Search Results - "Rourke, Colm O"

Loss of Actin-Binding LIM protein (ABLIM) plays a potential role in migratory cholangiocyte transformation by Duwe, Lea, Munoz-Garrido, Patricia, Lafuente-Barquero, Juan, Rourke, Colm O, Marquardt, Jens, Andersen, Jesper

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OS-024-YI - Scavenger receptor MARCO is associated with an immunosuppressive microenvironment and tumor progression in intrahepatic cholangiocarcinoma by Lizaso, Aloña Agirre, Izagirre, Maider Huici, Rourke, Colm O, Zhuravleva, Ekaterina, Korosec, Ana, Azkargorta, Mikel, Elortza, Felix, Ilyas, Sumera I., Gores, Gregory, Andersen, Jesper, Schabbauer, Gernot, Bujanda, Luis, Rodrigues, Pedro Miguel, Sharif, Omar, Banales, Jesus Maria, Perugorria, María Jesús

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SAT-226 - KLF5 upregulation is a common event in cholangiocarcinoma, acting as an oncogene and constituting a bad prognostic factor by Rodrigues, Pedro Miguel, Erice, Oihane, Landa-Magdalena, Ana, Paiva, Nuno, Fernandez-Barrena, Maite G, Olaizola, Paula, Lapitz, Ainhoa, Rourke, Colm O, Andersen, Jesper, Calvisi, Diego, Azkargorta, Mikel, Elortza, Felix, Goicoechea, Ibai, Lawrie, Charles, Bujanda, Luis, Perugorria, María Jesús, Banales, Jesus Maria

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Scavenger receptor MARCO is associated with an immunosuppressive microenvironment and tumor progression in intrahepatic cholangiocarcinoma by Lizaso, Aloña Agirre, Izagirre, Maider Huici, Rourke, Colm O, Zhuravleva, Ekaterina, Korosec, Ana, Azkargorta, Mikel, Elortza, Felix, Ilyas, Sumera I., Gores, Gregory, Andersen, Jesper, Schabbauer, Gernot, Bujanda, Luis, Rodrigues, Pedro Miguel, Sharif, Omar, Banales, Jesus Maria, Perugorria, María Jesús

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KLF5 upregulation is a common event in cholangiocarcinoma, acting as an oncogene and constituting a bad prognostic factor by Rodrigues, Pedro Miguel, Erice, Oihane, Landa-Magdalena, Ana, Paiva, Nuno, Fernandez-Barrena, Maite G, Olaizola, Paula, Lapitz, Ainhoa, Rourke, Colm O, Andersen, Jesper, Calvisi, Diego, Azkargorta, Mikel, Elortza, Felix, Goicoechea, Ibai, Lawrie, Charles, Bujanda, Luis, Perugorria, María Jesús, Banales, Jesus Maria

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PS-044-Identification of a pan-gamma-secretase inhibitor response signature for notch-driven cholangiocarcinoma by Rourke, Colm O, Matter, Matthias, Nepal, Chirag, Ton, Phuongnga, Factor, Valentina, Andersen, Jesper

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FRI-472-YI Mitochondrial metabolism is disrupted by ciprofloxacin preventing cholangiocarcinoma cell proliferation by de Gauna, Mikel Ruiz, Alfaro-Jiménez, Kendall, Nieva-Zuluaga, Ane, Apodaka-Biguri, Maider, Markaide, Enara, Izquierdo-Sánchez, Laura, Rae, Colin, González-Romero, Francisco, Gomez-Jauregui, Paul, Sainz-Ramírez, Natalia, Santos, Beatriz Gómez, Buque, Xabier, Aurrekoetxea, Igor, Delgado, Igotz, Fernández-Puertas, Idoia, Iglesias, Ainhoa, Rourke, Colm O., Rodrigues, Pedro Miguel, Andersen, Jesper, Calvisi, Diego, Morton, Jennifer, Braconi, Chiara, Zubiaga, Ana, Banales, Jesus Maria, Aspichueta, Patricia

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THU-251 - CD73high biliary tract cancer (BTC): a molecularly-defined subtype with distinct clinical implications by Salati, Massimiliano, Barbato, Anna, Piscopo, Fabiola, Evangelista, Lorenzo, Gambardella, Gennaro, Sarnataro, Sergio, Petrillo, Angelica, Daniele, Bruno, Pisapia, Pasquale, Salatiello, Maria, Malapelle, Umberto, Troncone, Giancarlo, Spallanzani, Andrea, Gelsomino, Fabio, Ricco’, Beatrice, Iuliano, Antonella, Reggiani-Bonetti, Luca, Rourke, Colm O, Andersen, Jesper, Dominici, Massimo, Franco, Brunella, Carotenuto, Pietro

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Therapeutic potential of targeting protein hyper-SUMOylation in cholangiocarcinoma by Olaizola, Paula, Olaizola, Irene, de Ara, Marta Fernandez, Fernandez-Barrena, Maite G, Alvarez, Laura, Azkargorta, Mikel, Rourke, Colm O, Lee-Law, Pui-Yuen, Nova-Camacho, Luiz Miguel, Marin, Jose, Martínez-Chantar, María Luz, Avila, Matías A, Aspichueta, Patricia, Elortza, Felix, Andersen, Jesper, Bujanda, Luis, Rodrigues, Pedro Miguel, Perugorria, María Jesús, Banales, Jesus Maria

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SAT-223 - Therapeutic potential of targeting protein hyper-SUMOylation in cholangiocarcinoma by Olaizola, Paula, Olaizola, Irene, de Ara, Marta Fernandez, Fernandez-Barrena, Maite G, Alvarez, Laura, Azkargorta, Mikel, Rourke, Colm O, Lee-Law, Pui-Yuen, Nova-Camacho, Luiz Miguel, Marin, Jose, Martínez-Chantar, María Luz, Avila, Matías A, Aspichueta, Patricia, Elortza, Felix, Andersen, Jesper, Bujanda, Luis, Rodrigues, Pedro Miguel, Perugorria, María Jesús, Banales, Jesus Maria

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SAT-230 - Positive effects of PARP-1 inhibition in KRAS-mutated intrahepatic cholangiocarcinoma is mediated by CHK1 kinase by Castven, Darko, Keggenhoff, Friederike, Stojkovic, Stojan, Becker, Diana, Castven, Jovana, Zimpel, Carolin, Straub, Beate, Langer, Harald, Hähnel, Patrizia, Kindler, Thomas, Fahrer, Jörg, Rourke, Colm O, Ma, Lichun, Wang, Xin W., Gaiser, Timo, Matter, Matthias, Sina, Christian, Derer, Stefanie, Roessler, Stephanie, Kaina, Bernd, Andersen, Jesper, Galle, Peter, Marquardt, Jens

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CD73high biliary tract cancer (BTC): a molecularly-defined subtype with distinct clinical implications by Salati, Massimiliano, Barbato, Anna, Piscopo, Fabiola, Evangelista, Lorenzo, Gambardella, Gennaro, Sarnataro, Sergio, Petrillo, Angelica, Daniele, Bruno, Pisapia, Pasquale, Salatiello, Maria, Malapelle, Umberto, Troncone, Giancarlo, Spallanzani, Andrea, Gelsomino, Fabio, Ricco’, Beatrice, Iuliano, Antonella, Reggiani-Bonetti, Luca, Rourke, Colm O, Andersen, Jesper, Dominici, Massimo, Franco, Brunella, Carotenuto, Pietro

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Positive effects of PARP-1 inhibition in KRAS-mutated intrahepatic cholangiocarcinoma is mediated by CHK1 kinase by Castven, Darko, Keggenhoff, Friederike, Stojkovic, Stojan, Becker, Diana, Castven, Jovana, Zimpel, Carolin, Straub, Beate, Langer, Harald, Hähnel, Patrizia, Kindler, Thomas, Fahrer, Jörg, Rourke, Colm O, Ma, Lichun, Wang, Xin W., Gaiser, Timo, Matter, Matthias, Sina, Christian, Derer, Stefanie, Roessler, Stephanie, Kaina, Bernd, Andersen, Jesper, Galle, Peter, Marquardt, Jens

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Circulating vesicles hold etiology-related protein biomarkers of cholangiocarcinoma risk, early diagnosis and prognosis mirroring tumour cells by Lapitz, Ainhoa, Azkargorta, Mikel, Zhuravleva, Ekaterina, Grimsrud, Marit M., Rourke, Colm O., Arbelaiz, Ander, La Casta, Adelaida, Vesterhus, Mette, Milkiewicz, Piotr, Milkiewicz, Malgorzata, Jimenez-Aguero, Raul, Pastor, Tania, Macias, Rocio IR, Riaño, Ioana, Izquierdo-Sánchez, Laura, Krawczyk, Marcin, Ibarra, Cesar, Bustamante, Javier, Elortza, Felix, Falcon-Perez, Juan, Perugorria, María Jesús, Andersen, Jesper, Bujanda, Luis, Karlsen, Tom Hemming, Folseraas, Trine, Rodrigues, Pedro Miguel, Banales, Jesus Maria

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Liquid biopsy protein biomarkers of cholangiocarcinoma risk, early diagnosis and survival mirroring tumor cells by Lapitz, Ainhoa, Azkargorta, Mikel, Milkiewicz, Piotr, Olaizola, Paula, Zhuravleva, Ekaterina, Grimsrud, Marit M., Schramm, Christoph, Arbelaiz, Ander, Rourke, Colm O, La Casta, Adelaida, Milkiewicz, Malgorzata, Pastor, Tania, Vesterhus, Mette, Jimenez-Aguero, Raul, Dill, Michael, Lamarca, Angela, Valle, Juan, Macias, Rocio IR, Izquierdo-Sánchez, Laura, Castaño, Ylenia Pérez, Caballero, Francisco J., Riaño, Ioana, Krawczyk, Marcin, Ibarra, Cesar, Bustamante, Javier, Nova-Camacho, Luiz Miguel, Falcon-Perez, Juan, Elortza, Felix, Perugorria, María Jesús, Andersen, Jesper, Bujanda, Luis, Karlsen, Tom Hemming, Folseraas, Trine, Rodrigues, Pedro Miguel, Banales, Jesus Maria

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SAT-238 - Liquid biopsy protein biomarkers of cholangiocarcinoma risk, early diagnosis and survival mirroring tumor cells by Lapitz, Ainhoa, Azkargorta, Mikel, Milkiewicz, Piotr, Olaizola, Paula, Zhuravleva, Ekaterina, Grimsrud, Marit M., Schramm, Christoph, Arbelaiz, Ander, Rourke, Colm O, La Casta, Adelaida, Milkiewicz, Malgorzata, Pastor, Tania, Vesterhus, Mette, Jimenez-Aguero, Raul, Dill, Michael, Lamarca, Angela, Valle, Juan, Macias, Rocio IR, Izquierdo-Sánchez, Laura, Castaño, Ylenia Pérez, Caballero, Francisco J., Riaño, Ioana, Krawczyk, Marcin, Ibarra, Cesar, Bustamante, Javier, Nova-Camacho, Luiz Miguel, Falcon-Perez, Juan, Elortza, Felix, Perugorria, María Jesús, Andersen, Jesper, Bujanda, Luis, Karlsen, Tom Hemming, Folseraas, Trine, Rodrigues, Pedro Miguel, Banales, Jesus Maria

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Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models by Olaizola, Paula, Lee-Law, Pui Yuen, Fernandez-Barrena, Maite G, Alvarez, Laura, Cadamuro, Massimiliano, Azkargorta, Mikel, O'Rourke, Colm J, Caballero-Camino, Francisco J, Olaizola, Irene, Macias, Rocio I R, Marin, Jose J G, Serrano-Maciá, Marina, Martinez-Chantar, Maria L, Avila, Matias A, Aspichueta, Patricia, Calvisi, Diego F, Evert, Matthias, Fabris, Luca, Castro, Rui E, Elortza, Felix, Andersen, Jesper B, Bujanda, Luis, Rodrigues, Pedro M, Perugorria, Maria J, Banales, Jesus M

“…Cholangiocarcinoma (CCA) comprises a heterogeneous group of malignant tumors associated with dismal prognosis. Alterations in post-translational modifications…”
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Novel protein biomarkers in serum extracellular vesicles for the diagnosis of cholangiocarcinoma (CCA) in patients with primary sclerosing cholangitis (PSC) by Lapitz, Ainhoa, Azkargorta, Mikel, Rourke, Colm O, Arbelaiz, Ander, La Casta, Adelaida, Vesterhus, Mette, Milkiewicz, Piotr, Jimenez-Aguero, Raul, Riaño, Ioana, Landa, Ana, Ibarra, Cesar, Bustamante, Javier, Perugorria, María Jesús, Bujanda, Luis, Rodrigues, Pedro Miguel, Andersen, Jesper, Elortza, Felix, Folseraas, Trine, Karlsen, Tom Hemming, Banales, Jesus M.

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TREM2 protects the liver against hepatocellular carcinoma through multifactorial protective mechanisms by Labiano, Ibone, Esparza-Baquer, Aitor, Sharif, Omar, Agirre-Lizaso, Alona, Oakley, Fiona, Rodrigues, Pedro Miguel, Hijona, Elizabeth, Jimenez-Agüero, Raul, Landa, Ana, La Casta, Adelaida, William Zaki, Marco Youssef, Rourke, Colm O., Munoz-Garrido, Patricia, Azkargorta, Mikel, Elortza, Felix, Schabbauer, Gernot, Andersen, Jesper, Knapp, Sylvia, Mann, Derek A., Bujanda, Luis, Banales, Jesus M., Perugorria, María Jesús

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SAT054 - mIR-21 is increased in patients with NASH-associated HCC and contributes to hepatocarcinogenesis in mice with NAFLD by Rodrigues, Pedro Miguel, Afonso, Marta B., Simão, André, Islam, Tawhidul, Gaspar, Maria Manuela, Rourke, Colm O, Andersen, Jesper, Santos-Laso, Alvaro, Jimenez-Aguero, Raul, Eizaguirre, Emma, Bujanda, Luis, Pareja, María Jesús, Prip-Buus, Carina, Banales, Jesus M., Rodrigues, Cecília M.P., Castro, Rui E.

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