Search Results - "Roussel, Ronan"

Protein- and diabetes-induced glomerular hyperfiltration: role of glucagon, vasopressin, and urea by Bankir, Lise, Roussel, Ronan, Bouby, Nadine

“…A single protein-rich meal (or an infusion of amino acids) is known to increase the glomerular filtration rate (GFR) for a few hours, a phenomenon known as…”
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More Similarities Than Differences Testing Insulin Glargine 300 Units/mL Versus Insulin Degludec 100 Units/mL in Insulin-Naive Type 2 Diabetes: The Randomized Head-to-Head BRIGHT Trial by Rosenstock, Julio, Cheng, Alice, Ritzel, Robert, Bosnyak, Zsolt, Devisme, Christine, Cali, Anna M G, Sieber, Jochen, Stella, Peter, Wang, Xiangling, Frías, Juan P, Roussel, Ronan, Bolli, Geremia B

“…To compare insulin glargine 300 units/mL (Gla-300) versus insulin degludec 100 units/mL (IDeg-100) in this first head-to-head randomized controlled trial…”
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SGLT2 inhibitors and lower limb complications: the diuretic-induced hypovolemia hypothesis by Potier, Louis, Mohammedi, Kamel, Velho, Gilberto, Roussel, Ronan

“…In a recent meta-analysis of randomized controlled trials of sodium glucose co-transporter 2 inhibitors (SGLT2i) in patients with diabetes, Lin and colleagues…”
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Prevention of cardiovascular disease through reduction of glycaemic exposure in type 2 diabetes: A perspective on glucose‐lowering interventions by Roussel, Ronan, Steg, Philippe Gabriel, Mohammedi, Kamel, Marre, Michel, Potier, Louis

“…Type 2 diabetes is a leading cause of cardiovascular disease (CVD). Observational studies have consistently shown an association between glycaemic level and…”
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Lower extremity arterial disease in patients with diabetes: a contemporary narrative review by Nativel, Mathilde, Potier, Louis, Alexandre, Laure, Baillet-Blanco, Laurence, Ducasse, Eric, Velho, Gilberto, Marre, Michel, Roussel, Ronan, Rigalleau, Vincent, Mohammedi, Kamel

“…Lower-extremity arterial disease (LEAD) is a major endemic disease with an alarming increased prevalence worldwide. It is a common and severe condition with…”
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Stay-at-Home Orders During the COVID-19 Pandemic, an Opportunity to Improve Glucose Control Through Behavioral Changes in Type 1 Diabetes by Potier, Louis, Hansel, Boris, Larger, Etienne, Gautier, Jean-François, Carreira, Daphné, Assemien, Rachel, Lantieri, Olivier, Riveline, Jean-Pierre, Roussel, Ronan

“…To investigate the impact of coronavirus disease 2019 lockdown on glycemic control and associated factors in people living with type 1 diabetes. An…”
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Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans by Wigger, Leonore, Cruciani-Guglielmacci, Céline, Nicolas, Anthony, Denom, Jessica, Fernandez, Neïké, Fumeron, Frédéric, Marques-Vidal, Pedro, Ktorza, Alain, Kramer, Werner, Schulte, Anke, Le Stunff, Hervé, Liechti, Robin, Xenarios, Ioannis, Vollenweider, Peter, Waeber, Gérard, Uphues, Ingo, Roussel, Ronan, Magnan, Christophe, Ibberson, Mark, Thorens, Bernard

“…Plasma metabolite concentrations reflect the activity of tissue metabolic pathways and their quantitative determination may be informative about pathogenic…”
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Low Water Intake and Risk for New-Onset Hyperglycemia by Roussel, Ronan, Fezeu, Léopold, Bouby, Nadine, Balkau, Beverley, Lantieri, Olivier, Alhenc-Gelas, François, Marre, Michel, Bankir, Lise

“…OBJECTIVE: Water intake alters vasopressin secretion. Recent findings reveal an independent association between plasma copeptin, a surrogate for vasopressin,…”
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Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes by Bonnefond, Amélie, Clément, Nathalie, Fawcett, Katherine, Yengo, Loïc, Vaillant, Emmanuel, Guillaume, Jean-Luc, Dechaume, Aurélie, Payne, Felicity, Roussel, Ronan, Czernichow, Sébastien, Hercberg, Serge, Hadjadj, Samy, Balkau, Beverley, Marre, Michel, Lantieri, Olivier, Langenberg, Claudia, Bouatia-Naji, Nabila, Charpentier, Guillaume, Vaxillaire, Martine, Rocheleau, Ghislain, Wareham, Nicholas J, Sladek, Robert, McCarthy, Mark I, Dina, Christian, Barroso, Inês, Jockers, Ralf, Froguel, Philippe

“…Philippe Froguel, Ralf Jockers and colleagues report the functional characterization of 40 rare protein-coding variants of the MTNR1B gene (encoding melatonin…”
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Plasma Copeptin, AVP Gene Variants, and Incidence of Type 2 Diabetes in a Cohort From the Community by Roussel, Ronan, El Boustany, Ray, Bouby, Nadine, Potier, Louis, Fumeron, Frédéric, Mohammedi, Kamel, Balkau, Beverley, Tichet, Jean, Bankir, Lise, Marre, Michel, Velho, Gilberto

“…Context: Experimental data support a role for vasopressin in metabolic disorders. Objective: We investigated associations of plasma copeptin, a surrogate of…”
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The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward by Ndiaye, Fatou K., Huyvaert, Marlène, Ortalli, Ana, Canouil, Mickaël, Lecoeur, Cécile, Verbanck, Marie, Lobbens, Stéphane, Khamis, Amna, Marselli, Lorella, Marchetti, Piero, Kerr-Conte, Julie, Pattou, François, Marre, Michel, Roussel, Ronan, Balkau, Beverley, Froguel, Philippe, Bonnefond, Amélie

“…Background Genome-wide association studies (GWAS) have identified more than 250 loci associated with body mass index (BMI) and obesity. However, post-GWAS…”
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Plasma concentrations of lipoproteins and risk of lower-limb peripheral artery disease in people with type 2 diabetes: the SURDIAGENE study by Bertrand, Capucine, Saulnier, Pierre-Jean, Potier, Louis, Croyal, Mikaël, Blanchard, Valentin, Gand, Elise, Ragot, Stéphanie, Schneider, Fabrice, Bocock, Olivia, Baillet-Blanco, Laurence, Velho, Gilberto, Marre, Michel, Roussel, Ronan, Rigalleau, Vincent, Hadjadj, Samy, Mohammedi, Kamel

“…Aims/hypothesis The lipid profile has not been fully investigated in individuals with peripheral artery disease (PAD). We aimed to evaluate the relationship…”
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Monocytopenia, monocyte morphological anomalies and hyperinflammation characterise severe COVID‐19 in type 2 diabetes by Alzaid, Fawaz, Julla, Jean‐Baptiste, Diedisheim, Marc, Potier, Charline, Potier, Louis, Velho, Gilberto, Gaborit, Bénédicte, Manivet, Philippe, Germain, Stéphane, Vidal‐Trecan, Tiphaine, Roussel, Ronan, Riveline, Jean‐Pierre, Dalmas, Elise, Venteclef, Nicolas, Gautier, Jean‐François

“…Early in the COVID‐19 pandemic, type 2 diabetes (T2D) was marked as a risk factor for severe disease and mortality. Inflammation is central to the aetiology of…”
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Vasopressin and hydration play a major role in the development of glucose intolerance and hepatic steatosis in obese rats by Taveau, Christopher, Chollet, Catherine, Waeckel, Ludovic, Desposito, Dorinne, Bichet, Daniel G., Arthus, Marie-Françoise, Magnan, Christophe, Philippe, Erwann, Paradis, Valerie, Foufelle, Fabienne, Hainault, Isabelle, Enhorning, Sofia, Velho, Gilberto, Roussel, Ronan, Bankir, Lise, Melander, Olle, Bouby, Nadine

“…Aims/hypothesis High plasma copeptin, a marker of vasopressin (VP) secretion, has been shown to be associated with the metabolic syndrome and development of…”
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Regulation of inflammation in diabetes: From genetics to epigenomics evidence by Diedisheim, Marc, Carcarino, Elena, Vandiedonck, Claire, Roussel, Ronan, Gautier, Jean-François, Venteclef, Nicolas

“…Diabetes is one of the greatest public health challenges worldwide, and we still lack complementary approaches to significantly enhance the efficacy of…”
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Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function by Meulebrouck, Sarah, Merrheim, Judith, Queniat, Gurvan, Bourouh, Cyril, Derhourhi, Mehdi, Boissel, Mathilde, Yi, Xiaoyan, Badreddine, Alaa, Boutry, Raphaël, Leloire, Audrey, Toussaint, Bénédicte, Amanzougarene, Souhila, Vaillant, Emmanuel, Durand, Emmanuelle, Loiselle, Hélène, Huyvaert, Marlène, Dechaume, Aurélie, Scherrer, Victoria, Marchetti, Piero, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Marre, Michel, Roussel, Ronan, Scharfmann, Raphaël, Cnop, Miriam, Canouil, Mickaël, Baron, Morgane, Froguel, Philippe, Bonnefond, Amélie

“…Functional genetics has identified drug targets for metabolic disorders. Opioid use impacts metabolic homeostasis, although mechanisms remain elusive. Here, we…”
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Automated Ankle-Brachial Pressure Index Measurement by Clinical Staff for Peripheral Arterial Disease Diagnosis in Nondiabetic and Diabetic Patients by Clairotte, Cécile, Retout, Sylvie, Potier, Louis, Roussel, Ronan, Escoubet, Brigitte

“…OBJECTIVE: Peripheral arterial disease (PAD) is a prognostic marker in cardiovascular disease. The use of Doppler-measured ankle-brachial pressure index…”
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Plasma copeptin, kidney disease, and risk for cardiovascular morbidity and mortality in two cohorts of type 2 diabetes by Velho, Gilberto, Ragot, Stéphanie, El Boustany, Ray, Saulnier, Pierre-Jean, Fraty, Mathilde, Mohammedi, Kamel, Fumeron, Frédéric, Potier, Louis, Marre, Michel, Hadjadj, Samy, Roussel, Ronan

“…Cardiovascular disease and kidney damage are tightly associated in people with type 2 diabetes. Experimental evidence supports a causal role for vasopressin…”
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Leukocyte telomere length, allelic variations in related genes and risk of coronary heart disease in people with long-standing type 1 diabetes by Sanchez, Manuel, Kannengiesser, Caroline, Hoang, Sophie, Potier, Louis, Fumeron, Frédéric, Venteclef, Nicolas, Scheen, André, Gautier, Jean-François, Hadjadj, Samy, Marre, Michel, Roussel, Ronan, Mohammedi, Kamel, Velho, Gilberto

“…Abstract Background Type 1 diabetes is associated with accelerated vascular aging and advanced atherosclerosis resulting in increased rates of cardiovascular…”
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Body-weight variability and risk of cardiovascular outcomes in patients with type 1 diabetes: a retrospective observational analysis of data from the DCCT/EDIC population by Petria, Iulia, Albuquerque, Samuel, Varoquaux, Gaël, Vie, Jill-Jênn, Venteclef, Nicolas, Mohammedi, Kamel, Roussel, Ronan, Camoin, Marion, Perseghin, Gianluca, Velho, Gilberto, Potier, Louis

“…Cardiovascular risk and body-weight management are both emerging challenges of type 1 diabetes care. We evaluated the association between intraindividual…”
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