Search Results - "Roussel, Simon"

Behavioral Deficits After Distal Focal Cerebral Ischemia in Mice: Usefulness of Adhesive Removal Test by Freret, Thomas, Bouet, Valentine, Leconte, Claire, Roussel, Simon, Chazalviel, Laurent, Divoux, Didier, Schumann-Bard, Pascale, Boulouard, Michel

“…Distal occlusion of the middle cerebral artery (dMCAo), which closely mimics human stroke, is one of the most used animal models. However, although assessment…”
Get full text

Permanent or transient chronic ischemic stroke in the non-human primate: behavioral, neuroimaging, histological, and immunohistochemical investigations by Bihel, Ebeline, Pro-Sistiaga, Palma, Letourneur, Annelise, Toutain, Jerome, Saulnier, Romaric, Insausti, Ricardo, Bernaudin, Myriam, Roussel, Simon, Touzani, Omar

“…Using multimodal magnetic resonance imaging (MRI), behavioral, and immunohistochemical analyses, we examined pathological changes at the acute, sub-acute, and…”
Get full text

In vivo MRI tracking of exogenous monocytes/macrophages targeting brain tumors in a rat model of glioma by Valable, Samuel, Barbier, Emmanuel L., Bernaudin, Myriam, Roussel, Simon, Segebarth, Christoph, Petit, Edwige, Rémy, Chantal

“…This study has shown that murine monocytes/macrophages (Mo/Ma) can be labeled simply and efficiently with large, green-fluorescent, micrometer-sized particles…”
Get full text

Angiopoietin-2 is Vasoprotective in the Acute Phase of Cerebral Ischemia by Marteau, Léna, Valable, Samuel, Divoux, Didier, Roussel, Simon A, Touzani, Omar, MacKenzie, Eric T, Bernaudin, Myriam, Petit, Edwige

“…Most forms of cerebral ischemia are characterized by damage to the entire neurovascular unit, which leads to an increase in the permeability of the blood–brain…”
Get full text

A Potential Role for Erythropoietin in Focal Permanent Cerebral Ischemia in Mice by Bernaudin, Myriam, Marti, Hugo H., Roussel, Simon, Divoux, Didier, Nouvelot, André, MacKenzie, Eric T., Petit, Edwige

“…The present study describes, for the first time, a temporal and spatial cellular expression of erythropoietin (Epo) and Epo receptor (Epo-R) with the evolution…”
Get full text

Combined therapeutic strategy using erythropoietin and mesenchymal stem cells potentiates neurogenesis after transient focal cerebral ischemia in rats by Esneault, Elise, Pacary, Emilie, Eddi, Dauphou, Freret, Thomas, Tixier, Emmanuelle, Toutain, Jérôme, Touzani, Omar, Schumann-Bard, Pascale, Petit, Edwige, Roussel, Simon, Bernaudin, Myriam

“…Many studies showed beneficial effects of either erythropoietin (EPO) or mesenchymal stem cells (MSCs) treatment in cerebral ischemia. In addition to a…”
Get full text

Adrenomedullin protects neurons against oxygen glucose deprivation stress in an autocrine and paracrine manner by Tixier, Emmanuelle, Leconte, Claire, Touzani, Omar, Roussel, Simon, Petit, Edwige, Bernaudin, Myriam

“…The understanding of mechanisms involved in ischaemic brain tolerance may provide new therapeutical targets for stroke. In vivo genomic studies revealed an…”
Get full text

Chronic arterial hypertension impedes glioma growth: a multiparametric MRI study in the rat by Letourneur, Annelise, Roussel, Simon, Bernaudin, Myriam, Fillesoye, Fabien, Toutain, Jérôme, MacKenzie, Eric T, Petit, Edwige, Touzani, Omar, Valable, Samuel

“…Glioblastoma is the most aggressive brain tumor and is almost always fatal. These tumors are highly vascularized and angiogenesis is one of the pre-eminent…”
Get full text

Intraluminal thread model of focal stroke in the non-human primate by Freret, Thomas, Bouet, Valentine, Toutain, Jérôme, Saulnier, Romaric, Pro-Sistiaga, Palma, Bihel, Ebeline, MacKenzie, Eric T, Roussel, Simon, Schumann-Bard, Pascale, Touzani, Omar

“…The common marmoset (Callithrix jacchus), a New World monkey, has recently been used as a model of focal cerebral ischaemia. Here, we sought to develop a…”
Get full text

In vivo MRI tracking of exogenous monocytes/macrophages targeting brain tumors in a rat model of glioma by Valable, Samuel, Barbier, Emmanuel L., Bernaudin, Myriam, Roussel, Simon, Segebarth, Christoph, Petit, Edwige, Rémy, Chantal

“…This study has shown that murine monocytes/macrophages (Mo/Ma) can be labeled simply and efficiently with large, green-fluorescent, micrometer-sized particles…”
Get full text

Effects of urotensin-II on cerebral blood flow and ischemia in anesthetized rats by Chuquet, Julien, Lecrux, Clotilde, Chatenet, David, Leprince, Jérôme, Chazalviel, Laurent, Roussel, Simon, MacKenzie, Eric T., Vaudry, Hubert, Touzani, Omar

“…Urotensin-II (U-II) is a cyclic peptide identified recently in many mammalian species including man. U-II and its receptor are expressed in the central nervous…”
Get full text

The nature of penumbral depolarizations following focal cerebral ischemia in the rat by Nallet, Hélène, MacKenzie, Eric T, Roussel, Simon

“…It has been previously suggested that the transient ischemic depolarizations (IDs), thought involved in the gradual expansion of ischemic injury in the first…”
Get full text

Reduction of infarct volume by magnesium after middle cerebral artery occlusion in rats by Izumi, Y, Roussel, S, Pinard, E, Seylaz, J

“…The effects of magnesium, an endogenous inhibitor of calcium entry into neurons, upon ischemic brain damage were investigated using a well-characterized model…”
Get more information

Two-kidney one-clip is a pertinent approach to integrate arterial hypertension in animal models of stroke: Serial magnetic resonance imaging studies of brain lesions before and during cerebral ischemia by Ménard, Benjamin, Chazalviel, Laurent, Roussel, Simon, Bernaudin, Myriam, Touzani, Omar

“…Although chronic arterial hypertension (CAH) represents the major comorbid factor in stroke, it is rarely integrated in preclinical studies of stroke. The…”
Get full text

Delayed Hypoxic Postconditioning Protects Against Cerebral Ischemia in the Mouse by LECONTE, Claire, TIXIER, Emmanuelle, FRERET, Thomas, TOUTAIN, Jérôme, SAULNIER, Romaric, BOULOUARD, Michel, ROUSSEL, Simon, SCHUMANN-BARD, Pascale, BERNAUDIN, Myriam

“…Inspired from preconditioning studies, ischemic postconditioning, consisting of the application of intermittent interruptions of blood flow shortly after…”
Get full text

Impact of genetic and renovascular chronic arterial hypertension on the acute spatiotemporal evolution of the ischemic penumbra: a sequential study with MRI in the rat by Letourneur, Annelise, Roussel, Simon, Toutain, Jérôme, Bernaudin, Myriam, Touzani, Omar

“…Although chronic arterial hypertension (CAH) increases the risk of stroke and the severity of the resultant lesion, it is rarely integrated in preclinical…”
Get full text

Effects of mesenchymal stem cell therapy, in association with pharmacologically active microcarriers releasing VEGF, in an ischaemic stroke model in the rat by Quittet, Marie-Sophie, Touzani, Omar, Sindji, Laurence, Cayon, Jérôme, Fillesoye, Fabien, Toutain, Jérôme, Divoux, Didier, Marteau, Léna, Lecocq, Myriam, Roussel, Simon, Montero-Menei, Claudia N., Bernaudin, Myriam

“…[Display omitted] Few effective therapeutic interventions are available to limit brain damage and functional deficits after ischaemic stroke. Within this…”
Get full text

q-Space imaging of the brain by King, M D, Houseman, J, Roussel, S A, van Bruggen, N, Williams, S R, Gadian, D G

“…q-Space imaging (Callaghan, J. Magn. Reson. 88, 493 (1990)) has been used to obtain mouse brain water displacement profiles. These profiles take the form of a…”
Get more information

Diffusion Tensor MRI Reveals Chronic Alterations in White Matter Despite the Absence of a Visible Ischemic Lesion on Conventional MRI: A Nonhuman Primate Study by BIHEL, Ebeline, ROUSSEL, Simon, TOUTAIN, Jérôme, BERNAUDIN, Myriam, TOUZANI, Omar

“…The impact of stroke on white matter is poorly described in preclinical investigations mainly based on rodents with a low white (WM)/gray matter ratio. Using…”
Get full text

Brain ischemic injury in rodents: the protective effect of EPO by Letourneur, Annelise, Petit, Edwige, Roussel, Simon, Touzani, Omar, Bernaudin, Myriam

“…Animal models constitute an indispensable tool to investigate human pathology. Here we describe the procedure to induce permanent and transient cerebral…”
Get more information