Search Results - "Rouleau"

Decreasing the Risk of Heart Failure in a Changing Post–Myocardial Infarction Environment by Rouleau, Jean

“…A number of therapies that have been shown to be effective in patients with chronic heart failure, including beta-blockers, mineralocorticoid receptor…”
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Micro-Practices of Strategic Sensemaking and Sensegiving: How Middle Managers Interpret and Sell Change Every Day by Rouleau, Linda

“…This paper looks at the workings of ongoing primary sensemaking and sensegiving micro‐practices by which middle managers interpret and sell strategic change at…”
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Impacts of the COVID-19 lockdown on energy consumption in a Canadian social housing building by Rouleau, Jean, Gosselin, Louis

“…•Energy use in a residential building was compared before and during COVID lockdown.•At the beginning of the lockdown, electricity use in the middle of the day…”
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‘Does Our Work Matter?’ The Role of Organizational Researchers in Extreme (War)Times by Rouleau, Linda

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Emerging roles for UDP-glucuronosyltransferases in drug resistance and cancer progression by Allain, Eric P., Rouleau, Michèle, Lévesque, Eric, Guillemette, Chantal

“…The best-known role of UDP-glucuronosyltransferase enzymes (UGTs) in cancer is the metabolic inactivation of drug therapies. By conjugating glucuronic acid to…”
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Deletion of C9ORF72 results in motor neuron degeneration and stress sensitivity in C. elegans by Therrien, Martine, Rouleau, Guy A, Dion, Patrick A, Parker, J Alex

“…An expansion of the hexanucleotide GGGGCC repeat in the first intron of C9ORF72 gene was recently linked to amyotrophic lateral sclerosis. It is not known if…”
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Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure by McMurray, John J.V, Packer, Milton, Desai, Akshay S, Gong, Jianjian, Lefkowitz, Martin P, Rizkala, Adel R, Rouleau, Jean L, Shi, Victor C, Solomon, Scott D, Swedberg, Karl, Zile, Michael R

“…The angiotensin receptor–neprilysin inhibitor LCZ696 was compared with the ACE inhibitor enalapril in patients with advanced heart failure. LCZ696 was superior…”
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The impact of phenotypic and genetic heterogeneity on results of genome wide association studies of complex diseases by Manchia, Mirko, Cullis, Jeffrey, Turecki, Gustavo, Rouleau, Guy A, Uher, Rudolf, Alda, Martin

“…Phenotypic misclassification (between cases) has been shown to reduce the power to detect association in genetic studies. However, it is conceivable that…”
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My Journey to Open Science by Rouleau, Guy

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Prognostic Implications of Changes in N-Terminal Pro-B-Type Natriuretic Peptide in Patients With Heart Failure by Zile, Michael R., MD, Claggett, Brian L., PhD, Prescott, Margaret F., PhD, McMurray, John J.V., MD, Packer, Milton, MD, Rouleau, Jean L., MD, Swedberg, Karl, MD, Desai, Akshay S., MD, Gong, Jianjian, PhD, Shi, Victor C., MD, Solomon, Scott D., MD

“…Abstract Background Natriuretic peptides (NP) have prognostic value in heart failure (HF), although the clinical importance of changes in NP from baseline is…”
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Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease by Gan-Or, Ziv, Dion, Patrick A, Rouleau, Guy A

“…Parkinson disease (PD), once considered as a prototype of a sporadic disease, is now known to be considerably affected by various genetic factors, which…”
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Middle Managers, Strategic Sensemaking, and Discursive Competence by Rouleau, Linda, Balogun, Julia

“…This paper seeks to better understand the way middle managers contribute strategically to the development of an organization by examining how they enact the…”
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TARDBP and FUS Mutations Associated with Amyotrophic Lateral Sclerosis: Summary and Update by Lattante, Serena, Rouleau, Guy A., Kabashi, Edor

“…ABSTRACT Mutations in the TAR DNA Binding Protein gene (TARDBP), encoding the protein TDP‐43, were identified in amyotrophic lateral sclerosis (ALS) patients…”
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Probabilistic window opening model considering occupant behavior diversity: A data-driven case study of Canadian residential buildings by Rouleau, Jean, Gosselin, Louis

“…It was found from monitored data from eight dwellings in a case study building in Quebec City (Canada) that there are clear differences in the window opening…”
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Effect of the angiotensin-receptor-neprilysin inhibitor LCZ696 compared with enalapril on mode of death in heart failure patients by Desai, Akshay S, McMurray, John J V, Packer, Milton, Swedberg, Karl, Rouleau, Jean L, Chen, Fabian, Gong, Jianjian, Rizkala, Adel R, Brahimi, Abdel, Claggett, Brian, Finn, Peter V, Hartley, Loren Howard, Liu, Jiankang, Lefkowitz, Martin, Shi, Victor, Zile, Michael R, Solomon, Scott D

“…The angiotensin-receptor-neprilysin inhibitor (ARNI) LCZ696 reduced cardiovascular deaths and all-cause mortality compared with enalapril in patients with…”
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De novo mutations in moderate or severe intellectual disability by Hamdan, Fadi F, Srour, Myriam, Capo-Chichi, Jose-Mario, Daoud, Hussein, Nassif, Christina, Patry, Lysanne, Massicotte, Christine, Ambalavanan, Amirthagowri, Spiegelman, Dan, Diallo, Ousmane, Henrion, Edouard, Dionne-Laporte, Alexandre, Fougerat, Anne, Pshezhetsky, Alexey V, Venkateswaran, Sunita, Rouleau, Guy A, Michaud, Jacques L

“…Genetics is believed to have an important role in intellectual disability (ID). Recent studies have emphasized the involvement of de novo mutations (DNMs) in…”
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Pharmacogenomics of Human Uridine Diphospho-Glucuronosyltransferases and Clinical Implications by Guillemette, C, Lévesque, É, Rouleau, M

“…Glucuronidation by uridine diphospho‐glucuronosyltransferase enzymes (UGTs) is a major phase II biotransformation pathway and, complementary to phase I…”
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Right ventricular dysfunction and risk of heart failure and mortality after myocardial infarction by Zornoff, Leonardo A.M., Skali, Hicham, Pfeffer, Marc A., St. John Sutton, Martin, Rouleau, Jean L., Lamas, Gervasio A., Plappert, Ted, Rouleau, Jacques R., Moyé, Lemuel A., Lewis, Sandra J., Braunwald, Eugene, Solomon, Scott D.

“…The aim of this study was to determine the prognostic value of right ventricular (RV) function in patients after a myocardial infarction (MI). Right…”
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Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression by Sequeira, Adolfo, Mamdani, Firoza, Ernst, Carl, Vawter, Marquis P, Bunney, William E, Lebel, Veronique, Rehal, Sonia, Klempan, Tim, Gratton, Alain, Benkelfat, Chawki, Rouleau, Guy A, Mechawar, Naguib, Turecki, Gustavo

“…Most studies investigating the neurobiology of depression and suicide have focused on the serotonergic system. While it seems clear that serotonergic…”
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Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients’ responsiveness to lithium by Stern, S, Santos, R, Marchetto, M C, Mendes, A P D, Rouleau, G A, Biesmans, S, Wang, Q-W, Yao, J, Charnay, P, Bang, A G, Alda, M, Gage, F H

“…Bipolar disorder (BD) is a progressive psychiatric disorder with more than 3% prevalence worldwide. Affected individuals experience recurrent episodes of…”
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