance to chemotherapeutic treatment and contributes to the activation of cancer…”
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Anti-Tumor Effects of Bak-Proteoliposomes against Glioblastoma
Published in Molecules (Basel, Switzerland) (01-09-2015)“…Despite palliative treatments, glioblastoma (GBM) remains a devastating malignancy with a mean survival of about 15 months after diagnosis. Programmed…”
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Human apolipoprotein A-II associates with triglyceride-rich lipoproteins in plasma and impairs their catabolism
Published in Journal of lipid research (01-12-2006)“…Postprandial hypertriglyceridemia and low plasma HDL levels, which are principal features of the metabolic syndrome, are displayed by transgenic mice…”
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Apolipoprotein A-II is catabolized in the kidney as a function of its plasma concentration
Published in Journal of lipid research (01-10-2007)“…We investigated in vivo catabolism of apolipoprotein A-II (apo A-II), a major determinant of plasma HDL levels. Like apoA-I, murine apoA-II (mapoA-II) and…”
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Consumer vulnerability to dynamic pricing in online environments
Published in Applied economics (27-05-2024)“…This article examines consumer vulnerability perceptions of dynamic pricing in online environments. Based on an online survey of 763 French web-users, we show…”
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An analytical framework for retailer price and advertising decisions for products with temperature-sensitive demand
Published in Applied economics (08-11-2019)“…The demand for weather-sensitive products, such as beverages, ice creams, or chocolate varies with changes in temperature. Yet, retailers lack a framework to…”
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PD-1/PD-L1 Checkpoint Inhibitors Are Active in the Chicken Embryo Model and Show Antitumor Efficacy In Ovo
Published in Cancers (23-06-2022)“…(1) Purpose: To assess the use of the chicken embryo (in ovo) model as an alternative in vivo model for immuno-oncology (IO) drug development, focusing on…”
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The CAM Model-Q&A with Experts
Published in Cancers (28-12-2022)“…The chick chorioallantoic membrane (CAM), as an extraembryonic tissue layer generated by the fusion of the chorion with the vascularized allantoic membrane, is…”
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Online dynamic pricing and consumer-perceived ethicality: Synthesis and future research
Published in Recherche et Applications en Marketing (English Edition) (01-09-2017)“…In the era of Big Data, online retailers’ pricing strategies are evolving towards an online dynamic pricing system, which consists in frequent modifications of…”
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Abstract 4018: An innovative in vivo model for CAR-T cell therapy development: Tolerability and efficacy evaluation of CD19-targeting CAR-T cells on human lymphoma using the chicken CAM assay
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract BACKGROUND Chimeric antigen receptor (CAR) T cell therapy is a revolutionary approach in cellular immunotherapy, where a patient’s T cells are…”
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Embryonated Chicken Tumor Xenografts Derived from Circulating Tumor Cells as a Relevant Model to Study Metastatic Dissemination: A Proof of Concept
Published in Cancers (23-08-2022)“…Patient-Derived Xenografts (PDXs) in the Chorioallantoic Membrane (CAM) are a representative model for studying human tumors. Circulating Tumor Cells (CTCs)…”
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Abstract 4866: Pharmacological mechanisms of osimertinib in advanced non-small lung cancer bearing the deletion exon 19 of EGFR In an original chicken chorioallantoic membrane (CAM) Model
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Introduction: NSCLC accounts for about 80-85% of all lung cancers. Approximately 10-50% of patients with NSCLC harbor EGFR activating mutations, such…”
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Enhancement of the Flotation Deinking Selectivity by Natural Polymeric Dispersants
Published in Industrial & engineering chemistry research (06-10-2010)“…The impact of natural polymeric dispersants, that is, carboxymethyl cellulose and guar gum, on the flotation selectivity was investigated on a flotation…”
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Abstract 365: Increased Plasma Cholesterol Esterification by Lecithin-Cholesterol Acyltransferase Prevents Dysfunction of Red Blood Cells and Platelets and Protects from Development of Diet-Induced Atherosclerosis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2013)“…Abstract only Introduction Free cholesterol plays a vital role in maintaining cell membrane fluidity and function. Elevated levels of cholesterol in red blood…”
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Abstract 450: Effects of Multiple Infusions of Recombinant LCAT on Plasma and Tissue Lipids and Expression of Genes Involved in Atherogenesis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2013)“…Abstract only BACKGROUND LCAT, an enzyme that converts small, discoidal HDL to spherical HDL particles by esterifying free cholesterol, plays a key role in…”
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In Vivo Evidence for a Role of Adipose Tissue SR-BI in the Nutritional and Hormonal Regulation of Adiposity and Cholesterol Homeostasis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-2007)“…OBJECTIVES—This study examines the role of insulin and angiotensin II in high-density lipoprotein (HDL) metabolism by focusing on the regulation and function…”
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