Search Results - "Roussel, M.F."

p53-Dependent and -Independent Functions of the Arf Tumor Suppressor by SHERR, C.J., BERTWISTLE, D., DEN BESTEN, W., KUO, M.-L., SUGIMOTO, M., TAGO, K., WILLIAMS, R.T., ZINDY, F., ROUSSEL, M.F.

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E2-RING Expansion of the NEDD8 Cascade Confers Specificity to Cullin Modification by Huang, Danny T., Ayrault, Olivier, Hunt, Harold W., Taherbhoy, Asad M., Duda, David M., Scott, Daniel C., Borg, Laura A., Neale, Geoffrey, Murray, Peter J., Roussel, Martine F., Schulman, Brenda A.

“…Ubiquitin and ubiquitin-like proteins (UBLs) are directed to targets by cascades of E1, E2, and E3 enzymes. The largest ubiquitin E3 subclass consists of…”
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Preclinical Modeling of Clinically Relevant Radiation Therapy for Treatment of High-Risk Medulloblastoma by Smith, S.M.C., Tinkle, C.L., Bianski, B.M., Orr, B.A., Robinson, G.W., Morel, V., Gilbertson, R.J., Gajjar, A., Merchant, T.E., Roussel, M.F.

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Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance by Lindsey, J C, Kawauchi, D, Schwalbe, E C, Solecki, D J, Selby, M P, McKinnon, P J, Olson, J M, Hayden, J T, Grundy, R G, Ellison, D W, Williamson, D, Bailey, S, Roussel, M F, Clifford, S C

“…The identification of key tumorigenic events in Sonic Hedgehog (SHH) subgroup medulloblastomas (MB SHH ) will be essential for the development of…”
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Macrophage colony-stimulating factor, CSF-1, and its proto-oncogene-encoded receptor by Sherr, C J, Rettenmier, C W, Roussel, M F

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Activation of Src family kinases by colony stimulating factor‐1, and their association with its receptor by Courtneidge, S.A., Dhand, R., Pilat, D., Twamley, G.M., Waterfield, M.D., Roussel, M.F.

“…The receptor for the macrophage colony stimulating factor‐1 (CSF‐1R) is a transmembrane glycoprotein with intrinsic tyrosine kinase activity. CSF‐1 stimulation…”
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A Point Mutation at Tyrosine-809 in the Human Colony-Stimulating Factor 1 Receptor Impairs Mitogenesis Without Abrogating Tyrosine Kinase Activity, Association With Phosphatidylinositol 3-Kinase, or Induction of c-Fos and JunB Genes by Roussel, Martine F., Shurtleff, Sheila A., Downing, James R., Sherr, Charles J.

“…Substitution of phenylalanine for tyrosine-809 in the human colony-stimulating factor 1 receptor (CSF-1R) inhibited its ability to transduce ligand-dependent…”
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D-type cyclins and their cyclin-dependent kinases: G1 phase integrators of the mitogenic response by Sherr, C J, Kato, J, Quelle, D E, Matsuoka, M, Roussel, M F

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Novel mammalian cyclins (CYL genes) expressed during G1 by Matsushime, H, Roussel, M F, Sherr, C J

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Random mutagenesis of CSF‐1 receptor (FMS) reveals multiple sites for activating mutations within the extracellular domain by Daalen Wetters, T., Hawkins, S.A., Roussel, M.F., Sherr, C.J.

“…Retroviral vectors containing human FMS protooncogene cDNA were reconfigured to allow single‐step excision and reinsertion of restriction fragments encoding…”
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Colony-Stimulating Factor 1-Mediated Regulation of a Chimeric c-fms/v-fms Receptor Containing the v-fms-Encoded Tyrosine Kinase Domain by Roussel, Martine F., Downing, James R., Ashmun, Richard A., Rettenmier, Carl W., Sherr, Charles J.

“…A chimeric gene specifying the 308 N-terminal amino acids of the extracellular ligand binding domain of the human c-fms protooncogene joined to the remainder…”
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