Search Results - "Rousselet, N"
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Expression of cathepsin L in human tumor cells is under the control of distinct regulatory mechanisms
Published in Oncogene (09-03-2006)“…Cathepsin L, a cysteine protease, is overexpressed in human tumor cells and plays a major role in melanoma progression. Our aim was herein to identify…”
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Intratumoral gene delivery of anti-cathepsin L single-chain variable fragment by lentiviral vector inhibits tumor progression induced by human melanoma cells
Published in Cancer gene therapy (01-09-2008)“…We previously demonstrated that the switch from non- to highly tumorigenic phenotype of human melanoma cells is directly related to procathepsin L secretion,…”
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WS17.03 An alternative mutation agnostic therapy for cystic fibrosis with oligonucleotide antisense
Published in Journal of cystic fibrosis (01-06-2023)Get full text
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628 A new oligonucleotide antisense therapy for all patients with cystic fibrosis
Published in Journal of cystic fibrosis (01-10-2022)Get full text
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Inhibition of tumorigenicity and metastasis of human melanoma cells by anti-cathepsin L single chain variable fragment
Published in Cancer research (Chicago, Ill.) (2004)“…We demonstrated previously that the switch from nonmetastatic to highly metastatic phenotype of human melanoma cells is directly related to secretion of…”
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Cloning and characterization of anti-cathepsin L single chain variable fragment whose expression inhibits procathepsin L secretion in human melanoma cells
Published in Biochemical journal (01-10-2002)“…We previously demonstrated that increase of procathepsin L secretion by human melanoma cells strongly increased their tumourigenicity and switched their…”
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The role of histidine 231 in thermolysin-like enzymes. A site-directed mutagenesis study
Published in The Journal of biological chemistry (14-07-1995)“…In the zinc metallopeptidases produced by the genus Bacillus, an active site histidine has been proposed to either stabilize the transition state in catalysis…”
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New Dual Inhibitors of Neutral Endopeptidase and Angiotensin-Converting Enzyme: Rational Design, Bioavailability, and Pharmacological Responses in Experimental Hypertension
Published in Journal of medicinal chemistry (01-04-1994)“…In the treatment of cardiovascular diseases, it could be of therapeutic interest to associate the hypotensive effects resulting from the inhibition of…”
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His super(381) of the rat CCK sub(B) receptor is essential for CCK sub(B) versus CCK sub(A) receptor antagonist selectivity
Published in European journal of pharmacology (01-01-1996)“…A great interest is devoted to antagonists of the cholecystokinin type B (CCK sub(B)) receptor such as L-365,260, which reduces panic attacks in humans and to…”
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His381 of the rat CCKB receptor is essential for CCKB versus CCKA receptor antagonist selectivity
Published in European journal of pharmacology (18-01-1996)“…A great interest is devoted to antagonists of the cholecystokinin type B (CCKB) receptor such as L-365,260, which reduces panic attacks in humans and to…”
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Some results of the treatment of leg ulcer with preserved homografts
Published in Bulletin de la Societe francaise de dermatologie et de syphiligraphie (01-07-1970)Get more information
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Status of the mental patient in 1976 in a psychiatric department of a general hospital
Published in Annales médico psychologiques (01-06-1976)Get more information
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Prevalence of depressive symptoms in a population of ambulatory schizophrenics
Published in Annales médico psychologiques (01-02-1983)Get more information
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Petges-Clejat poikilodermatomyositis of subacute development
Published in Bulletin de la Societe francaise de dermatologie et de syphiligraphie (1968)Get more information
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Subacute dermatomyositis
Published in Bulletin de la Societe francaise de dermatologie et de syphiligraphie (1968)Get more information
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Extensive scleroderma with rhizomelic onset
Published in Bulletin de la Societe francaise de dermatologie et de syphiligraphie (1968)Get more information
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